Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron
Lindström, Nils O, Lawrence, Melanie L, Burn, Sally F, Johansson, Jeanette A, Bakker, Elvira R M, Ridgway, Rachel A, Chang, C-Hong, Karolak, Michele J, Oxburgh, Leif, Headon, Denis J, Sansom, Owen J, Smits, Ron, Davies, Jamie A, Hohenstein, Peter
Published in eLife (03.02.2015)
Published in eLife (03.02.2015)
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R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach
Sigal, Michael, Reinés, Maria del Mar, Müllerke, Stefanie, Fischer, Cornelius, Kapalczynska, Marta, Berger, Hilmar, Bakker, Elvira R. M., Mollenkopf, Hans-Joachim, Rothenberg, Michael E., Wiedenmann, Bertram, Sauer, Sascha, Meyer, Thomas F.
Published in Nature cell biology (01.07.2019)
Published in Nature cell biology (01.07.2019)
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β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis
van Veelen, Wendy, Le, Ngoc H, Helvensteijn, Werner, Blonden, Lau, Theeuwes, Myrte, Bakker, Elvira R M, Franken, Patrick F, van Gurp, Léon, Meijlink, Frits, van der Valk, Martin A, Kuipers, Ernst J, Fodde, Riccardo, Smits, Ron
Published in Gut (01.09.2011)
Published in Gut (01.09.2011)
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Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer
Rätze, Max A. K., Koorman, Thijs, Sijnesael, Thijmen, Bassey-Archibong, Blessing, van de Ven, Robert, Enserink, Lotte, Visser, Daan, Jaksani, Sridevi, Viciano, Ignacio, Bakker, Elvira R. M., Richard, François, Tutt, Andrew, O’Leary, Lynda, Fitzpatrick, Amanda, Roca-Cusachs, Pere, van Diest, Paul J., Desmedt, Christine, Daniel, Juliet M., Isacke, Clare M., Derksen, Patrick W. B.
Published in Oncogene (20.05.2022)
Published in Oncogene (20.05.2022)
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Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation
Koopmans, Tim, Hesse, Laura, Nawijn, Martijn C., Kumawat, Kuldeep, Menzen, Mark H., Sophie T. Bos, I., Smits, Ron, Bakker, Elvira R. M., van den Berge, Maarten, Koppelman, Gerard H., Guryev, Victor, Gosens, Reinoud
Published in Scientific reports (21.04.2020)
Published in Scientific reports (21.04.2020)
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Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer
Rätze, Max A. K., Koorman, Thijs, Sijnesael, Thijmen, Bassey-Archibong, Blessing, van de Ven, Robert, Enserink, Lotte, Visser, Daan, Jaksani, Sridevi, Viciano, Ignacio, Bakker, Elvira R. M., Richard, François, Tutt, Andrew, O’Leary, Lynda, Fitzpatrick, Amanda, Roca-Cusachs, Pere, van Diest, Paul J., Desmedt, Christine, Daniel, Juliet M., Isacke, Clare M., Derksen, Patrick W. B.
Published in Oncogene (01.06.2022)
Published in Oncogene (01.06.2022)
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Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice
Lyraki, Rodanthi, Grabek, Anaëlle, Tison, Amélie, Weerasinghe Arachchige, Lahiru Chamara, Peitzsch, Mirko, Bechmann, Nicole, Youssef, Sameh A, de Bruin, Alain, Bakker, Elvira R M, Claessens, Frank, Chaboissier, Marie-Christine, Schedl, Andreas
Published in Disease models & mechanisms (01.06.2023)
Published in Disease models & mechanisms (01.06.2023)
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SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype
Raghoebir, Lalini, Bakker, Elvira R M, Mills, Jason C, Swagemakers, Sigrid, Kempen, Marjon Buscop-van, Munck, Anne Boerema-de, Driegen, Siska, Meijer, Dies, Grosveld, Frank, Tibboel, Dick, Smits, Ron, Rottier, Robbert J
Published in Journal of molecular cell biology (01.12.2012)
Published in Journal of molecular cell biology (01.12.2012)
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Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance
Ikink, Gerjon J., Boer, Mandy, Bakker, Elvira R. M., Vendel-Zwaagstra, Annabel, Klijn, Chris, ten Hoeve, Jelle, Jonkers, Jos, Wessels, Lodewyk F., Hilkens, John
Published in Oncogene (01.03.2018)
Published in Oncogene (01.03.2018)
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R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling
ter Steege, Eline J., Doornbos, Loes W., Haughton, Peter D., van Diest, Paul J., Hilkens, John, Derksen, Patrick W.B., Bakker, Elvira R.M.
Published in Cancer letters (01.08.2023)
Published in Cancer letters (01.08.2023)
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LGR6-dependent conditional inactivation of E-cadherin and p53 leads to invasive skin and mammary carcinomas in mice
ter Steege, Eline J., Sijnesael, Thijmen, Enserink, Lotte, Klarenbeek, Sjoerd, Haakma, Wisse E., Bakker, Elvira R.M., Derksen, Patrick W.B.
Published in Neoplasia (New York, N.Y.) (01.01.2023)
Published in Neoplasia (New York, N.Y.) (01.01.2023)
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Wnt5a promotes human colon cancer cell migration and invasion but does not augment intestinal tumorigenesis in Apc1638N mice
Bakker, Elvira R M, Das, Asha Mooppilmadham, Helvensteijn, Werner, Franken, Patrick F, Swagemakers, Sigrid, van der Valk, Martin A, ten Hagen, Timo L M, Kuipers, Ernst J, van Veelen, Wendy, Smits, Ron
Published in Carcinogenesis (New York) (01.11.2013)
Published in Carcinogenesis (New York) (01.11.2013)
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Colorectal cancers choosing sides
Albuquerque, Cristina, Bakker, Elvira R.M., van Veelen, Wendy, Smits, Ron
Published in Biochimica et biophysica acta (01.12.2011)
Published in Biochimica et biophysica acta (01.12.2011)
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R‐spondin‐3 is an oncogenic driver of poorly differentiated invasive breast cancer
Steege, Eline J, Boer, Mandy, Timmer, Nikki C, Ammerlaan, Carola ME, Song, Ji‐Ying, Derksen, Patrick WB, Hilkens, John, Bakker, Elvira RM
Published in The Journal of pathology (01.11.2022)
Published in The Journal of pathology (01.11.2022)
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RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis
Hilkens, John, Timmer, Nikki C, Boer, Mandy, Ikink, Gerjon J, Schewe, Matthias, Sacchetti, Andrea, Koppens, Martijn A J, Song, Ji-Ying, Bakker, Elvira R M
Published in Gut (01.06.2017)
Published in Gut (01.06.2017)
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Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity
Verhaar, Auke P., Hoekstra, Elmer, Tjon, Angela S. W., Utomo, Wesley K., Deuring, J. Jasper, Bakker, Elvira R. M., Muncan, Vanesa, Peppelenbosch, Maikel P.
Published in Scientific reports (27.06.2014)
Published in Scientific reports (27.06.2014)
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Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice
Bakker, Elvira R.M., Raghoebir, Lalini, Franken, Patrick F., Helvensteijn, Werner, van Gurp, Léon, Meijlink, Frits, van der Valk, Martin A., Rottier, Robbert J., Kuipers, Ernst J., van Veelen, Wendy, Smits, Ron
Published in Developmental biology (01.09.2012)
Published in Developmental biology (01.09.2012)
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