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Egan, William J, Merz, Kenneth M, Baldwin, John J
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Published in Journal of medicinal chemistry (19.10.2000)
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Allosteric Inhibitors of Inducible Nitric Oxide Synthase Dimerization Discovered via Combinatorial Chemistry
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Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2000)
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Optimization of orally bioavailable alkyl amine renin inhibitors
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Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
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3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists
Biju, Purakkattle, Taveras, Arthur, Yu, Younong, Zheng, Junying, Chao, Jianhua, Rindgen, Diane, Jakway, James, Hipkin, R. William, Fossetta, James, Fan, Xuedong, Fine, Jay, Qiu, Hongchen, Merritt, J. Robert, Baldwin, John J.
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists
Chiba, Jun, Takayama, Gensuke, Takashi, Tohru, Yokoyama, Mika, Nakayama, Atsushi, Baldwin, John J., McDonald, Edward, Moriarty, Kevin J., Sarko, Christopher R., Saionz, Kurt W., Swanson, Robert, Hussain, Zahid, Wong, Angela, Machinaga, Nobuo
Published in Bioorganic & medicinal chemistry (15.04.2006)
Published in Bioorganic & medicinal chemistry (15.04.2006)
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Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist
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Published in Bioorganic & medicinal chemistry letters (03.01.2005)
Published in Bioorganic & medicinal chemistry letters (03.01.2005)
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On the use of the O-methylmandelate ester for establishment of absolute configuration of secondary alcohols
Trost, Barry M, Belletire, John L, Godleski, Stephen, McDougal, Patrick G, Balkovec, James M, Baldwin, John J, Christy, Marcia E, Ponticello, Gerald S, Varga, Sandor L, Springer, James P
Published in Journal of organic chemistry (01.06.1986)
Published in Journal of organic chemistry (01.06.1986)
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An electronic environment and contact direction sensitive scoring function for predicting affinities of protein–ligand complexes in Contour
Lindblom, Peter R., Wu, Guosheng, Liu, Zhijie, Jim, Kam-Chuen, Baldwin, John J., Gregg, Richard E., Claremon, David A., Singh, Suresh B.
Published in Journal of molecular graphics & modelling (01.09.2014)
Published in Journal of molecular graphics & modelling (01.09.2014)
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Thienothiopyran-2-sulfonamides: novel topically active carbonic anhydrase inhibitors for the treatment of glaucoma
Baldwin, John J, Ponticello, Gerald S, Anderson, Paul S, Christy, Marcia E, Murcko, Mark A, Randall, William C, Schwam, Harvey, Sugrue, Michael F, Gautheron, Pierre
Published in Journal of medicinal chemistry (01.12.1989)
Published in Journal of medicinal chemistry (01.12.1989)
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Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility
Jia, Lanqi, Simpson, Robert D, Yuan, Jing, Xu, Zhenrong, Zhao, Wei, Cacatian, Salvacion, Tice, Colin M, Guo, Joan, Ishchenko, Alexey, Singh, Suresh B, Wu, Zhongren, McKeever, Brian M, Bukhtiyarov, Yuri, Johnson, Judith A, Doe, Christopher P, Harrison, Richard K, McGeehan, Gerard M, Dillard, Lawrence W, Baldwin, John J, Claremon, David A
Published in ACS medicinal chemistry letters (13.10.2011)
Published in ACS medicinal chemistry letters (13.10.2011)
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III. Identification of novel CXCR3 chemokine receptor antagonists with a pyrazinyl–piperazinyl–piperidine scaffold
Kim, Seong Heon, Anilkumar, Gopinadhan N., Zawacki, Lisa Guise, Zeng, Qingbei, Yang, De-Yi, Shao, Yuefei, Dong, Guizhen, Xu, Xiaolian, Yu, Wensheng, Jiang, Yueheng, Jenh, Chung-Her, Hall, James W., Carroll, Carolyn DiIanni, Hobbs, Doug W., Baldwin, John J., McGuinness, Brian F., Rosenblum, Stuart B., Kozlowski, Joseph A., Shankar, Bandarpalle B., Shih, Neng-Yang
Published in Bioorganic & medicinal chemistry letters (01.12.2011)
Published in Bioorganic & medicinal chemistry letters (01.12.2011)
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Synthesis and structure–activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists
Merritt, J. Robert, Rokosz, Laura L., Nelson, Kingsley H., Kaiser, Bernd, Wang, Wei, Stauffer, Tara M., Ozgur, Lynne E., Schilling, Adriane, Li, Ge, Baldwin, John J., Taveras, Arthur G., Dwyer, Michael P., Chao, Jianping
Published in Bioorganic & medicinal chemistry letters (01.08.2006)
Published in Bioorganic & medicinal chemistry letters (01.08.2006)
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Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket
Yuan, Jing, Simpson, Robert D., Zhao, Wei, Tice, Colin M., Xu, Zhenrong, Cacatian, Salvacion, Jia, Lanqi, Flaherty, Patrick T., Guo, Joan, Ishchenko, Alexey, Wu, Zhongren, McKeever, Brian M., Scott, Boyd B., Bukhtiyarov, Yuri, Berbaum, Jennifer, Panemangalore, Reshma, Bentley, Ross, Doe, Christopher P., Harrison, Richard K., McGeehan, Gerard M., Singh, Suresh B., Dillard, Lawrence W., Baldwin, John J., Claremon, David A.
Published in Bioorganic & medicinal chemistry letters (15.08.2011)
Published in Bioorganic & medicinal chemistry letters (15.08.2011)
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Design and optimization of renin inhibitors: Orally bioavailable alkyl amines
Tice, Colin M., Xu, Zhenrong, Yuan, Jing, Simpson, Robert D., Cacatian, Salvacion T., Flaherty, Patrick T., Zhao, Wei, Guo, Joan, Ishchenko, Alexey, Singh, Suresh B., Wu, Zhongren, Scott, Boyd B., Bukhtiyarov, Yuri, Berbaum, Jennifer, Mason, Jennifer, Panemangalore, Reshma, Cappiello, Maria Grazia, Müller, Dominik, Harrison, Richard K., McGeehan, Gerard M., Dillard, Lawrence W., Baldwin, John J., Claremon, David A.
Published in Bioorganic & medicinal chemistry (01.07.2009)
Published in Bioorganic & medicinal chemistry (01.07.2009)
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Surfing the piperazine core of tricyclic farnesyltransferase inhibitors
Rokosz, Laura L., Huang, Chia-Yu, Reader, John C., Stauffer, Tara M., Chelsky, Daniel, Sigal, Nolan H., Ganguly, Ashit K., Baldwin, John J.
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
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Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists
Cole, Andrew G., Metzger, Axel, Brescia, Marc-Raleigh, Qin, Lan-Ying, Appell, Kenneth C., Brain, Christopher T., Hallett, Allan, Ganju, Pam, Denholm, Alastair A., Wareing, James R., Ritchie, Timothy J., Drake, Gillian M., Bevan, Stuart J., MacGloinn, Aisling, McBryde, Andrew, Patel, Viral, Oakley, Paul J., Nunez, Ximena, Gstach, Hubert, Schneider, Peter, Baldwin, John J., Dolle, Roland E., McDonald, Edward, Henderson, Ian
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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