The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody
Benson, Don M., Bakan, Courtney E., Mishra, Anjali, Hofmeister, Craig C., Efebera, Yvonne, Becknell, Brian, Baiocchi, Robert A., Zhang, Jianying, Yu, Jianhua, Smith, Megan K., Greenfield, Carli N., Porcu, Pierluigi, Devine, Steven M., Rotem-Yehudar, Rinat, Lozanski, Gerard, Byrd, John C., Caligiuri, Michael A.
Published in Blood (30.09.2010)
Published in Blood (30.09.2010)
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Elotuzumab directly enhances NK cell cytotoxicity against myeloma via CS1 ligation: evidence for augmented NK cell function complementing ADCC
Collins, Shauna M., Bakan, Courtney E., Swartzel, Gina D., Hofmeister, Craig C., Efebera, Yvonne A., Kwon, Hakju, Starling, Gary C., Ciarlariello, David, Bhaskar, Shakthi, Briercheck, Edward L., Hughes, Tiffany, Yu, Jianhua, Rice, Audie, Benson, Don M.
Published in Cancer Immunology, Immunotherapy (01.12.2013)
Published in Cancer Immunology, Immunotherapy (01.12.2013)
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Journal Article
IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect
Benson, Don M., Bakan, Courtney E., Zhang, Shuhong, Collins, Shauna M., Liang, Jing, Srivastava, Shivani, Hofmeister, Craig C., Efebera, Yvonne, Andre, Pascale, Romagne, Francois, Bléry, Mathieu, Bonnafous, Cécile, Zhang, Jianying, Clever, David, Caligiuri, Michael A., Farag, Sherif S.
Published in Blood (08.12.2011)
Published in Blood (08.12.2011)
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A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells
Lin, Li, Benson Jr, Don M., DeAngelis, Stephanie, Bakan, Courtney E., Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Published in International journal of cancer (15.03.2012)
Published in International journal of cancer (15.03.2012)
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Journal Article
Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines
Bill, Matthew A, Bakan, Courtney, Benson, Jr, Don M, Fuchs, James, Young, Gregory, Lesinski, Gregory B
Published in Molecular cancer therapeutics (01.09.2009)
Published in Molecular cancer therapeutics (01.09.2009)
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Journal Article
Recombinant interleukin‐2 in patients aged younger than 60 years with acute myeloid leukemia in first complete remission: Results from Cancer and Leukemia Group B 19808
Kolitz, Jonathan E., George, Stephen L., Benson, Don M., Maharry, Kati, Marcucci, Guido, Vij, Ravi, Powell, Bayard L., Allen, Steven L., DeAngelo, Daniel J., Shea, Thomas C., Stock, Wendy, Bakan, Courtney E., Hars, Vera, Hoke, Eva, Bloomfield, Clara D., Caligiuri, Michael A., Larson, Richard A.
Published in Cancer (01.04.2014)
Published in Cancer (01.04.2014)
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The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity
Bill, Matthew A, Fuchs, James R, Li, Chenglong, Yui, Jennifer, Bakan, Courtney, Benson, Jr, Don M, Schwartz, Eric B, Abdelhamid, Dalia, Lin, Jiayuh, Hoyt, Dale G, Fossey, Stacey L, Young, Gregory S, Carson, 3rd, William E, Li, Pui-Kai, Lesinski, Gregory B
Published in Molecular cancer (25.06.2010)
Published in Molecular cancer (25.06.2010)
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Journal Article
Expression of Concern: A small molecule, LLL12 inhibits constitutive STAT3 and IL‐6‐induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells
Lin, Li, Benson, Don M., DeAngelis, Stephanie, Bakan, Courtney E., Li, Pui‐Kai, Li, Chenglong, Lin, Jiayuh
Published in International journal of cancer (15.03.2012)
Published in International journal of cancer (15.03.2012)
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Journal Article
Effects of induction with novel agents versus conventional chemotherapy on mobilization and autologous stem cell transplant outcomes in multiple myeloma
Benson, Don M., Panzner, Kathryn, Hamadani, Mehdi, Hofmeister, Craig C., Bakan, Courtney E., Smith, Megan K., Elder, Pat, Krugh, David, O'Donnell, Lynn, Devine, Steven M.
Published in Leukemia & lymphoma (01.02.2010)
Published in Leukemia & lymphoma (01.02.2010)
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Journal Article
A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma
Benson, Don M., Hofmeister, Craig C., Padmanabhan, Swaminathan, Suvannasankha, Attaya, Jagannath, Sundar, Abonour, Rafat, Bakan, Courtney, Andre, Pascale, Efebera, Yvonne, Tiollier, Jérôme, Caligiuri, Michael A., Farag, Sherif S.
Published in Blood (22.11.2012)
Published in Blood (22.11.2012)
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Journal Article
First Interim Results of a Phase I/II Study of Lenalidomide in Combination with Anti-PD-1 Monoclonal Antibody MDV9300 (CT-011) in Patients with Relapsed/Refractory Multiple Myeloma
Efebera, Yvonne A., Rosko, Ashley E, Hofmeister, Craig, Benner, Joe, Bakan, Courtney, Stamper, Kathleen, Lamb, Tammy, Hollie, Devine, Sell, Megan, Avigan, David, Benson, Don M
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Curcumin Induces Pro-apoptotic Effects Against Human Melanoma Cells and Modulates The Cellular Response to Immunotherapeutic Cytokines
Bill, Matthew A., Bakan, Courtney, Benson, Don M., Fuchs, James, Young, Gregory, Lesinski, Gregory B.
Published in Molecular cancer therapeutics (01.09.2009)
Published in Molecular cancer therapeutics (01.09.2009)
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Journal Article
IPH2101, a Novel Anti-Inhibitory KIR Monoclonal Antibody for Multiple Myeloma: Interm Phase 1 Trial Results and Correlative Biologic and Safety Data
Benson, Don M, Bakan, Courtney E, Padmanaban, Swaminathan, Abonour, Rafat, Suvannasankha, Attaya, Jagannath, Sundar, Chari, Ajai, Clever, David, Kalu, Chidimma, Collins, Shauna, Alghothani, Yousef, Hofmeister, Craig C., Efebera, Yvonne, Blanchet, Stephane, Caligiuri, Michael A., Farag, Sherif
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Journal Article
Characterization of Early Natural Killer Cell Reconstitution Following Autologous Transplantation in Multiple Myeloma
Benson, Don, Bakan, Courtney E, Alghothani, Lana, Hofmeister, Craig C., Efebera, Yvonne A, Smith, Megan K, Greenfield, Carli N, Andre, Pascale, Squiban, Patrick, Romagne, Francois, Caligiuri, Michael A., Devine, Steven M
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article
Novel Monoclonal Antibody Enhances Natural Killer (NK) Cell Cytotoxicity against Multiple Myeloma (MM): Interim Phase 1 Trial Results
Benson, Don, Hofmeister, Craig C., Padmanabhan, Swaminathan, Abonour, Rafat, Suvannasankha, Attaya, Mita, Alain, Squiban, Patrick, Smith, Megan K, Bakan, Courtney E, Marzetto, Marc, Andre, Pascale, Tollier, Jerome, Caligiuri, Michael A., Farag, Sherif
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article
IPH2101, a Novel Anti-Inhibitory KIR Monoclonal Antibody, and Lenalidomide Combine to Enhance the Natural Killer (NK) Cell Versus Multiple Myeloma (MM) Effect
Benson, Don, Bakan, Courtney E, Zhang, Shuhong, Alghothani, Lana, Liang, Jing, Hofmeister, Craig, Srivastava, Shivani, Smith, Megan K, Greenfield, Carli N, Andre, Pascale, Squiban, Patrick, Romagne, Francois, Caligiuri, Michael A., Farag, Sherif
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article