FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
Cooke, Mariana, Kreider-Letterman, Gabriel, Baker, Martin J., Zhang, Suli, Sullivan, Neil T., Eruslanov, Evgeniy, Abba, Martin C., Goicoechea, Silvia M., García-Mata, Rafael, Kazanietz, Marcelo G.
Published in Cell reports (Cambridge) (02.11.2021)
Published in Cell reports (Cambridge) (02.11.2021)
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Journal Article
Evaluation of active Rac1 levels in cancer cells: A case of misleading conclusions from immunofluorescence analysis
Baker, Martin J., Cooke, Mariana, Kreider-Letterman, Gabriel, Garcia-Mata, Rafael, Janmey, Paul A., Kazanietz, Marcelo G.
Published in The Journal of biological chemistry (02.10.2020)
Published in The Journal of biological chemistry (02.10.2020)
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Journal Article
The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues
Johnsson, Anna-Karin E, Dai, Yanfeng, Nobis, Max, Baker, Martin J, McGhee, Ewan J, Walker, Simon, Schwarz, Juliane P, Kadir, Shereen, Morton, Jennifer P, Myant, Kevin B, Huels, David J, Segonds-Pichon, Anne, Sansom, Owen J, Anderson, Kurt I, Timpson, Paul, Welch, Heidi C E
Published in Cell reports (Cambridge) (01.03.2014)
Published in Cell reports (Cambridge) (01.03.2014)
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Rac-GEF/Rac Signaling and Metastatic Dissemination in Lung Cancer
Cooke, Mariana, Baker, Martin J, Kazanietz, Marcelo G
Published in Frontiers in cell and developmental biology (25.02.2020)
Published in Frontiers in cell and developmental biology (25.02.2020)
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Journal Article
Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1
Pan, Dingxin, Barber, Mark A., Hornigold, Kirsti, Baker, Martin J., Toth, Judit M., Oxley, David, Welch, Heidi C.E.
Published in The Journal of biological chemistry (18.03.2016)
Published in The Journal of biological chemistry (18.03.2016)
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Journal Article
P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer
Baker, Martin J, Abba, Martín C, Garcia-Mata, Rafael, Kazanietz, Marcelo G
Published in Cancers (19.02.2020)
Published in Cancers (19.02.2020)
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Journal Article
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses
Hornigold, Kirsti, Baker, Martin J, Machin, Polly A, Chetwynd, Stephen A, Johnsson, Anna-Karin, Pantarelli, Chiara, Islam, Priota, Stammers, Melanie, Crossland, Laraine, Oxley, David, Okkenhaug, Hanneke, Walker, Simon, Walker, Rachael, Segonds-Pichon, Anne, Fukui, Yoshinori, Malliri, Angeliki, Welch, Heidi C E
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
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P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells
Hampson, Elizabeth, Tsonou, Elpida, Baker, Martin J., Hornigold, David C., Hubbard, Roderick E., Massey, Andrew, Welch, Heidi C. E.
Published in Cells (Basel, Switzerland) (18.09.2021)
Published in Cells (Basel, Switzerland) (18.09.2021)
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Journal Article
The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic
Casado-Medrano, Victoria, Baker, Martin J, Lopez-Haber, Cynthia, Cooke, Mariana, Wang, Shaofei, Caloca, Maria J, Kazanietz, Marcelo G
Published in Biochemical Society transactions (20.08.2018)
Published in Biochemical Society transactions (20.08.2018)
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Journal Article
The PKC universe keeps expanding: From cancer initiation to metastasis
Rahimova, Nilufar, Cooke, Mariana, Zhang, Suli, Baker, Martin J., Kazanietz, Marcelo G.
Published in Advances in biological regulation (01.12.2020)
Published in Advances in biological regulation (01.12.2020)
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Journal Article
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells
Ginn, Lucy, Maltas, Joe, Baker, Martin J, Chaturvedi, Anshuman, Wilson, Leah, Guilbert, Ryan, Amaral, Fabio M R, Priest, Lynsey, Mole, Holly, Blackhall, Fiona, Diamantopoulou, Zoi, Somervaille, Tim C P, Hurlstone, Adam, Malliri, Angeliki
Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2023)
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Journal Article
Activating RAC1 variants in the switch II region cause a developmental syndrome and alter neuronal morphology
Banka, Siddharth, Bennington, Abigail, Baker, Martin J, Rijckmans, Ellen, Clemente, Giuliana D, Ansor, Nurhuda Mohamad, Sito, Hilary, Prasad, Pritha, Anyane-Yeboa, Kwame, Badalato, Lauren, Dimitrov, Boyan, Fitzpatrick, David, Hurst, Anna C E, Jansen, Anna C, Kelly, Melissa A, Krantz, Ian, Rieubland, Claudine, Ross, Meredith, Rudy, Natasha L, Sanz, Javier, Stouffs, Katrien, Xu, Zhuo Luan, Malliri, Angeliki, Kazanietz, Marcelo G, Millard, Tom H
Published in Brain (London, England : 1878) (19.12.2022)
Published in Brain (London, England : 1878) (19.12.2022)
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Journal Article
Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes
Cooke, Mariana, Zhou, Xiaoling, Casado-Medrano, Victoria, Lopez-Haber, Cynthia, Baker, Martin J., Garg, Rachana, Ann, Jihyae, Lee, Jeewoo, Blumberg, Peter M., Kazanietz, Marcelo G.
Published in The Journal of biological chemistry (01.06.2018)
Published in The Journal of biological chemistry (01.06.2018)
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Journal Article
Mechanical strain stimulates COPII‐dependent secretory trafficking via Rac1
Phuyal, Santosh, Djaerff, Elena, Le Roux, Anabel‐Lise, Baker, Martin J, Fankhauser, Daniela, Mahdizadeh, Sayyed Jalil, Reiterer, Veronika, Parizadeh, Amirabbas, Felder, Edward, Kahlhofer, Jennifer C, Teis, David, Kazanietz, Marcelo G, Geley, Stephan, Eriksson, Leif, Roca‐Cusachs, Pere, Farhan, Hesso
Published in The EMBO journal (15.09.2022)
Published in The EMBO journal (15.09.2022)
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Journal Article
PKCε regulates Rho GTPases and actin cytoskeleton reorganization in non-small cell lung cancer cells
Cooke, Mariana, Baker, Martin J, Kazanietz, Marcelo G, Casado-Medrano, Victoria
Published in Small GTPases (01.05.2021)
Published in Small GTPases (01.05.2021)
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Journal Article
Germline intergenic duplications at Xq26.1 underlie Bazex–Dupré–Christol basal cell carcinoma susceptibility syndrome
Liu, Yanshan, Banka, Siddharth, Huang, Yingzhi, Hardman‐Smart, Jonathan, Pye, Derek, Torrelo, Antonio, Beaman, Glenda M., Kazanietz, Marcelo G., Baker, Martin J., Ferrazzano, Carlo, Shi, Chenfu, Orozco, Gisela, Eyre, Stephen, Geel, Michel, Bygum, Anette, Fischer, Judith, Miedzybrodzka, Zosia, Abuzahra, Faris, Rübben, Albert, Cuvertino, Sara, Ellingford, Jamie M., Smith, Miriam J., Evans, D. Gareth, Weppner‐Parren, Lizelotte J.M.T., Steensel, Maurice A.M., Chaudhary, Iskander H., Mangham, D. Chas, Lear, John T., Paus, Ralf, Frank, Jorge, Newman, William G., Zhang, Xue
Published in British journal of dermatology (1951) (01.12.2022)
Published in British journal of dermatology (1951) (01.12.2022)
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