In Vivo HIF-Mediated Reductive Carboxylation Is Regulated by Citrate Levels and Sensitizes VHL-Deficient Cells to Glutamine Deprivation
Gameiro, Paulo A., Yang, Juanjuan, Metelo, Ana M., Pérez-Carro, Rocio, Baker, Rania, Wang, Zongwei, Arreola, Alexandra, Rathmell, W. Kimryn, Olumi, Aria, López-Larrubia, Pilar, Stephanopoulos, Gregory, Iliopoulos, Othon
Published in Cell metabolism (05.03.2013)
Published in Cell metabolism (05.03.2013)
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Journal Article
Protective effect of quercetin compared to silymarin against phenylhydrazine induced anemia
El-Sayed Baker, Rania, Gad, Fatma, fararh, khalid
Published in Benha Veterinary Medical Journal (01.03.2021)
Published in Benha Veterinary Medical Journal (01.03.2021)
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Journal Article
COMPARISON BETWEEN FLOW CYTOMETERIC METHOD AND OTHER METHODS FORRETICULOCYTE COUNT IN DIAGNOSIS OF PHENYLHYDRAZINE-INDUCED HEMOLYTIC ANEMIA
Mohammed Baker, Rania, Abdel-Monem Gad, Fatma, Mostafa Fararh, Khalid
Published in International journal of advanced research (Indore) (28.02.2021)
Published in International journal of advanced research (Indore) (28.02.2021)
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Journal Article
Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model
Metelo, Ana Martins, Noonan, Haley R, Li, Xiang, Jin, Youngnam, Baker, Rania, Kamentsky, Lee, Zhang, Yiyun, van Rooijen, Ellen, Shin, Jordan, Carpenter, Anne E, Yeh, Jing-Ruey, Peterson, Randall T, Iliopoulos, Othon
Published in The Journal of clinical investigation (01.05.2015)
Published in The Journal of clinical investigation (01.05.2015)
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Journal Article
Abstract 1578: Small molecule HIF-2a inhibitors down regulate its activity in vivo and ameliorate the vhl zebrafish phenotype
Metelo, Ana, Xiang, Li, Baker, Rania, Kamentsky, Lee, Carpenter, Anne, Peterson, Randall
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
PI-09 PRECLINICAL TESTING OF SMALL MOLECULE HIF2α INHIBITOR IN ZEBRAFISH AND MOUSE MODELS OF VHL-DEFICIENT RENAL CELL CARCINOMA
Schneider, Meike, Metelo, Ana, Noonan, Haley, Li, Xiang, Youngnam, Jing, Olson, Nick, Baker, Rania, Kamentsky, Lee, Zhang, Yiyun, Carpenter, Anne, Yeh, Jing-Ruey, Peterson, Randall, Iliopoulos, Othon
Published in The Journal of urology (01.04.2015)
Published in The Journal of urology (01.04.2015)
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Journal Article
Abstract 4253: In vivo activity of small molecule HIF2α inhibitors
Metelo, Ana Marguerita, Xiang, Li, Baker, Rania, Burger, Alexa, Peterson, Randall, Iliopoulos, Othon
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Pharmacological HIF2[alpha] inhibition improves VHL disease-associated phenotypes in zebrafish model
Metelo, Ana Martins, Noonan, Haley R, Xiang, Li, Jin, Youngnam, Baker, Rania, Kamentsky, Lee, Zhang, Yiyun, van Rooijen, Ellen, Shin, Jordan, Carpenter, Anne E, Yeh, Jing-Ruey, Peterson, Randall T, Iliopoulos, Othon
Published in The Journal of clinical investigation (01.05.2015)
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Published in The Journal of clinical investigation (01.05.2015)
Journal Article
Abstract 1881: Hypoxia Inducible Factor (HIF) promotes reductive carboxylation by regulating citrate levels and renders VHL-deficient and hypoxic cells sensitive to glutamine deprivation
Gameiro, Paulo, Metelo, Ana, Pérez-Carro, Rocio, Arreolla, Alexandra, Baker, Rania, Wang, Zongwei, Olumi, Aria, Rathmell, Kimryn, López-Larrubia, Pilar, Stephanopoulos, Gregory, Iliopoulos, Othon
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article