Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer
Ren, Huiyu, Bakas, Nicole A, Vamos, Mitchell, Chaikuad, Apirat, Limpert, Allison S, Wimer, Carina D, Brun, Sonja N, Lambert, Lester J, Tautz, Lutz, Celeridad, Maria, Sheffler, Douglas J, Knapp, Stefan, Shaw, Reuben J, Cosford, Nicholas D. P
Published in Journal of medicinal chemistry (10.12.2020)
Published in Journal of medicinal chemistry (10.12.2020)
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Journal Article
Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia
Bata, Nicole, Chaikuad, Apirat, Bakas, Nicole A, Limpert, Allison S, Lambert, Lester J, Sheffler, Douglas J, Berger, Lena M, Liu, Guoxiong, Yuan, Cunxiang, Wang, Li, Peng, Yi, Dong, Jing, Celeridad, Maria, Layng, Fabiana, Knapp, Stefan, Cosford, Nicholas D. P
Published in Journal of medicinal chemistry (27.01.2022)
Published in Journal of medicinal chemistry (27.01.2022)
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Journal Article
Thiasyrbactins Induce Cell Death via Proteasome Inhibition in Multiple Myeloma Cells
Pierce, Marquicia R, Bakas, Nicole A, Pirrung, Michael C, Bachmann, André S
Published in Anticancer research (01.10.2018)
Published in Anticancer research (01.10.2018)
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Journal Article
마크로시클릭 ULK1/2 억제제
BAKAS NICOLE A, COSFORD NICHOLAS D.P, LIMPERT ALLISON S, BRUN SONJA N, SHAW REUBEN J
Year of Publication 18.11.2022
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Year of Publication 18.11.2022
Patent
ULK1/2 억제제를 이용한 단일 및 병용 요법
BAKAS NICOLE A, COSFORD NICHOLAS D.P, LIMPERT ALLISON S, BRUN SONJA N, VAMOS MITCHELL, SHAW REUBEN J
Year of Publication 21.11.2022
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Year of Publication 21.11.2022
Patent
ULK1/2 의 억제제 및 이의 사용 방법
BAKAS NICOLE A, COSFORD NICHOLAS D.P, LIMPERT ALLISON S, VAMOS MITCHELL, BRUN SONJA N, SHAW REUBEN J
Year of Publication 18.11.2022
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Year of Publication 18.11.2022
Patent
MACROCYCLIC ULK1/2 INHIBITORS
BRUN, Sonja N, BAKAS, Nicole A, SHAW, Reuben J, LIMPERT, Allison S, COSFORD, Nicholas D.P
Year of Publication 28.02.2024
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Year of Publication 28.02.2024
Patent
MONO AND COMBINATION THERAPIES WITH ULK1/2 INHIBITORS
BRUN, Sonja N, SHAW, Reuben J, BAKAS, Nicole A, LIMPERT, Allison S, VAMOS, Mitchell, COSFORD, Nicholas D.P
Year of Publication 06.03.2024
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Year of Publication 06.03.2024
Patent
INHIBITORS OF ULK1/2 AND METHODS OF USING SAME
BRUN, Sonja N, BAKAS, Nicole A, SHAW, Reuben J, VAMOS, Mitchell, LIMPERT, Allison S, COSFORD, Nicholas D.P
Year of Publication 21.02.2024
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Year of Publication 21.02.2024
Patent
MACROCYCLIC ULK1/2 INHIBITORS
BRUN, Sonja N, BAKAS, Nicole A, SHAW, Reuben J, LIMPERT, Allison S, COSFORD, Nicholas D.P
Year of Publication 30.03.2023
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Year of Publication 30.03.2023
Patent
MACROCYCLIC ULK1/2 INHIBITORS
BRUN, Sonja N, BAKAS, Nicole A, SHAW, Reuben J, LIMPERT, Allison S, COSFORD, Nicholas D.P
Year of Publication 21.12.2022
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Year of Publication 21.12.2022
Patent