Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis
Schafer, PH, Parton, A, Gandhi, AK, Capone, L, Adams, M, Wu, L, Bartlett, JB, Loveland, MA, Gilhar, A, Cheung, Y‐F, Baillie, GS, Houslay, MD, Man, H‐W, Muller, GW, Stirling, DI
Published in British journal of pharmacology (01.02.2010)
Published in British journal of pharmacology (01.02.2010)
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The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells
Henderson, D J P, Byrne, A, Dulla, K, Jenster, G, Hoffmann, R, Baillie, G S, Houslay, M D
Published in British journal of cancer (04.03.2014)
Published in British journal of cancer (04.03.2014)
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β-Arrestin 1 Inhibits the GTPase-Activating Protein Function of ARHGAP21, Promoting Activation of RhoA following Angiotensin II Type 1A Receptor Stimulation
Anthony, D. F., Sin, Y. Y., Vadrevu, S., Advant, N., Day, J. P., Byrne, A. M., Lynch, M. J., Milligan, G., Houslay, M. D., Baillie, G. S.
Published in Molecular and Cellular Biology (01.03.2011)
Published in Molecular and Cellular Biology (01.03.2011)
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The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon‐like peptide‐1 release
Ong, WK, Gribble, FM, Reimann, F, Lynch, MJ, Houslay, MD, Baillie, GS, Furman, BL, Pyne, NJ
Published in British journal of pharmacology (01.06.2009)
Published in British journal of pharmacology (01.06.2009)
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Production of extracellular matrix by Candida albicans biofilms
Hawser, S. P, Baillie, G. S, Douglas, L. Julia
Published in Journal of medical microbiology (01.03.1998)
Published in Journal of medical microbiology (01.03.1998)
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FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system
Yalla, K, Elliott, C, Day, J P, Findlay, J, Barratt, S, Hughes, Z A, Wilson, L, Whiteley, E, Popiolek, M, Li, Y, Dunlop, J, Killick, R, Adams, D R, Brandon, N J, Houslay, M D, Hao, B, Baillie, G S
Published in Molecular psychiatry (01.05.2018)
Published in Molecular psychiatry (01.05.2018)
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Phosphorylation of PDE4A5 by MAPKAPK2 attenuates fibrin degradation via p75 signalling
Houslay, K F, Fertig, B A, Christian, F, Tibbo, A J, Ling, J, Findlay, J E, Houslay, M D, Baillie, G S
Published in Journal of biochemistry (Tokyo) (01.07.2019)
Published in Journal of biochemistry (Tokyo) (01.07.2019)
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Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes
Sin, Y.Y, Edwards, H.V, Li, X, Day, J.P, Christian, F, Dunlop, A.J, Adams, D.R, Zaccolo, M, Houslay, M.D, Baillie, G.S
Published in Journal of molecular and cellular cardiology (01.05.2011)
Published in Journal of molecular and cellular cardiology (01.05.2011)
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Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG-positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression
Böttcher, R, Henderson, D J P, Dulla, K, van Strijp, D, Waanders, L F, Tevz, G, Lehman, M L, Merkle, D, van Leenders, G J L H, Baillie, G S, Jenster, G, Houslay, M D, Hoffmann, R
Published in British journal of cancer (17.11.2015)
Published in British journal of cancer (17.11.2015)
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Phosphodiesterase 4 interacts with the 5-HT4(b) receptor to regulate cAMP signaling
Weninger, S., Van Craenenbroeck, K., Cameron, R.T., Vandeput, F., Movsesian, M.A., Baillie, G.S., Lefebvre, R.A.
Published in Cellular signalling (01.11.2014)
Published in Cellular signalling (01.11.2014)
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Mixed species biofilms of Candida albicans and Staphylococcus epidermidis
ADAM, BERIT, BAILLIE, GEORGE S, DOUGLAS, L. JULIA
Published in Journal of medical microbiology (01.04.2002)
Published in Journal of medical microbiology (01.04.2002)
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cAMP phosphodiesterase-4A1 (PDE4A1) has provided the paradigm for the intracellular targeting of phosphodiesterases, a process that underpins compartmentalized cAMP signalling
Huston, E, Houslay, T M, Baillie, G S, Houslay, M D
Published in Biochemical Society transactions (01.08.2006)
Published in Biochemical Society transactions (01.08.2006)
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