Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques
Mercado, Noe B., Zahn, Roland, Wegmann, Frank, Loos, Carolin, Chandrashekar, Abishek, Yu, Jingyou, Liu, Jinyan, Peter, Lauren, McMahan, Katherine, Tostanoski, Lisa H., He, Xuan, Martinez, David R., Rutten, Lucy, Bos, Rinke, van Manen, Danielle, Vellinga, Jort, Custers, Jerome, Langedijk, Johannes P., Kwaks, Ted, Bakkers, Mark J. G., Zuijdgeest, David, Rosendahl Huber, Sietske K., Atyeo, Caroline, Fischinger, Stephanie, Burke, John S., Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Bondzie, Esther A., Dagotto, Gabriel, Gebre, Makda S., Hoffman, Emily, Jacob-Dolan, Catherine, Kirilova, Marinela, Li, Zhenfeng, Lin, Zijin, Mahrokhian, Shant H., Maxfield, Lori F., Nampanya, Felix, Nityanandam, Ramya, Nkolola, Joseph P., Patel, Shivani, Ventura, John D., Verrington, Kaylee, Wan, Huahua, Pessaint, Laurent, Van Ry, Alex, Blade, Kelvin, Strasbaugh, Amanda, Cabus, Mehtap, Brown, Renita, Cook, Anthony, Zouantchangadou, Serge, Teow, Elyse, Andersen, Hanne, Lewis, Mark G., Cai, Yongfei, Chen, Bing, Schmidt, Aaron G., Reeves, R. Keith, Baric, Ralph S., Lauffenburger, Douglas A., Alter, Galit, Stoffels, Paul, Mammen, Mathai, Van Hoof, Johan, Schuitemaker, Hanneke, Barouch, Dan H.
Published in Nature (London) (22.10.2020)
Published in Nature (London) (22.10.2020)
Get full text
Journal Article
Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity
Bakkers, Mark J.G., Lang, Yifei, Feitsma, Louris J., Hulswit, Ruben J.G., de Poot, Stefanie A.H., van Vliet, Arno L.W., Margine, Irina, de Groot-Mijnes, Jolanda D.F., van Kuppeveld, Frank J.M., Langereis, Martijn A., Huizinga, Eric G., de Groot, Raoul J.
Published in Cell Host & Microbe (08.03.2017)
Published in Cell Host & Microbe (08.03.2017)
Get full text
Journal Article
Web Resource
Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A
Hulswit, Ruben J. G., Lang, Yifei, Bakkers, Mark J. G., Li, Wentao, Li, Zeshi, Schouten, Arie, Ophorst, Bram, van Kuppeveld, Frank J. M., Boons, Geert-Jan, Bosch, Berend-Jan, Huizinga, Eric G., de Groot, Raoul J.
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2019)
Get full text
Journal Article
Stabilizing the closed SARS-CoV-2 spike trimer
Juraszek, Jarek, Rutten, Lucy, Blokland, Sven, Bouchier, Pascale, Voorzaat, Richard, Ritschel, Tina, Bakkers, Mark J. G., Renault, Ludovic L. R., Langedijk, Johannes P. M.
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
Get full text
Journal Article
Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses
Bos, Rinke, Rutten, Lucy, van der Lubbe, Joan E. M., Bakkers, Mark J. G., Hardenberg, Gijs, Wegmann, Frank, Zuijdgeest, David, de Wilde, Adriaan H., Koornneef, Annemart, Verwilligen, Annemiek, van Manen, Danielle, Kwaks, Ted, Vogels, Ronald, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Li, Zhenfeng, Barouch, Dan H., Vellinga, Jort, Langedijk, Johannes P. M., Zahn, Roland C., Custers, Jerome, Schuitemaker, Hanneke
Published in npj vaccines (28.09.2020)
Published in npj vaccines (28.09.2020)
Get full text
Journal Article
CD164 is a host factor for lymphocytic choriomeningitis virus entry
Bakkers, Mark J G, Moon-Walker, Alex, Herlo, Rasmus, Brusic, Vesna, Stubbs, Sarah Hulsey, Hastie, Kathryn M, Saphire, Erica Ollmann, Kirchhausen, Tomas L, Whelan, Sean P J
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2022)
Get full text
Journal Article
9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate
Baumann, Anna-Maria T., Bakkers, Mark J. G., Buettner, Falk F. R., Hartmann, Maike, Grove, Melanie, Langereis, Martijn A., de Groot, Raoul J., Mühlenhoff, Martina
Published in Nature communications (14.07.2015)
Published in Nature communications (14.07.2015)
Get full text
Journal Article
Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions
Milder, Fin J, Jongeneelen, Mandy, Ritschel, Tina, Bouchier, Pascale, Bisschop, Ilona J M, de Man, Martijn, Veldman, Daniel, Le, Lam, Kaufmann, Baerbel, Bakkers, Mark J G, Juraszek, Jarek, Brandenburg, Boerries, Langedijk, Johannes P M
Published in Proceedings of the National Academy of Sciences - PNAS (08.02.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (08.02.2022)
Get full text
Journal Article
Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike
Yu, Xiaodi, Juraszek, Jarek, Rutten, Lucy, Bakkers, Mark J G, Blokland, Sven, Melchers, Jelle M, van den Broek, Niels J F, Verwilligen, Annemiek Y W, Abeywickrema, Pravien, Vingerhoets, Johan, Neefs, Jean-Marc, Bakhash, Shah A Mohamed, Roychoudhury, Pavitra, Greninger, Alex, Sharma, Sujata, Langedijk, Johannes P M
Published in PLoS pathogens (01.05.2023)
Published in PLoS pathogens (01.05.2023)
Get full text
Journal Article
Coronavirus receptor switch explained from the stereochemistry of protein–carbohydrate interactions and a single mutation
Bakkers, Mark J. G., Zeng, Qinghong, Feitsma, Louris J., Hulswit, Ruben J. G., Li, Zeshi, Westerbeke, Aniek, van Kuppeveld, Frank J. M., Boons, Geert-Jan, Langereis, Martijn A., Huizinga, Eric G., de Groot, Raoul J.
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2016)
Get full text
Journal Article
GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay
Rumping, Lynne, Tessadori, Federico, Pouwels, Petra J W, Vringer, Esmee, Wijnen, Jannie P, Bhogal, Alex A, Savelberg, Sanne M C, Duran, Karen J, Bakkers, Mark J G, Ramos, Rúben J J, Schellekens, Peter A W, Kroes, Hester Y, Klomp, Dennis W J, Black, Graeme C M, Taylor, Rachel L, Bakkers, Jeroen P W, Prinsen, Hubertus C M T, van der Knaap, Marjo S, Dansen, Tobias B, Rehmann, Holger, Zwartkruis, Fried J T, Houwen, Roderick H J, van Haaften, Gijs, Verhoeven-Duif, Nanda M, Jans, Judith J M, van Hasselt, Peter M
Published in Human molecular genetics (01.01.2019)
Published in Human molecular genetics (01.01.2019)
Get full text
Journal Article
Reconstruction of the cell entry pathway of an extinct virus
Robinson-McCarthy, Lindsey R, McCarthy, Kevin R, Raaben, Matthijs, Piccinotti, Silvia, Nieuwenhuis, Joppe, Stubbs, Sarah H, Bakkers, Mark J G, Whelan, Sean P J
Published in PLoS pathogens (01.08.2018)
Published in PLoS pathogens (01.08.2018)
Get full text
Journal Article
Design and Preclinical Evaluation of a Nanoparticle Vaccine against Respiratory Syncytial Virus Based on the Attachment Protein G
Voorzaat, Richard, Cox, Freek, van Overveld, Daan, Le, Lam, Tettero, Lisanne, Vaneman, Joost, Bakkers, Mark J G, Langedijk, Johannes P M
Published in Vaccines (Basel) (01.03.2024)
Published in Vaccines (Basel) (01.03.2024)
Get full text
Journal Article
Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins
Langereis, Martijn A., Bakkers, Mark J.G., Deng, Lingquan, Padler-Karavani, Vered, Vervoort, Stephin J., Hulswit, Ruben J.G., van Vliet, Arno L.W., Gerwig, Gerrit J., de Poot, Stefanie A.H., Boot, Willemijn, van Ederen, Anne Marie, Heesters, Balthasar A., van der Loos, Chris M., van Kuppeveld, Frank J.M., Yu, Hai, Huizinga, Eric G., Chen, Xi, Varki, Ajit, Kamerling, Johannis P., de Groot, Raoul J.
Published in Cell reports (Cambridge) (30.06.2015)
Published in Cell reports (Cambridge) (30.06.2015)
Get full text
Journal Article