Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption
Pfefferkorn, Jeffrey A., Larsen, Scott D., Huis, Chad Van, Sorenson, Roderick, Barton, Tom, Winters, Thomas, Auerbach, Bruce, Wu, Chenyan, Wolfram, Thaddeus J., Cai, Hongliang, Welch, Kathleen, Esmaiel, Nadia, Davis, JoAnn, Bousley, Richard, Olsen, Karl, Mueller, Sandra Bak, Mertz, Thomas
Published in Bioorganic & medicinal chemistry (15.01.2008)
Published in Bioorganic & medicinal chemistry (15.01.2008)
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Journal Article
The ACAT Inhibitor Avasimibe Reduces Macrophages and Matrix Metalloproteinase Expression in Atherosclerotic Lesions of Hypercholesterolemic Rabbits
Bocan, Thomas M. A, Krause, Brian R, Rosebury, Wendy S, Mueller, Sandra Bak, Lu, Xiaokang, Dagle, Catherine, Major, Terry, Lathia, Chetan, Lee, Helen
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2000)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2000)
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Journal Article
Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice
Park, Tae-Sik, Panek, Robert L, Mueller, Sandra Bak, Hanselman, Jeffrey C, Rosebury, Wendy S, Robertson, Andrew W, Kindt, Erick K, Homan, Reynold, Karathanasis, Sotirios K, Rekhter, Mark D
Published in Circulation (New York, N.Y.) (30.11.2004)
Published in Circulation (New York, N.Y.) (30.11.2004)
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Journal Article
A specific 15-lipoxygenase inhibitor limits the progression and monocyte–macrophage enrichment of hypercholesterolemia-induced atherosclerosis in the rabbit
Bocan, Thomas M.A, Rosebury, Wendy S, Mueller, Sandra Bak, Susan Kuchera, Welch, Kathryn, Daugherty, Alan, Cornicelli, Joseph A
Published in Atherosclerosis (01.02.1998)
Published in Atherosclerosis (01.02.1998)
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Journal Article
The combined effect of inhibiting both ACAT and HMG-CoA reductase may directly induce atherosclerotic lesion regression
Bocan, Thomas M.A, Krause, Brian R, Rosebury, Wendy S, Lu, Xiaokang, Dagle, Catherine, Bak Mueller, Sandra, Auerbach, Bruce, Sliskovic, D.Robert
Published in Atherosclerosis (01.07.2001)
Published in Atherosclerosis (01.07.2001)
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Journal Article
The relationship between the degree of dietary-induced hypercholesterolemia in the rabbit and atherosclerotic lesion formation
Bocan, Thomas M.A., Bak Mueller, Sandra, Mazur, Michelle J., Uhlendorf, Paul D., Quenby Brown, Edie, Kieft, Karen A.
Published in Atherosclerosis (01.08.1993)
Published in Atherosclerosis (01.08.1993)
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Journal Article
Antiatherosclerotic activity of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase in cholesterol-fed rabbits: a biochemical and morphological evaluation
Bocan, Thomas M.A., Mazur, Michelle J., Bak Mueller, Sandra, Brown, Edie Quenby, Sliskovic, D.Robert, O'Brien, Patrick M., Creswell, Mark W., Lee, Helen, Uhlendorf, Paul D., Roth, Bruce D., Newton, Roger S.
Published in Atherosclerosis (01.11.1994)
Published in Atherosclerosis (01.11.1994)
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Journal Article
Heterocyclic Amides: Inhibitors of Acyl-CoA:Cholesterol O-Acyl Transferase with Hypocholesterolemic Activity in Several Species and Antiatherosclerotic Activity in the Rabbit
White, Andrew D, Purchase, Claude F, Picard, Joseph A, Anderson, Maureen K, Bak Mueller, Sandra, Bocan, Thomas M. A, Bousley, Richard F, Hamelehle, Katherine L, Krause, Brian R, Lee, Peter, Stanfield, Richard L, Reindel, James F
Published in Journal of medicinal chemistry (27.09.1996)
Published in Journal of medicinal chemistry (27.09.1996)
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Journal Article
Modulation of lipoprotein metabolism by inhibition of sphingomyelin synthesis in ApoE knockout mice
Park, Tae-Sik, Panek, Robert L., Rekhter, Mark D., Mueller, Sandra Bak, Rosebury, Wendy S., Robertson, Andrew, Hanselman, Jeffrey C., Kindt, Erick, Homan, Reynold, Karathanasis, Sotirios K.
Published in Atherosclerosis (01.12.2006)
Published in Atherosclerosis (01.12.2006)
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Journal Article
Tetrazole-substituted ureas as inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT). A novel preparation of ureas from weakly nucleophilic amines
Purchase, Claude F, White, Andrew D, Anderson, Maureen K, Bocan, Thomas M.A, Bousley, Richard F, Hamelehle, Katherine L, Homan, Reynold, Krause, Brian R, Lee, Peter, Mueller, Sandra Bak, Speyer, Cecilia, Stanfield, Richard L, Reindel, James F
Published in Bioorganic & medicinal chemistry letters (06.08.1996)
Published in Bioorganic & medicinal chemistry letters (06.08.1996)
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Journal Article
Atherosclerosis in Octodon degus (degu) as a model for human disease
Homan, Reynold, Hanselman, Jeffrey C, Bak-Mueller, Sandra, Washburn, Michelle, Lester, Patrick, Jensen, Heather E, Pinkosky, Stephen L, Castle, Christine, Taylor, Bruce
Published in Atherosclerosis (01.09.2010)
Published in Atherosclerosis (01.09.2010)
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Journal Article
Dietary and mechanically induced rabbit Iliac-femoral atherosclerotic lesions: A chemical and morphologic evaluation
Bocan, Thomas M.A., Mueller, Sandra Bak, Uhlendorf, Paul D., Ferguson, Erika, Newton, Roger S.
Published in Experimental and molecular pathology (01.06.1991)
Published in Experimental and molecular pathology (01.06.1991)
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Journal Article
Quantitative sphingosine measurement as a surrogate for total ceramide concentration-preclinical and potential translational applications
Kindt, Erick, Wetterau, John, Mueller, Sandra Bak, Castle, Christine, Boustany-Kari, Carine M.
Published in Biomedical chromatography (01.07.2010)
Published in Biomedical chromatography (01.07.2010)
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Journal Article
HMG-CoA reductase and ACAT inhibitors act synergistically to lower plasma cholesterol and limit atherosclerotic lesion development in the cholesterol-fed rabbit
Bocan, Thomas M.A, Bak Mueller, Sandra, Quenby Brown, Edie, Lee, Peter, Bocan, Michelle J, Rea, Thomas, Pape, Michael E
Published in Atherosclerosis (01.07.1998)
Published in Atherosclerosis (01.07.1998)
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Journal Article
The ACAT inhibitor Avasimible reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits
Bocan, Thomas M A, Krause, Brian R, Rosebury, Wendy S, Sandra Bak Mueller
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2000)
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Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2000)
Journal Article
Inhibitors of Acyl-CoA:Cholesterol O-Acyltransferase. Synthesis and Pharmacological Activity of (±)-2-Dodecyl-α-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5-acetamide and Structurally Related Tetrazole Amide Derivatives
O'Brien, Patrick M, Sliskovic, Drago R, Picard, Joseph A, Lee, Helen T, Purchase, Claude F, Roth, Bruce D, White, Andrew D, Anderson, Maureen, Mueller, Sandra Bak, Bocan, Thomas, Bousley, Richard, Hamelehle, Katherine L, Homan, Reynold, Lee, Peter, Krause, Brian R, Reindel, J. F, Turluck, Daniel
Published in Journal of medicinal chemistry (07.06.1996)
Published in Journal of medicinal chemistry (07.06.1996)
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Journal Article
α-Substituted Malonester Amides: Tools To Define the Relationship between ACAT Inhibition and Adrenal Toxicity
Sliskovic, Drago R, Picard, Joseph A, O'Brien, Patrick M, Liao, Peggy, Roark, W. Howard, Roth, Bruce D, Anderson, Maureen A, Mueller, Sandra Bak, Bocan, Thomas M. A, Bousley, Richard F, Hamelehle, Katherine L, Homan, Reynold, Reindel, James F, Stanfield, Richard L, Turluck, Daniel, Krause, Brian R
Published in Journal of medicinal chemistry (26.02.1998)
Published in Journal of medicinal chemistry (26.02.1998)
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Journal Article
Inhibition of acyl-CoA cholesterol O-acyltransferase reduces the cholesteryl ester enrichment of atherosclerotic lesions in the Yucatan micropig
Bocan, Thomas M.A., Mueller, Sandra Bak, Uhlendorf, Paul D., Brown, Edie Quenby, Mazur, Michelle J., Black, Ann E.
Published in Atherosclerosis (01.03.1993)
Published in Atherosclerosis (01.03.1993)
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Journal Article
Inhibitors of Acyl-CoA:Cholesterol O -Acyltransferase. Synthesis and Pharmacological Activity of (±)-2-Dodecyl-α-phenyl- N -(2,4,6-trimethoxyphenyl)-2 H -tetrazole-5-acetamide and Structurally Related Tetrazole Amide Derivatives
O'Brien, Patrick M., Sliskovic, Drago R., Picard, Joseph A., Lee, Helen T., Purchase, Claude F., Roth, Bruce D., White, Andrew D., Anderson, Maureen, Mueller, Sandra Bak, Bocan, Thomas, Bousley, Richard, Hamelehle, Katherine L., Homan, Reynold, Lee, Peter, Krause, Brian R., Reindel, J. F., Richard L. Stanfield, and, Turluck, Daniel
Published in Journal of medicinal chemistry (01.01.1996)
Published in Journal of medicinal chemistry (01.01.1996)
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Journal Article
Antiatherosclerotic effects of antioxidants are lesion-specific when evaluated in hypercholesterolemic New Zealand White rabbits
Bocan, Thomas M.A., Mueller, Sandra Bak, Brown, Edie Quenby, Uhlendorf, Paul D., Mazur, Michelle J., Newton, Roger S.
Published in Experimental and molecular pathology (01.08.1992)
Published in Experimental and molecular pathology (01.08.1992)
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Journal Article