Myelodysplastic syndrome patient-derived xenografts: from no options to many
Côme, Christophe, Balhuizen, Alexander, Bonnet, Dominique, Porse, Bo T
Published in Haematologica (Roma) (01.04.2020)
Published in Haematologica (Roma) (01.04.2020)
Get full text
Journal Article
Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa
Demine, Stéphane, Balhuizen, Alexander, Debaille, Vinciane, Joosten, Lieke, Fereau, Maïté, Chilla, Satya Narayana Murthy, Millard, Isabelle, Scharfmann, Raphaël, Egrise, Dominique, Goldman, Serge, Marchetti, Piero, Gotthardt, Martin, Laurent, Sophie, Burtea, Carmen, Eizirik, Decio L
Published in Molecules (Basel, Switzerland) (21.08.2018)
Published in Molecules (Basel, Switzerland) (21.08.2018)
Get full text
Journal Article
The Crystal Structure of Thermotoga maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site
Aurelius, Oskar, Johansson, Renzo, Bågenholm, Viktoria, Lundin, Daniel, Tholander, Fredrik, Balhuizen, Alexander, Beck, Tobias, Sahlin, Margareta, Sjöberg, Britt-Marie, Mulliez, Etienne, Logan, Derek T
Published in PloS one (06.07.2015)
Published in PloS one (06.07.2015)
Get full text
Journal Article
Therapeutic Potential of an Immune-Modulatory Vaccination Targeting Myeloid-Derived Suppressor Cells in Myelodysplastic Syndrome
Bentivegna, Sofia, Holmstrøm, Morten, Balhuizen, Alexander, Almosailleakh, Marwa, Perez-Penco, Maria, Porse, Bo, Andersen, Mads Hald, Grønbæk, Kirsten
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
Get full text
Journal Article
Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice
Balhuizen, Alexander, Kumar, Rajesh, Amisten, Stefan, Lundquist, Ingmar, Salehi, Albert
Published in Molecular and cellular endocrinology (14.05.2010)
Published in Molecular and cellular endocrinology (14.05.2010)
Get full text
Journal Article
Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans
Bennet, Hedvig, Mollet, Inês G., Balhuizen, Alexander, Medina, Anya, Nagorny, Cecilia, Bagge, Annika, Fadista, Joao, Ottosson-Laakso, Emilia, Vikman, Petter, Dekker-Nitert, Marloes, Eliasson, Lena, Wierup, Nils, Artner, Isabella, Fex, Malin
Published in Diabetologia (01.04.2016)
Published in Diabetologia (01.04.2016)
Get full text
Journal Article
Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells
Brozzi, Flora, Gerlo, Sarah, Grieco, Fabio Arturo, Juusola, Matilda, Balhuizen, Alexander, Lievens, Sam, Gysemans, Conny, Bugliani, Marco, Mathieu, Chantal, Marchetti, Piero, Tavernier, Jan, Eizirik, Décio L.
Published in The Journal of biological chemistry (03.06.2016)
Published in The Journal of biological chemistry (03.06.2016)
Get full text
Journal Article
A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells
Balhuizen, Alexander, Massa, Sam, Mathijs, Iris, Turatsinze, Jean-Valery, De Vos, Jens, Demine, Stéphane, Xavier, Catarina, Villate, Olatz, Millard, Isabelle, Egrise, Dominique, Capito, Carmen, Scharfmann, Raphaël, In’t Veld, Pieter, Marchetti, Piero, Muyldermans, Serge, Goldman, Serge, Lahoutte, Tony, Bouwens, Luc, Eizirik, Decio L., Devoogdt, Nick
Published in Scientific reports (09.11.2017)
Published in Scientific reports (09.11.2017)
Get full text
Journal Article
Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes
Bennet, H., Balhuizen, A., Medina, A., Dekker Nitert, M., Ottosson Laakso, E., Essén, S., Spégel, P., Storm, P., Krus, U., Wierup, N., Fex, M.
Published in Peptides (New York, N.Y. : 1980) (01.09.2015)
Published in Peptides (New York, N.Y. : 1980) (01.09.2015)
Get full text
Journal Article
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes
Trempenau, Mette Louise, Schuster, Mikkel Bruhn, Pundhir, Sachin, Pereira, Mafalda Araujo, Kalvisa, Adrija, Tapia, Marta, Su, Jinyu, Ge, Ying, de Boer, Bauke, Balhuizen, Alexander, Bagger, Frederik Otzen, Shliaha, Pavel, Sroczynska, Patrycja, Walfridsson, Julian, Grønbæk, Kirsten, Theilgaard-Mönch, Kim, Jensen, Ole N., Helin, Kristian, Porse, Bo T.
Published in Leukemia (01.03.2023)
Published in Leukemia (01.03.2023)
Get full text
Journal Article
Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats
Medina, Anya, Parween, Saba, Ullsten, Sara, Vishnu, Neelanjan, Siu, Yuk Ting, Quach, My, Bennet, Hedvig, Balhuizen, Alexander, Åkesson, Lina, Wierup, Nils, Carlsson, Per Ola, Ahlgren, Ulf, Lernmark, Åke, Fex, Malin
Published in Diabetologia (01.04.2018)
Published in Diabetologia (01.04.2018)
Get full text
Journal Article
Autoimmunity against INS-IGF2 Protein Expressed in Human Pancreatic Islets
Kanatsuna, Norio, Taneera, Jalal, Vaziri-Sani, Fariba, Wierup, Nils, Larsson, Helena Elding, Delli, Ahmed, Skärstrand, Hanna, Balhuizen, Alexander, Bennet, Hedvig, Steiner, Donald F., Törn, Carina, Fex, Malin, Lernmark, Åke
Published in The Journal of biological chemistry (04.10.2013)
Published in The Journal of biological chemistry (04.10.2013)
Get full text
Journal Article
Strain Differences Determine the Suitability of Animal Models for Noninvasive In Vivo Beta Cell Mass Determination with Radiolabeled Exendin
Willekens, Stefanie M. A., Joosten, Lieke, Boerman, Otto C., Balhuizen, Alexander, Eizirik, Decio L., Gotthardt, Martin, Brom, Maarten
Published in Molecular imaging and biology (01.10.2016)
Published in Molecular imaging and biology (01.10.2016)
Get full text
Journal Article
Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
LYSSENKO, Valeriya, ELIASSON, Lena, TANEERA, Jalal, BALHUIZEN, Alexander, HANSSON, Ola, OSMARK, Peter, DUNER, Pontus, BRØNS, Charlotte, STANCAKOVA, Alena, KUUSISTO, Johanna, BUGLIANI, Marco, SAXENA, Richa, KOTOVA, Olga, AHLQVIST, Emma, KIEFFER, Timothy J, TUOMI, Tiinamaija, ISOMAA, Bo, MELANDER, Olle, SONESTEDT, Emily, ORHO-MELANDER, Marju, NILSSON, Peter, BONETTI, Sara, BONADONNA, Riccardo, PILGAARD, Kasper, MICCOLI, Roberto, DELPRATO, Stefano, MARCHETTI, Piero, MADSBAD, Sten, POULSEN, Pernille, VAAG, Allan, LAAKSO, Markku, GOMEZ, Maria F, GROOP, Leif, WIERUP, Nils, SALEHI, Albert, WENDT, Anna, JONSSON, Anna, DE MARINIS, Yang Z, BERGLUND, Lisa M
Published in Diabetes (New York, N.Y.) (01.09.2011)
Published in Diabetes (New York, N.Y.) (01.09.2011)
Get full text
Journal Article
A Common Variant in TFB1M Is Associated with Reduced Insulin Secretion and Increased Future Risk of Type 2 Diabetes
Koeck, Thomas, Olsson, Anders H., Nitert, Marloes Dekker, Sharoyko, Vladimir V., Ladenvall, Claes, Kotova, Olga, Reiling, Erwin, Rönn, Tina, Parikh, Hemang, Taneera, Jalal, Eriksson, Johan G., Metodiev, Metodi D., Larsson, Nils-Göran, Balhuizen, Alexander, Luthman, Holger, Stančáková, Alena, Kuusisto, Johanna, Laakso, Markku, Poulsen, Pernille, Vaag, Allan, Groop, Leif, Lyssenko, Valeriya, Mulder, Hindrik, Ling, Charlotte
Published in Cell metabolism (05.01.2011)
Published in Cell metabolism (05.01.2011)
Get full text
Journal Article
What can we learn about nucleotide metabolism from a thermophilic anaerobic ribonucleotide reductase?
Aurelius, Oskar, Johansson, Renzo, Bågenholm, Viktoria, Lundin, Daniel, Tholander, Fredrik, Balhuizen, Alexander, Beck, Tobias, Sahlin, Margareta, Emanuelsson, Cecilia, Sjöberg, Britt-Marie, Mulliez, Etienne, Logan, Derek T.
Published in Acta crystallographica. Section A, Foundations and advances (23.08.2015)
Published in Acta crystallographica. Section A, Foundations and advances (23.08.2015)
Get full text
Journal Article
The first ribonucleotide reductase without an activating radical cysteine
Aurelius, Oskar, Johansson, Renzo, Bågenholm, Viktoria, Lundin, Daniel, Balhuizen, Alexander, Beck, Tobias, Sjöberg, Britt-Marie, Mulliez, Etienne, Logan, Derek
Published in Acta crystallographica. Section A, Foundations and advances (05.08.2014)
Published in Acta crystallographica. Section A, Foundations and advances (05.08.2014)
Get full text
Journal Article
Autoimmunity against INS-IGF2 expressed in human pancreatic islets
Kanatsuna, Norio, Taneera, Jalal, Vaziri Sani, Fariba, Wierup, Nils, Larsson, Helena, Delli, Ahmed, Skärstrand, Hanna, Balhuizen, Alexander, Bennet, Hedvig, Steiner, Donald F, Törn, Carina, Fex, Malin, Lernmark, Åke
Published in The Journal of biological chemistry (2013)
Published in The Journal of biological chemistry (2013)
Get full text
Journal Article