TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
Balka, Katherine R., Louis, Cynthia, Saunders, Tahnee L., Smith, Amber M., Calleja, Dale J., D’Silva, Damian B., Moghaddas, Fiona, Tailler, Maximilien, Lawlor, Kate E., Zhan, Yifan, Burns, Christopher J., Wicks, Ian P., Miner, Jonathan J., Kile, Benjamin T., Masters, Seth L., De Nardo, Dominic
Published in Cell reports (Cambridge) (07.04.2020)
Published in Cell reports (Cambridge) (07.04.2020)
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A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in Infancy
Saldanha, Rohit G, Balka, Katherine R, Davidson, Sophia, Wainstein, Brynn K, Wong, Melanie, Macintosh, Rebecca, Loo, Christine K C, Weber, Martin A, Kamath, Vasanth, Moghaddas, Fiona, De Nardo, Dominic, Gray, Paul Edgar, Masters, Seth Lucian
Published in Frontiers in immunology (06.07.2018)
Published in Frontiers in immunology (06.07.2018)
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Journal Article
Connexin-Dependent Transfer of cGAMP to Phagocytes Modulates Antiviral Responses
Pépin, Geneviève, De Nardo, Dominic, Rootes, Christina L, Ullah, Tomalika R, Al-Asmari, Sumaiah S, Balka, Katherine R, Li, Hong-Mei, Quinn, Kylie M, Moghaddas, Fiona, Chappaz, Stephane, Kile, Benjamin T, Morand, Eric F, Masters, Seth L, Stewart, Cameron R, Williams, Bryan R G, Gantier, Michael P
Published in mBio (28.01.2020)
Published in mBio (28.01.2020)
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Journal Article
Discordance in STING-Induced Activation and Cell Death Between Mouse and Human Dendritic Cell Populations
Pang, Ee Shan, Daraj, Ghazal, Balka, Katherine R, De Nardo, Dominic, Macri, Christophe, Hochrein, Hubertus, Masterman, Kelly-Anne, Tan, Peck S, Shoppee, Angus, Magill, Zoe, Jahan, Nazneen, Bafit, Mariam, Zhan, Yifan, Kile, Benjamin T, Lawlor, Kate E, Radford, Kristen J, Wright, Mark D, O'Keeffe, Meredith
Published in Frontiers in immunology (25.02.2022)
Published in Frontiers in immunology (25.02.2022)
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Journal Article
Genistein Targets STING-Driven Antiviral Responses
Ullah, Tomalika R., Balka, Katherine R., Ambrose, Rebecca L., Pépin, Geneviève, Wilce, Matthew C. J., Wilce, Jacqueline A., Thomas, Belinda J., De Nardo, Dominic, Williams, Bryan R. G., Gantier, Michael P.
Published in mBio (30.08.2022)
Published in mBio (30.08.2022)
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Journal Article
IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
Venkatraman, Rajan, Balka, Katherine R., Wong, Wilson, Sivamani, Jananipriya, Magill, Zoe, Tullett, Kirsteen M., Lane, Rachael M., Saunders, Tahnee L., Tailler, Maximilien, Crack, Peter J., Wakim, Linda M., Lahoud, Mireille H., Lawlor, Kate E., Kile, Benjamin T., O’Keeffe, Meredith, De Nardo, Dominic
Published in iScience (20.09.2024)
Published in iScience (20.09.2024)
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Journal Article
Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling
De Nardo, Dominic, Balka, Katherine R., Cardona Gloria, Yamel, Rao, Vikram R., Latz, Eicke, Masters, Seth L.
Published in The Journal of biological chemistry (28.09.2018)
Published in The Journal of biological chemistry (28.09.2018)
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Journal Article
Termination of STING responses is mediated via ESCRT‐dependent degradation
Balka, Katherine R, Venkatraman, Rajan, Saunders, Tahnee L, Shoppee, Angus, Pang, Ee Shan, Magill, Zoe, Homman‐Ludiye, Jihane, Huang, Cheng, Lane, Rachael M, York, Harrison M, Tan, Peck, Schittenhelm, Ralf B, Arumugam, Senthil, Kile, Benjamin T, O'Keeffe, Meredith, De Nardo, Dominic
Published in The EMBO journal (15.06.2023)
Published in The EMBO journal (15.06.2023)
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Journal Article
Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy
Saunders, Tahnee L., Windley, Simon P., Gervinskas, Gediminas, Balka, Katherine R., Rowe, Caitlin, Lane, Rachael, Tailler, Maximilien, Nguyen, Thanh Ngoc, Ramm, Georg, Lazarou, Michael, De Nardo, Dominic, Kile, Benjamin T., McArthur, Kate
Published in Cell death and differentiation (01.03.2024)
Published in Cell death and differentiation (01.03.2024)
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Journal Article
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
Yu, Chien-Hsiung, Davidson, Sophia, Harapas, Cassandra R., Hilton, James B., Mlodzianoski, Michael J., Laohamonthonkul, Pawat, Louis, Cynthia, Low, Ronnie Ren Jie, Moecking, Jonas, De Nardo, Dominic, Balka, Katherine R., Calleja, Dale J., Moghaddas, Fiona, Ni, Erya, McLean, Catriona A., Samson, Andre L., Tyebji, Shiraz, Tonkin, Christopher J., Bye, Christopher R., Turner, Bradley J., Pepin, Genevieve, Gantier, Michael P., Rogers, Kelly L., McArthur, Kate, Crouch, Peter J., Masters, Seth L.
Published in Cell (29.10.2020)
Published in Cell (29.10.2020)
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Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24
Davidson, Sophia, Yu, Chien-Hsiung, Steiner, Annemarie, Ebstein, Frédéric, Baker, Paul J, Jarur-Chamy, Valentina, Hrovat Schaale, Katja, Laohamonthonkul, Pawat, Kong, Klara, Calleja, Dale J, Harapas, Cassandra R, Balka, Katherine R, Mitchell, Jacob, Jackson, Jacob T, Geoghegan, Niall D, Moghaddas, Fiona, Rogers, Kelly L, Mayer-Barber, Katrin D, De Jesus, Adriana A, De Nardo, Dominic, Kile, Benjamin T, Sadler, Anthony J, Poli, M Cecilia, Krüger, Elke, Goldbach Mansky, Raphaela, Masters, Seth L
Published in Science immunology (11.02.2022)
Published in Science immunology (11.02.2022)
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Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection
Ullah, Tomalika R., Johansen, Matt D., Balka, Katherine R., Ambrose, Rebecca L., Gearing, Linden J., Roest, James, Vivian, Julian P., Sapkota, Sunil, Jayasekara, W. Samantha N., Wenholz, Daniel S., Aldilla, Vina R., Zeng, Jun, Miemczyk, Stefan, Nguyen, Duc H., Hansbro, Nicole G., Venkatraman, Rajan, Kang, Jung Hee, Pang, Ee Shan, Thomas, Belinda J., Alharbi, Arwaf S., Rezwan, Refaya, O’Keeffe, Meredith, Donald, William A., Ellyard, Julia I., Wong, Wilson, Kumar, Naresh, Kile, Benjamin T., Vinuesa, Carola G., Kelly, Graham E., Laczka, Olivier F., Hansbro, Philip M., De Nardo, Dominic, Gantier, Michael P.
Published in Nature communications (18.09.2023)
Published in Nature communications (18.09.2023)
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