Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
Zhu, Zhihong, Zhang, Futao, Hu, Han, Bakshi, Andrew, Robinson, Matthew R, Powell, Joseph E, Montgomery, Grant W, Goddard, Michael E, Wray, Naomi R, Visscher, Peter M, Yang, Jian
Published in Nature genetics (01.05.2016)
Published in Nature genetics (01.05.2016)
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Journal Article
The Genetic Architecture of Gene Expression in Peripheral Blood
Lloyd-Jones, Luke R., Holloway, Alexander, McRae, Allan, Yang, Jian, Small, Kerrin, Zhao, Jing, Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Dermitzakis, Manolis, Gibson, Greg, Spector, Tim, Montgomery, Grant, Esko, Tonu, Visscher, Peter M., Powell, Joseph E.
Published in American journal of human genetics (02.02.2017)
Published in American journal of human genetics (02.02.2017)
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Journal Article
Genetic signatures of high-altitude adaptation in Tibetans
Yang, Jian, Jin, Zi-Bing, Chen, Jie, Huang, Xiu-Feng, Li, Xiao-Man, Liang, Yuan-Bo, Mao, Jian-Yang, Chen, Xin, Zheng, Zhili, Bakshi, Andrew, Zheng, Dong-Dong, Zheng, Mei-Qin, Wray, Naomi R., Visscher, Peter M., Lu, Fan, Qu, Jia
Published in Proceedings of the National Academy of Sciences - PNAS (18.04.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (18.04.2017)
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Journal Article
Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits
Bakshi, Andrew, Zhu, Zhihong, Vinkhuyzen, Anna A. E., Hill, W. David, McRae, Allan F., Visscher, Peter M., Yang, Jian
Published in Scientific reports (08.09.2016)
Published in Scientific reports (08.09.2016)
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Journal Article
Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits
Zhu, Zhihong, Bakshi, Andrew, Vinkhuyzen, Anna A.E., Hemani, Gibran, Lee, Sang Hong, Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, Esko, Tonu, Milani, Lili, Mägi, Reedik, Metspalu, Andres, Hill, William G., Weir, Bruce S., Goddard, Michael E., Visscher, Peter M., Yang, Jian
Published in American journal of human genetics (05.03.2015)
Published in American journal of human genetics (05.03.2015)
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Journal Article
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology
Risbridger, Gail P., Clark, Ashlee K., Porter, Laura H., Toivanen, Roxanne, Bakshi, Andrew, Lister, Natalie L., Pook, David, Pezaro, Carmel J., Sandhu, Shahneen, Keerthikumar, Shivakumar, Quezada Urban, Rosalia, Papargiris, Melissa, Kraska, Jenna, Madsen, Heather B., Wang, Hong, Richards, Michelle G., Niranjan, Birunthi, O’Dea, Samantha, Teng, Linda, Wheelahan, William, Li, Zhuoer, Choo, Nicholas, Ouyang, John F., Thorne, Heather, Devereux, Lisa, Hicks, Rodney J., Sengupta, Shomik, Harewood, Laurence, Iddawala, Mahesh, Azad, Arun A., Goad, Jeremy, Grummet, Jeremy, Kourambas, John, Kwan, Edmond M., Moon, Daniel, Murphy, Declan G., Pedersen, John, Clouston, David, Norden, Sam, Ryan, Andrew, Furic, Luc, Goode, David L., Frydenberg, Mark, Lawrence, Mitchell G., Taylor, Renea A.
Published in Nature communications (19.08.2021)
Published in Nature communications (19.08.2021)
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Journal Article
Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy
Byars, Sean G, Huang, Qin Qin, Gray, Lesley-Ann, Bakshi, Andrew, Ripatti, Samuli, Abraham, Gad, Stearns, Stephen C, Inouye, Michael
Published in PLoS genetics (22.06.2017)
Published in PLoS genetics (22.06.2017)
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Neonatal genetics of gene expression reveal potential origins of autoimmune and allergic disease risk
Huang, Qin Qin, Tang, Howard H. F., Teo, Shu Mei, Mok, Danny, Ritchie, Scott C., Nath, Artika P., Brozynska, Marta, Salim, Agus, Bakshi, Andrew, Holt, Barbara J., Khor, Chiea Chuen, Sly, Peter D., Holt, Patrick G., Holt, Kathryn E., Inouye, Michael
Published in Nature communications (28.07.2020)
Published in Nature communications (28.07.2020)
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Journal Article
Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene
Yu, Chenglong, Bakshi, Andrew, Watts, Gerald F, Renton, Alan E, Fulton-Howard, Brian, Goate, Alison M, Natarajan, Pradeep, Chasman, Daniel I, Robman, Liubov, Woods, Robyn L, Guymer, Robyn, Wolfe, Rory, Thao, Le Thi Phuong, McNeil, John J, Tonkin, Andrew M, Nicholls, Stephen J, Lacaze, Paul
Published in Journal of the American Heart Association (07.11.2023)
Published in Journal of the American Heart Association (07.11.2023)
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Journal Article
Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women
Mehta, Divya, Tropf, Felix C, Gratten, Jacob, Bakshi, Andrew, Zhu, Zhihong, Bacanu, Silviu-Alin, Hemani, Gibran, Magnusson, Patrik K E, Barban, Nicola, Esko, Tõnu, Metspalu, Andres, Snieder, Harold, Mowry, Bryan J, Kendler, Kenneth S, Yang, Jian, Visscher, Peter M, McGrath, John J, Mills, Melinda C, Wray, Naomi R, Lee, S Hong, Andreassen, Ole A, Bramon, Elvira, Bruggeman, Richard, Buxbaum, Joseph D, Cairns, Murray J, Cantor, Rita M, Cloninger, C Robert, Cohen, David, Crespo-Facorro, Benedicto, Darvasi, Ariel, DeLisi, Lynn E, Dinan, Timothy, Djurovic, Srdjan, Donohoe, Gary, Drapeau, Elodie, Escott-Price, Valentina, Freimer, Nelson B, Georgieva, Lyudmila, de Haan, Lieuwe, Henskens, Frans A, Joa, Inge, Julià, Antonio, Khrunin, Andrey, Lerer, Bernard, Limborska, Svetlana, Loughland, Carmel M, Macek, Jr, Milan, Marsal, Sara, McCarley, Robert W, McIntosh, Andrew M, McQuillin, Andrew, Melegh, Bela, Michie, Patricia T, Morris, Derek W, Murphy, Kieran C, Myin-Germeys, Inez, Olincy, Ann, Van Os, Jim, Pantelis, Christos, Posthuma, Danielle, Quested, Digby, Schall, Ulrich, Scott, Rodney J, Seidman, Larry J, Toncheva, Draga, Tooney, Paul A, Waddington, John, Weinberger, Daniel R, Weiser, Mark, Wu, Jing Qin
Published in JAMA psychiatry (Chicago, Ill.) (01.05.2016)
Published in JAMA psychiatry (Chicago, Ill.) (01.05.2016)
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Journal Article
Establishing a cryopreservation protocol for patient‐derived xenografts of prostate cancer
Porter, Laura H., Lawrence, Mitchell G., Wang, Hong, Clark, Ashlee K, Bakshi, Andrew, Obinata, Daisuke, Goode, David, Papargiris, Melissa, MURAL, Clouston, David, Ryan, Andrew, Norden, Sam, Corey, Eva, Nelson, Peter S., Isaacs, John T., Grummet, Jeremy, Kourambas, John, Sandhu, Shahneen, Murphy, Declan G., Pook, David, Frydenberg, Mark, Taylor, Renea A., Risbridger, Gail P.
Published in The Prostate (01.08.2019)
Published in The Prostate (01.08.2019)
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Journal Article
A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells
Riaz, Moeen, Mattisson, Jonas, Polekhina, Galina, Bakshi, Andrew, Halvardson, Jonatan, Danielsson, Marcus, Ameur, Adam, McNeil, John, Forsberg, Lars A, Lacaze, Paul
Published in Cell & bioscience (12.12.2021)
Published in Cell & bioscience (12.12.2021)
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Journal Article
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index
Yang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A.E., Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, Esko, Tonu, Milani, Lili, Mägi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K.E., Pedersen, Nancy L., Ingelsson, Erik, Visscher, Peter M.
Published in Human molecular genetics (20.12.2015)
Published in Human molecular genetics (20.12.2015)
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Journal Article
Hidden heritability due to heterogeneity across seven populations
Tropf, Felix C., Lee, S. Hong, Verweij, Renske M., Stulp, Gert, van der Most, Peter J., de Vlaming, Ronald, Bakshi, Andrew, Briley, Daniel A., Rahal, Charles, Hellpap, Robert, Iliadou, Anastasia N., Esko, Tõnu, Metspalu, Andres, Medland, Sarah E., Martin, Nicholas G., Barban, Nicola, Snieder, Harold, Robinson, Matthew R., Mills, Melinda C.
Published in Nature human behaviour (01.10.2017)
Published in Nature human behaviour (01.10.2017)
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Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Okbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hyeokmoon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Hicks, Barry, Tian, Chao, Hinds, David A., Ahlskog, Rafael, Magnusson, Patrik K. E., Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David J., Freese, Jeremy, Herd, Pamela, Watson, Chelsea, Jala, Jonathan, Conley, Dalton, Koellinger, Philipp D., Johannesson, Magnus, Laibson, David, Meyer, Michelle N., Lee, James J., Kong, Augustine, Yengo, Loic, Cesarini, David, Turley, Patrick, Visscher, Peter M., Beauchamp, Jonathan P., Benjamin, Daniel J., Young, Alexander I.
Published in Nature genetics (2022)
Published in Nature genetics (2022)
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Journal Article
Aspirin, Risk of Colorectal Cancer, & Genetic Risk—Reply
Bakshi, Andrew, Chan, Andrew T.
Published in Cancer prevention research (Philadelphia, Pa.) (04.10.2022)
Published in Cancer prevention research (Philadelphia, Pa.) (04.10.2022)
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Journal Article
Aspirin for Primary Prevention of Cardiovascular Events in Relation to Lipoprotein(a) Genotypes
Lacaze, Paul, Bakshi, Andrew, Riaz, Moeen, Polekhina, Galina, Owen, Alice, Bhatia, Harpreet S., Natarajan, Pradeep, Wolfe, Rory, Beilin, Lawrence, Nicholls, Stephen J., Watts, Gerald F., McNeil, John J., Tonkin, Andrew M., Tsimikas, Sotirios
Published in Journal of the American College of Cardiology (04.10.2022)
Published in Journal of the American College of Cardiology (04.10.2022)
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Journal Article
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Lee, James J., Wedow, Robbee, Okbay, Aysu, Kong, Edward, Maghzian, Omeed, Zacher, Meghan, Nguyen-Viet, Tuan Anh, Bowers, Peter, Sidorenko, Julia, Karlsson Linnér, Richard, Fontana, Mark Alan, Kundu, Tushar, Lee, Chanwook, Li, Hui, Li, Ruoxi, Royer, Rebecca, Timshel, Pascal N., Walters, Raymond K., Willoughby, Emily A., Yengo, Loïc, Alver, Maris, Bao, Yanchun, Clark, David W., Day, Felix R., Furlotte, Nicholas A., Joshi, Peter K., Kemper, Kathryn E., Kleinman, Aaron, Langenberg, Claudia, Mägi, Reedik, Trampush, Joey W., Verma, Shefali Setia, Wu, Yang, Lam, Max, Zhao, Jing Hua, Zheng, Zhili, Boardman, Jason D., Campbell, Harry, Freese, Jeremy, Harris, Kathleen Mullan, Hayward, Caroline, Herd, Pamela, Kumari, Meena, Lencz, Todd, Luan, Jian’an, Malhotra, Anil K., Metspalu, Andres, Milani, Lili, Ong, Ken K., Perry, John R. B., Porteous, David J., Ritchie, Marylyn D., Smart, Melissa C., Smith, Blair H., Tung, Joyce Y., Wareham, Nicholas J., Wilson, James F., Beauchamp, Jonathan P., Conley, Dalton C., Esko, Tõnu, Lehrer, Steven F., Magnusson, Patrik K. E., Oskarsson, Sven, Pers, Tune H., Robinson, Matthew R., Thom, Kevin, Watson, Chelsea, Chabris, Christopher F., Meyer, Michelle N., Laibson, David I., Yang, Jian, Johannesson, Magnus, Koellinger, Philipp D., Turley, Patrick, Visscher, Peter M., Benjamin, Daniel J., Cesarini, David
Published in Nature genetics (01.08.2018)
Published in Nature genetics (01.08.2018)
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Journal Article
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Karlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M., Meddens, Gerardus A., Muntané, Gerard, Sanchez-Roige, Sandra, Rooij, Frank J. van, Taskesen, Erdogan, Wu, Yang, Zhang, Futao, Auton, Adam, Boardman, Jason D., Clark, David W., Conlin, Andrew, Dolan, Conor C., Fischbacher, Urs, Groenen, Patrick J. F., Harris, Kathleen Mullan, Hasler, Gregor, Hofman, Albert, Ikram, Mohammad A., Jain, Sonia, Karlsson, Robert, Kessler, Ronald C., Kooyman, Maarten, MacKillop, James, Männikkö, Minna, Morcillo-Suarez, Carlos, McQueen, Matthew B., Schmidt, Klaus M., Smart, Melissa C., Sutter, Matthias, Thurik, A. Roy, Uitterlinden, André G., White, Jon, Wit, Harriet de, Yang, Jian, Bertram, Lars, Boomsma, Dorret I., Esko, Tõnu, Fehr, Ernst, Hinds, David A., Johannesson, Magnus, Kumari, Meena, Laibson, David, Magnusson, Patrik K. E., Meyer, Michelle N., Navarro, Arcadi, Palmer, Abraham A., Pers, Tune H., Posthuma, Danielle, Schunk, Daniel, Stein, Murray B., Svento, Rauli, Tiemeier, Henning, Timmers, Paul R. H. J., Turley, Patrick, Ursano, Robert J., Wagner, Gert G., Wilson, James F., Gratten, Jacob, Lee, James J., Cesarini, David, Benjamin, Daniel J., Koellinger, Philipp D., Beauchamp, Jonathan P.
Published in Nature genetics (01.02.2019)
Published in Nature genetics (01.02.2019)
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