An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides
Baker, Ysobel R., Thorpe, Cameron, Chen, Jinfeng, Poller, Laura M., Cox, Lina, Kumar, Pawan, Lim, Wooi F., Lie, Lillian, McClorey, Graham, Epple, Sven, Singleton, Daniel, McDonough, Michael A., Hardwick, Jack S., Christensen, Kirsten E., Wood, Matthew J. A., Hall, James P., El-Sagheer, Afaf H., Brown, Tom
Published in Nature communications (12.07.2022)
Published in Nature communications (12.07.2022)
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Journal Article
Design and synthesis of a biotinylated chemical probe for detecting the molecular targets of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin
Baker, Ysobel R, Galloway, Warren R J D, Hodgkinson, James T, Spring, David R
Published in Molecules (Basel, Switzerland) (25.09.2013)
Published in Molecules (Basel, Switzerland) (25.09.2013)
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Preparation and characterization of manganese, cobalt and zinc DNA nanoflowers with tuneable morphology, DNA content and size
Baker, Ysobel R, Chen, Jinfeng, Brown, Jason, El-Sagheer, Afaf H, Wiseman, Philip, Johnson, Errin, Goddard, Paul, Brown, Tom
Published in Nucleic acids research (06.09.2018)
Published in Nucleic acids research (06.09.2018)
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Journal Article
Enzyme-free synthesis of cyclic single-stranded DNA constructs containing a single triazole, amide or phosphoramidate backbone linkage and their use as templates for rolling circle amplification and nanoflower formation
Chen, Jinfeng, Baker, Ysobel R, Brown, Asha, El-Sagheer, Afaf H, Brown, Tom
Published in Chemical science (Cambridge) (14.11.2018)
Published in Chemical science (Cambridge) (14.11.2018)
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Journal Article
A new Pseudomonas quinolone signal (PQS) binding partner: MexG
Hodgkinson, James T., Gross, Jeremy, Baker, Ysobel R., Spring, David R., Welch, M.
Published in Chemical science (Cambridge) (21.04.2016)
Published in Chemical science (Cambridge) (21.04.2016)
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Journal Article
A New 1,5-Disubstituted Triazole DNA Backbone Mimic with Enhanced Polymerase Compatibility
Epple, Sven, Modi, Aman, Baker, Ysobel R, Wȩgrzyn, Ewa, Traoré, Diallo, Wanat, Przemyslaw, Tyburn, Agnes E. S, Shivalingam, Arun, Taemaitree, Lapatrada, El-Sagheer, Afaf H, Brown, Tom
Published in Journal of the American Chemical Society (06.10.2021)
Published in Journal of the American Chemical Society (06.10.2021)
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Journal Article
Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling
Wu, Yuteng, Olsen, Lasse B., Lau, Yu Heng, Jensen, Claus Hatt, Rossmann, Maxim, Baker, Ysobel R., Sore, Hannah F., Collins, Súil, Spring, David R.
Published in Chembiochem : a European journal of chemical biology (15.04.2016)
Published in Chembiochem : a European journal of chemical biology (15.04.2016)
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Journal Article
Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides
Dysko, Anna, Baker, Ysobel R, McClorey, Graham, Wood, Matthew J. A, Fenner, Sabine, Williams, Glynn, El-Sagheer, Afaf, Brown, Tom
Published in RSC chemical biology (08.06.2022)
Published in RSC chemical biology (08.06.2022)
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Searching for the ideal triazole: Investigating the 1,5-triazole as a charge neutral DNA backbone mimic
Baker, Ysobel R., Traoré, Diallo, Wanat, Przemyslaw, Tyburn, Agnès, El-Sagheer, Afaf H., Brown, Tom
Published in Tetrahedron (14.02.2020)
Published in Tetrahedron (14.02.2020)
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Enzyme-free synthesis of cyclic single-stranded DNA constructs containing a single triazole, amide or phosphoramidate backbone linkage and their use as templates for rolling circle amplification and nanoflower formationElectronic supplementary information (ESI) available: Experimental protocols, mass spectra, and additional gel electrophoresis results and SEM images. See DOI: 10.1039/c8sc02952k
Chen, Jinfeng, Baker, Ysobel R, Brown, Asha, El-Sagheer, Afaf H, Brown, Tom
Year of Publication 31.10.2018
Year of Publication 31.10.2018
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Journal Article
Enzyme-free synthesis of cyclic single-stranded DNA constructs containing a single triazole, amide or phosphoramidate backbone linkage and their use as templates for rolling circle amplification and nanoflower formation† †Electronic supplementary information (ESI) available: Experimental protocols, mass spectra, and additional gel electrophoresis results and SEM images. See DOI: 10.1039/c8sc02952k
Chen, Jinfeng, Baker, Ysobel R., Brown, Asha, El-Sagheer, Afaf H., Brown, Tom
Published in Chemical science (Cambridge) (24.08.2018)
Published in Chemical science (Cambridge) (24.08.2018)
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Journal Article
A new Pseudomonas quinolone signal (PQS) binding partner: MexGElectronic supplementary information (ESI) available: Full experimental protocols and characterisation data. See DOI: 10.1039/c5sc04197j
Hodgkinson, James T, Gross, Jeremy, Baker, Ysobel R, Spring, David R, Welch, M
Year of Publication 21.03.2016
Year of Publication 21.03.2016
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Journal Article
A new Pseudomonas quinolone signal (PQS) binding partner: MexG† †Electronic supplementary information (ESI) available: Full experimental protocols and characterisation data. See DOI: 10.1039/c5sc04197j
Hodgkinson, James T., Gross, Jeremy, Baker, Ysobel R., Spring, David R., Welch, M.
Published in Chemical science (Cambridge) (20.01.2016)
Published in Chemical science (Cambridge) (20.01.2016)
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