A new and efficient preparation of 2-aminothiazole-5-carbamides: applications to the synthesis of the anti-cancer drug dasatinib
Chen, Bang-Chi, Zhao, Rulin, Wang, Bei, Droghini, Roberto, Lajeunesse, Jean, Sirard, Pierre, Endo, Masaki, Balasubramanian, Balu, Barrish, Joel C.
Published in ARKIVOC (01.01.2010)
Published in ARKIVOC (01.01.2010)
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Preparation of Monofluorophenols via the Reaction of Difluorobenzene Derivatives with Potassium Trimethylsilanoate
Li, Jianqing, Smith, Daniel, Qiao, Jennifer X., Huang, Stella, Krishnananthan, Subramaniam, Wong, Henry S., Salvati, Mark E., Balasubramanian, Balu N., Chen, Bang-Chi
Published in Synlett (01.03.2009)
Published in Synlett (01.03.2009)
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Identification and Characterization of Compounds That Potentiate NT-3-Mediated Trk Receptor Activity
Lewis, Martin A, Hunihan, Lisa, Franco, Diana, Robertson, Barbara, Palmer, Jane, Laurent, Denis R St, Balasubramanian, Balu N, Li, Yi, Westphal, Ryan S
Published in Molecular pharmacology (01.04.2006)
Published in Molecular pharmacology (01.04.2006)
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Discovery of a Fluoroindolo[2,3-a]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11
Saulnier, Mark G, Balasubramanian, Balu N, Long, Byron H, Frennesson, David B, Ruediger, Edward, Zimmermann, Kurt, Eummer, Jeffrey T, St. Laurent, Denis R, Stoffan, Karen M, Naidu, B. Narasimhulu, Mahler, Mikael, Beaulieu, Francis, Bachand, Carol, Lee, Frank Y, Fairchild, Craig R, Stadnick, Linda K, Rose, William C, Solomon, Carola, Wong, Henry, Martel, Alain, Wright, John J, Kramer, Robert, Langley, David R, Vyas, Dolatrai M
Published in Journal of medicinal chemistry (07.04.2005)
Published in Journal of medicinal chemistry (07.04.2005)
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Sordaricin antifungal agents
Quesnelle, Claude A, Gill, Patrice, Dodier, Marco, St. Laurent, Denis, Serrano-Wu, Michael, Marinier, Anne, Martel, Alain, Mazzucco, Charles E, Stickle, Terry M, Barrett, John F, Vyas, Dolatrai M, Balasubramanian, Balu N
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
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Improved procedure for the preparation of 7-methoxy-2-methyl-1-(2-morpholinoethyl)-1H-indole-3-carboxylic acid, key intermediate in the synthesis of novel 3-amidoindole and indolopyridone cannabinoid ligands
Zhao, Rulin, Wang, Bei, Wu, Hong, Hynes, John, Leftheris, Katerina, Balasubramanian, Balu, Barrish, Joel C., Chen, Bang-Chi
Published in ARKIVOC (01.01.2010)
Published in ARKIVOC (01.01.2010)
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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model
Balasubramanian, Balu N, St. Laurent, Denis R, Saulnier, Mark G, Long, Byron H, Bachand, Carol, Beaulieu, Francis, Clarke, Wendy, Deshpande, Milind, Eummer, Jeffrey, Fairchild, Craig R, Frennesson, David B, Kramer, Robert, Lee, Frank Y, Mahler, Mikael, Martel, Alain, Naidu, B. Narasimhulu, Rose, William C, Russell, John, Ruediger, Edward, Solomon, Carola, Stoffan, Karen M, Wong, Henry, Zimmermann, Kurt, Vyas, Dolatrai M
Published in Journal of medicinal chemistry (25.03.2004)
Published in Journal of medicinal chemistry (25.03.2004)
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Novel fluoro-substituted camptothecins : in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization
ROSE, William C, MARATHE, Punit H, JANG, Graham R, MONTICELLO, Thomas M, BALASUBRAMANIAN, Balu N, LONG, Byron, FAIRCHILD, Craig R, WALL, Monroe E, WANI, Mansukh C
Published in Cancer chemotherapy and pharmacology (01.07.2006)
Published in Cancer chemotherapy and pharmacology (01.07.2006)
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Sordarin Oxazepine Derivatives as Potent Antifungal Agents
Serrano-Wu, Michael H., St. Laurent, Denis R., Chen, Yijun, Huang, Stella, Lam, Kin-Ray, Matson, James A., Mazzucco, Charles E., Stickle, Terry M., Tully, Thomas P., Wong, Henry S., Vyas, Dolatrai M., Balasubramanian, Balu N.
Published in Bioorganic & medicinal chemistry letters (07.10.2002)
Published in Bioorganic & medicinal chemistry letters (07.10.2002)
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A new efficient synthesis of N-(2-(2-(3-methoxy-4-(oxazol-5-yl)phenylamino)oxazol-5-yl)phenyl)-N-methyl-2-morpholinoacetamide (BMS-337197), A novel IMPDH inhibitor
Zhao, Rulin, Chen, Bang-Chi, Bednarz, Mark S., Wang, Bei, Skoumbourdis, Amanda P., Sundeen, Joseph E., Dhar, T. G. Murali, Iwanowicz, Edwin J., Balasubramanian, Balu, Barrish, Joel C.
Published in ARKIVOC (04.03.2007)
Published in ARKIVOC (04.03.2007)
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A new efficient synthesis of 5-aryloxazoles from arylidene diacetates and application to the preparation of BMS-337197, a novel IMPDH inhibitor
Chen, BC, Bednarz, MS, Zhang, HP, Zhao, RL, Dhar, TGM, Balasubramanian, B, Barrish, JC
Published in Heterocycles (01.01.2006)
Published in Heterocycles (01.01.2006)
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Identification of a broad-Spectrum azasordarin with improved pharmacokinetic properties
Serrano-Wu, Michael H., Laurent, Denis R.St, Carroll, Tina M., Dodier, Marco, Gao, Qi, Gill, Patrice, Quesnelle, Claude, Marinier, Anne, Mazzucco, Charles E., Regueiro-Ren, Alicia, Stickle, Terry M., Wu, Dedong, Yang, Hyekyung, Yang, Zheng, Zheng, Ming, Zoeckler, Mary E., Vyas, Dolatrai M., Balasubramanian, Balu N.
Published in Bioorganic & medicinal chemistry letters (17.04.2003)
Published in Bioorganic & medicinal chemistry letters (17.04.2003)
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Core-modified sordaricin derivatives: Synthesis and antifungal activity
Regueiro-Ren, Alicia, Carroll, Tina M., Chen, Yijun, Matson, James A., Huang, Stella, Mazzucco, Charles E., Stickle, Terry M., Vyas, Dolatrai M., Balasubramanian, Balu N.
Published in Bioorganic & medicinal chemistry letters (02.12.2002)
Published in Bioorganic & medicinal chemistry letters (02.12.2002)
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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β-d-glucopyranosyl]-5H,13H-benzo[b]thienyl[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model
Balasubramanian, Balu N, St. Laurent, Denis R, Saulnier, Mark G, Long, Byron H, Bachand, Carol, Beaulieu, Francis, Clarke, Wendy, Deshpande, Milind, Eummer, Jeffrey, Fairchild, Craig R, Frennesson, David B, Kramer, Robert, Lee, Frank Y, Mahler, Mikael, Martel, Alain, Naidu, B. Narasimhulu, Rose, William C, Russell, John, Ruediger, Edward, Solomon, Carola, Stoffan, Karen M, Wong, Henry, Wright, John J, Zimmermann, Kurt, Vyas, Dolatrai M
Published in Journal of medicinal chemistry (27.01.2005)
Published in Journal of medicinal chemistry (27.01.2005)
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Mild deprotection of 2-(trimethylsilyl)ethyl esters
Serrano-Wu, Michael H, Regueiro-Ren, Alicia, St. Laurent, Denis R, Carroll, Tina M, Balasubramanian, Balu N
Published in Tetrahedron letters (03.12.2001)
Published in Tetrahedron letters (03.12.2001)
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Synthesis and characterization of tritium labeled N -(( R )-1-(( S )-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-methyl-1-oxobutan-2-yl)-3-sulfamoylbenzamide: Tritium Labeling and Characterization of a CCR1 Antagonist
Hong, Yang, Hynes, John, Tian, Yuan, Balasubramanian, Balu, Bonacorsi, Samuel
Published in Journal of labelled compounds & radiopharmaceuticals (01.08.2015)
Published in Journal of labelled compounds & radiopharmaceuticals (01.08.2015)
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