GSK-3β Allosteric Inhibition: A Dead End or a New Pharmacological Frontier?
Balboni, Beatrice, Masi, Mirco, Rocchia, Walter, Girotto, Stefania, Cavalli, Andrea
Published in International journal of molecular sciences (19.04.2023)
Published in International journal of molecular sciences (19.04.2023)
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Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives
Barbieri, Federica, Bosio, Alessia Graziana, Pattarozzi, Alessandra, Tonelli, Michele, Bajetto, Adriana, Verduci, Ivan, Cianci, Francesca, Cannavale, Gaetano, Palloni, Luca M G, Francesconi, Valeria, Thellung, Stefano, Fiaschi, Pietro, Mazzetti, Samanta, Schenone, Silvia, Balboni, Beatrice, Girotto, Stefania, Malatesta, Paolo, Daga, Antonio, Zona, Gianluigi, Mazzanti, Michele, Florio, Tullio
Published in Journal of experimental & clinical cancer research (08.02.2022)
Published in Journal of experimental & clinical cancer research (08.02.2022)
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Identification of Novel GSK-3β Hits Using Competitive Biophysical Assays
Balboni, Beatrice, Tripathi, Shailesh Kumar, Veronesi, Marina, Russo, Debora, Penna, Ilaria, Giabbai, Barbara, Bandiera, Tiziano, Storici, Paola, Girotto, Stefania, Cavalli, Andrea
Published in International journal of molecular sciences (31.03.2022)
Published in International journal of molecular sciences (31.03.2022)
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GSK3β as a novel promising target to overcome chemoresistance in pancreatic cancer
Pecoraro, Camilla, Faggion, Beatrice, Balboni, Beatrice, Carbone, Daniela, Peters, Godefridus J., Diana, Patrizia, Assaraf, Yehuda G., Giovannetti, Elisa
Published in Drug resistance updates (01.09.2021)
Published in Drug resistance updates (01.09.2021)
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Novel Insights into RAD52's Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies
Balboni, Beatrice, Rinaldi, Francesco, Previtali, Viola, Ciamarone, Andrea, Girotto, Stefania, Cavalli, Andrea
Published in Cancers (17.03.2023)
Published in Cancers (17.03.2023)
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Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer
Rinaldi, Francesco, Schipani, Fabrizio, Balboni, Beatrice, Catalano, Federico, Marotta, Roberto, Myers, Samuel H., Previtali, Viola, Veronesi, Marina, Scietti, Luigi, Cecatiello, Valentina, Pasqualato, Sebastiano, Ortega, Jose Antonio, Girotto, Stefania, Cavalli, Andrea
Published in Angewandte Chemie International Edition (18.12.2023)
Published in Angewandte Chemie International Edition (18.12.2023)
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Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5
Brusa, Irene, Sondo, Elvira, Pesce, Emanuela, Tomati, Valeria, Gioia, Dario, Falchi, Federico, Balboni, Beatrice, Ortega Martínez, Jose Antonio, Veronesi, Marina, Romeo, Elisa, Margaroli, Natasha, Recanatini, Maurizio, Girotto, Stefania, Pedemonte, Nicoletta, Roberti, Marinella, Cavalli, Andrea
Published in Journal of medicinal chemistry (27.07.2023)
Published in Journal of medicinal chemistry (27.07.2023)
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ARN25068, a versatile starting point towards triple GSK-3β/FYN/DYRK1A inhibitors to tackle tau-related neurological disorders
Demuro, Stefania, Sauvey, Conall, Tripathi, Shailesh K., Di Martino, Rita M.C., Shi, Da, Ortega, Jose A., Russo, Debora, Balboni, Beatrice, Giabbai, Barbara, Storici, Paola, Girotto, Stefania, Abagyan, Ruben, Cavalli, Andrea
Published in European journal of medicinal chemistry (05.02.2022)
Published in European journal of medicinal chemistry (05.02.2022)
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Identification of RAD51–BRCA2 Inhibitors Using N‑Acylhydrazone-Based Dynamic Combinatorial Chemistry
Bagnolini, Greta, Balboni, Beatrice, Schipani, Fabrizio, Gioia, Dario, Veronesi, Marina, De Franco, Francesca, Kaya, Cansu, Jumde, Ravindra P., Ortega, Jose Antonio, Girotto, Stefania, Hirsch, Anna K. H., Roberti, Marinella, Cavalli, Andrea
Published in ACS medicinal chemistry letters (11.08.2022)
Published in ACS medicinal chemistry letters (11.08.2022)
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RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment
Balboni, Beatrice, El Hassouni, Btissame, Honeywell, Richard J., Sarkisjan, Dzjemma, Giovannetti, Elisa, Poore, Julie, Heaton, Callie, Peterson, Christine, Benaim, Ely, Lee, Young B., Kim, Deog J., Peters, Godefridus J.
Published in Expert opinion on investigational drugs (03.04.2019)
Published in Expert opinion on investigational drugs (03.04.2019)
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Abstract 1267: Unusual mechanism of resistance to the novel cytidine analog fluorocyclopentenylcytosine (RX-3117)
Peters, Godefridus J., Sarkisjan, Dzjemma, Hassouni, Btissame El, Honeywell, Richard J., Julsing, Joris R., Balboni, Beatrice, Klerk, Daniel J. De, Zekanovic, Safet, Smid, Kees, Giovannetti, Elisa, Lee, Young B., Kim, Deog J.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer
Rinaldi, Francesco, Schipani, Fabrizio, Balboni, Beatrice, Catalano, Federico, Marotta, Roberto, Myers, Samuel H., Previtali, Viola, Veronesi, Marina, Scietti, Luigi, Cecatiello, Valentina, Pasqualato, Sebastiano, Ortega, Jose Antonio, Girotto, Stefania, Cavalli, Andrea
Published in Angewandte Chemie (18.12.2023)
Published in Angewandte Chemie (18.12.2023)
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Abstract 903: Metformin antitumoral activity is exclusively mediated by the membrane functional expression of the Chloride Intracellular Channel 1 in glioblastoma stem cells
Verduci, Ivan, Cianci, Francesca, Cazzoli, Riccardo, Cannavale, Gaetano, Castiglione, Stefania, Ranucci, Matteo, Palloni, Luca, Balboni, Beatrice, Faletti, Stefania, Girotto, Stefania, Pelicci, Giuliana, Minucci, Saverio, Fantin, Alessandro, Florio, Tullio, Mazzanti, Michele
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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