OCT Risk Factors for Development of Late Age-Related Macular Degeneration in the Fellow Eyes of Patients Enrolled in the HARBOR Study
Nassisi, Marco, Lei, Jianqin, Abdelfattah, Nizar Saleh, Karamat, Ayesha, Balasubramanian, Siva, Fan, Wenying, Uji, Akihito, Marion, Kenneth M., Baker, Kirstie, Huang, Xiwen, Morgenthien, Elizabeth, Sadda, Srinivas R.
Published in Ophthalmology (Rochester, Minn.) (01.12.2019)
Published in Ophthalmology (Rochester, Minn.) (01.12.2019)
Get full text
Journal Article
Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration
Ambati, Meenakshi, Apicella, Ivana, Wang, Shao-bin, Narendran, Siddharth, Leung, Hannah, Pereira, Felipe, Nagasaka, Yosuke, Huang, Peirong, Varshney, Akhil, Baker, Kirstie L., Marion, Kenneth M., Shadmehr, Mehrdad, Stains, Cliff I., Werner, Brian C., Sadda, Srinivas R., Taylor, Ethan W., Sutton, S. Scott, Magagnoli, Joseph, Gelfand, Bradley D.
Published in Proceedings of the National Academy of Sciences - PNAS (12.10.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (12.10.2021)
Get full text
Journal Article
A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration
Narendran, Siddharth, Pereira, Felipe, Yerramothu, Praveen, Apicella, Ivana, Wang, Shao-Bin, Varshney, Akhil, Baker, Kirstie L, Marion, Kenneth M, Ambati, Meenakshi, Ambati, Vidya L, Ambati, Kameshwari, Sadda, Srinivas R, Gelfand, Bradley D, Ambati, Jayakrishna
Published in Investigative ophthalmology & visual science (04.08.2020)
Published in Investigative ophthalmology & visual science (04.08.2020)
Get full text
Journal Article
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs
Wang, Shao-Bin, Narendran, Siddharth, Hirahara, Shuichiro, Varshney, Akhil, Pereira, Felipe, Apicella, Ivana, Ambati, Meenakshi, Ambati, Vidya L, Yerramothu, Praveen, Ambati, Kameshwari, Nagasaka, Yosuke, Argyle, Dionne, Huang, Peirong, Baker, Kirstie L, Marion, Kenneth M, Gupta, Kartik, Liu, Bo, Hinton, David R, Canna, Scott W, Sallam, Tamer, Sadda, Srinivas R, Kerur, Nagaraj, Gelfand, Bradley D, Ambati, Jayakrishna
Published in Science immunology (03.12.2021)
Published in Science immunology (03.12.2021)
Get more information
Journal Article
Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration
Narendran, Siddharth, Pereira, Felipe, Yerramothu, Praveen, Apicella, Ivana, Wang, Shao-bin, Ambati, Kameshwari, Hirahara, Shuichiro, Kim, Younghee, Ambati, Meenakshi, Ambati, Vidya L., Huang, Peirong, Varshney, Akhil, Nagasaka, Yosuke, Fukuda, Shinichi, Baker, Kirstie L., Marion, Kenneth M., Deussing, Jan M., Sadda, Srinivas R., Gelfand, Bradley D., Ambati, Jayakrishna
Published in Signal transduction and targeted therapy (14.04.2021)
Published in Signal transduction and targeted therapy (14.04.2021)
Get full text
Journal Article
Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity
Fukuda, Shinichi, Narendran, Siddharth, Varshney, Akhil, Nagasaka, Yosuke, Wang, Shao-Bin, Ambati, Kameshwari, Apicella, Ivana, Pereira, Felipe, Fowler, Benjamin J, Yasuma, Tetsuhiro, Hirahara, Shuichiro, Yasuma, Reo, Huang, Peirong, Yerramothu, Praveen, Makin, Ryan D, Wang, Mo, Baker, Kirstie L, Marion, Kenneth M, Huang, Xiwen, Baghdasaryan, Elmira, Ambati, Meenakshi, Ambati, Vidya L, Banerjee, Daipayan, Bonilha, Vera L, Tolstonog, Genrich V, Held, Ulrike, Ogura, Yuichiro, Terasaki, Hiroko, Oshika, Tetsuro, Bhattarai, Deepak, Kim, Kyung Bo, Feldman, Sanford H, Aguirre, J Ignacio, Hinton, David R, Kerur, Nagaraj, Sadda, Srinivas R, Schumann, Gerald G, Gelfand, Bradley D, Ambati, Jayakrishna
Published in Science advances (01.10.2021)
Published in Science advances (01.10.2021)
Get full text
Journal Article
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration
Fukuda, Shinichi, Varshney, Akhil, Fowler, Benjamin J., Wang, Shao-bin, Narendran, Siddharth, Ambati, Kameshwari, Yasuma, Tetsuhiro, Magagnoli, Joseph, Leung, Hannah, Hirahara, Shuichiro, Nagasaka, Yosuke, Yasuma, Reo, Apicella, Ivana, Pereira, Felipe, Makin, Ryan D., Magner, Eamonn, Liu, Xinan, Sun, Jian, Wang, Mo, Baker, Kirstie, Marion, Kenneth M., Huang, Xiwen, Baghdasaryan, Elmira, Ambati, Meenakshi, Ambati, Vidya L., Pandey, Akshat, Pandya, Lekha, Cummings, Tammy, Banerjee, Daipayan, Huang, Peirong, Yerramothu, Praveen, Tolstonog, Genrich V., Held, Ulrike, Erwin, Jennifer A., Paquola, Apua C. M., Herdy, Joseph R., Ogura, Yuichiro, Terasaki, Hiroko, Oshika, Tetsuro, Darwish, Shaban, Singh, Ramendra K., Mozaffari, Saghar, Bhattarai, Deepak, Kim, Kyung Bo, Hardin, James W., Bennett, Charles L., Hinton, David R., Hanson, Timothy E., Röver, Christian, Parang, Keykavous, Kerur, Nagaraj, Liu, Jinze, Werner, Brian C., Sutton, S.Scott, Sadda, Srinivas R., Schumann, Gerald G., Gelfand, Bradley D., Gage, Fred H., Ambati, Jayakrishna
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2021)
Get full text
Journal Article
Detailed genetic characteristics of an international large cohort of patients with Stargardt disease: ProgStar study report 8
Fujinami, Kaoru, Audo, Isabelle S, Birch, David G, Bomotti, Samantha M, Marino, Meghan J, Sahel, José-Alain, Sunness, Janet S, Wojciechowski, Robert, Zrenner, Eberhart, Michaelides, Michel, Scholl, Hendrik PN, Strauss, Rupert W, Wolfson, Yulia, Shah, Syed Mahmood, Ahmed, Mohamed, Fujinami, Kaoru, Traboulsi, Elias, Marino, Meghan, Crowe, Susan, Fecko, Tami, Applegate, Carol, Esposti, Simona Degli, Webster, Andrew, Connor, Sophie, Barnfield, Jade, Alfageme, Clara, Pefkianaki, Maria, Aboshiha, Jonathan, Liew, Gerald, Holder, Graham, Cajas Narvaez, Daniela Ivanova, Grigg, Catherine, Rughani, Avani, Amoah, Charles, Bibi, Kanom, Begum, Hamida, Carter, Andrew, Shinmar, Harpreet, Bernstein, Paul, Wegner, Kimberley, Carlstrom, Bonnie, Farnsworth, Kellian, Fry, Cyrie, Chandler, Melissa, Birch, David, Wang, Yi-Zhong, Rodriguez, Luis, Klein, Martin, Mejia, Paulina, Cideciyan, Artur V, Matsui, Rodrigo, Gruzensky, Michaela, Hahn, Gesa Astrid, Wilhelm, Barbara, Peters, Tobias, Koenig, Tilman, Kramer, Susanne, Mohand-Said, Saddek, Zeitz, Christina, Boyard, Fiona, Tran, Minh Ha, Chapon, Mathias, Emmert, David G, Herring, Mark, Bassinger, Jennifer, West, Sheila K, Ip, Michael S, Ho, Alex, Uji, Akihito, Hariri, Amirhossein, Elshafei, Anthony, Jenkins, Dennis, Baghdasaryan, Elmira, Samson, Feliz, Akil, Handan, Lei, Jianqin, Falavarjani, Khalil G, Espino, Kristina, Roded, Netali, Saleh, Nizar, Huang, Ping, Margaryan, Teresa, Murillo, Yamileth, Santos, Lisa, Perez, Silvia, Chao, Stephanie, Luna, Zoila, Menchaca, Anita, Robledo, Vicky, Baker, Kirstie, Bluemel, Daniel, Nava, Lorane, Oberoi, Michelle, Romero, Mark, Chiguil, Vivian, Bynum-Bain, Grantley, Mendiguren, Carolina, Huang, Xiwen, Eberhart, Zrenner, Hahn, Gesa
Published in British journal of ophthalmology (01.03.2019)
Published in British journal of ophthalmology (01.03.2019)
Get full text
Journal Article
Visual Acuity Loss and Associated Risk Factors in the Retrospective Progression of Stargardt Disease Study (ProgStar Report No. 2)
Kong, Xiangrong, PhD, Strauss, Rupert W., MD, Michaelides, Michel, MD, Cideciyan, Artur V., PhD, Sahel, José-Alain, MD, Muñoz, Beatriz, MS, West, Sheila, PhD, Scholl, Hendrik P.N., MD, MA
Published in Ophthalmology (Rochester, Minn.) (01.09.2016)
Published in Ophthalmology (Rochester, Minn.) (01.09.2016)
Get full text
Journal Article
Faster Sensitivity Loss around Dense Scotomas than for Overall Macular Sensitivity in Stargardt Disease: ProgStar Report No. 14
Ibrahim, Mohamed A., Muñoz, Beatriz, Ip, Michael S., Sadda, SriniVas R., Scholl, Hendrik P.N., Strauss, Rupert W., Bittencourt, Millena, Schönbach, Etienne, Traboulsi, Elias, Ehlers, Justis, Briggs, Rachael, Borer, Angela, Burgnoni, Nikki, Sunness, Janet S., Russell, Leslie, Michaelides, Michel, Moore, Anthony, Barnfield, Jade, Salchi, Zaid, McCudden, Victoria, Pefkianaki, Maria, Aboshiha, Jonathan, Holder, Graham, Robson, Anthony, Cajas Narvaez, Daniela Ivanova, Barnard, Katy, Dunbar, Hannah, Obadeyi, Yetunde, Girard-Claudon, Karine, Swann, Hilary, Bibi, Kanom, Georgiou, Anne, Sawyer, Briana Lauren, Creel, Donnel, Wang, Yi-Zhong, Locke, Kirsten, Jacobson, Samuel G., Schwartz, Sharon B., Zrenner, Eberhart, Nasser, Fadi, Wilhelm, Barbara, Koenig, Tilman, Sahel, José-Alain, Laurent-Coriat, Caroline, Sliesoraityte, Ieva, Boyard, Fiona, Tran, Minh Ha, Amaudruz, Juliette, Girmens, Aurore, Wojciechowski, Robert, Khan, Shazia, Emmert, David G., Bassinger, Jennifer, Liberto, Lisa, West, Sheila, Ervin, Ann-Margret, Munoz, Beatriz, Dreger, Kurt, Sadda, Srinivas, Ip, Michael S., Kramer, Brendan, Lam, Ngoc, Tawdros, Rita, Zhou, Yong Dong, Hariri, Amirhossein, Lock, Amy, Ganegoda, Anushika, Petrossian, Christine, Jenkins, Dennis, Strnad, Edward, Ito, Eric, Samson, Feliz, Blanquel, Gloria, Melendez, Jhanisus, Huang, Jianyan, Chau, Jonathan, Li, Manfred, Mendoza, Maria, Nittala, Muneeswar Gupta, Pitetta, Sean, Balasubramanian, Siva, Leahy, Sophie, Srinivas, Sowmya J., Velaga, Swetha B., Tepelus, Tudor, Brown, Tyler, Shi, Yue, Aguilar, Katherine, Chan, Cynthia, Seo, Brian, Miyasato, Kelly, Higgins, Julia, Gonzalez, Norma, Ellenbogen, David, Sanford, Theo, Linares, Daisy, Chiguil, Vivian, Kim, Monica, Smith, Monika, Sarreal, Natalie
Published in American journal of ophthalmology (01.08.2020)
Published in American journal of ophthalmology (01.08.2020)
Get full text
Journal Article
Longitudinal Changes of Fixation Location and Stability Within 12 Months in Stargardt Disease: ProgStar Report No. 12
Strauss, Rupert W., Kong, Xiangrong, Muñoz, Beatriz, Hahn, Gesa-Astrid, Nasser, Fadi, Sadda, SriniVas R., Scholl, Hendrik P.N., Strauss, Rupert W., Wolfson, Yulia, Ahmed, Mohamed, Fujinami, Kaoru, Traboulsi, Elias, Ehlers, Justis, Marino, Meghan, Crowe, Susan, Pinter, Anne, Fecko, Tami, Burgnoni, Nikki, Applegate, Carol, Esposti, Simona Degli, Moore, Anthony, Webster, Andrew, Connor, Sophie, Barnfield, Jade, Alfageme, Clara, Aboshiha, Jonathan, Holder, Graham, Narvaez, Daniela Ivanova Cajas, Rughani, Avani, Amoah, Charles, Bibi, Kanom, Begum, Hamida, Lewism, Selma, Shaheen, Saddaf, Shinmar, Harpreet, Bernstein, Paul, Carlstrom, Bonnie, Fry, Cyrie, Chandler, Melissa, Birch, David, Wang, Yi-Zhong, Rodriguez, Luis, Klein, Martin, Schwartz, Sharon B., Matsui, Rodrigo, Gruzensky, Michaela, Roman, Alejandro J., Zrenner, Eberhart, Nasser, Fadi, Hahn, Gesa Astrid, Peters, Tobias, Kramer, Susanne, Sahel, José-Alain, Zeitz, Christina, Boyard, Fiona, Tran, Minh Ha, Chaumette, Céline, Cain, Dennis, Herring, Mark, Bassinger, Jennifer, Sadda, Srinivas, Jha, Anamika, Ho, Alex, Lock, Amy, Elshafei, Anthony, Jenkins, Dennis, Baghdasaryan, Elmira, Ito, Eric, Samson, Feliz, Blanquel, Gloria, Melendez, Jhanisus, Lei, Jianqin, Chau, Jonathan, Falavarjani, Khalil G., Espino, Kristina, Li, Manfred, Mendoza, Maria, Roded, Netali, Saleh, Nizar, Velaga, Swetha B., Margaryan, Teresa, Fan, Wenying, Murillo, Yamileth, Shi, Yue, Chan, Cynthia, Santos, Lisa, Seo, Brian, Perez, Silvia, Chao, Stephanie, Robledo, Vicky, Baker, Kirstie, Ellenbogen, David, Bluemel, Daniel, Linares, Daisy, Tran, Mei, Oberoi, Michelle, Romero, Mark, Bynum-Bain, Grantley, Mendiguren, Carolina, Huang, Xiwen
Published in American journal of ophthalmology (01.09.2018)
Published in American journal of ophthalmology (01.09.2018)
Get full text
Journal Article
Identification of Fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration
Ambati, Meenakshi, Apicella, Ivana, Narendran, Siddharth, Shao-Bin, Wang, Leung, Hannah, Pereira, Felipe, Varshney, Akhil, Baker, Kirstie L, Marion, Kenneth M, Shadmehr, Mehrdad, Stains, Cliff I, Sadda, Srinivas R, Taylor, Ethan W, Sutton, S Scott, Werner, Brian C, Magagnoli, Joseph, Gelfand, Bradley D
Published in bioRxiv (13.01.2021)
Published in bioRxiv (13.01.2021)
Get full text
Paper