Second-Generation Live-Attenuated Candid#1 Vaccine Virus Resists Reversion and Protects against Lethal Junín Virus Infection in Guinea Pigs
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Published in Journal of virology (24.06.2021)
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Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections
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Published in Nature communications (28.01.2022)
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In Vitro and In Vivo Activities of T-705 against Arenavirus and Bunyavirus Infections
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Published in Antimicrobial Agents and Chemotherapy (01.09.2007)
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Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses
Westover, Jonna B., Sefing, Eric J., Bailey, Kevin W., Van Wettere, Arnaud J., Jung, Kie-Hoon, Dagley, Ashley, Wandersee, Luci, Downs, Brittney, Smee, Donald F., Furuta, Yousuke, Bray, Mike, Gowen, Brian B.
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Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice
SMEE, Donald F, HURST, Brett L, WONG, Min-Hui, BAILEY, Kevin W, BART TARBET, E, MORREY, John D, FURUTA, Yousuke
Published in Antimicrobial Agents and Chemotherapy (01.01.2010)
Published in Antimicrobial Agents and Chemotherapy (01.01.2010)
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Type I interferon underlies severe disease associated with Junín virus infection in mice
Hickerson, Brady T, Sefing, Eric J, Bailey, Kevin W, Van Wettere, Arnaud J, Penichet, Manuel L, Gowen, Brian B
Published in eLife (26.05.2020)
Published in eLife (26.05.2020)
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Efficacy of Orally Administered T-705 on Lethal Avian Influenza A (H5N1) Virus Infections in Mice
SIDWELL, Robert W, BARNARD, Dale L, DAY, Craig W, SMEE, Donald F, BAILEY, Kevin W, WONG, Min-Hui, MORREY, John D, FURUTA, Yousuke
Published in Antimicrobial Agents and Chemotherapy (01.03.2007)
Published in Antimicrobial Agents and Chemotherapy (01.03.2007)
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Enhanced protection against experimental Junin virus infection through the use of a modified favipiravir loading dose strategy
Gowen, Brian B., Westover, Jonna B., Sefing, Eric J., Van Wettere, Arnaud J., Bailey, Kevin W., Wandersee, Luci, Komeno, Takashi, Furuta, Yousuke
Published in Antiviral research (01.09.2017)
Published in Antiviral research (01.09.2017)
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Effects of Double Combinations of Amantadine, Oseltamivir, and Ribavirin on Influenza A (H5N1) Virus Infections in Cell Culture and in Mice
SMEE, Donald F, HURST, Brett L, WONG, Min-Hui, BAILEY, Kevin W, MORREY, John D
Published in Antimicrobial Agents and Chemotherapy (01.05.2009)
Published in Antimicrobial Agents and Chemotherapy (01.05.2009)
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Rift Valley fever virus infection in golden Syrian hamsters
Scharton, Dionna, Van Wettere, Arnaud J, Bailey, Kevin W, Vest, Zachary, Westover, Jonna B, Siddharthan, Venkatraman, Gowen, Brian B
Published in PloS one (21.01.2015)
Published in PloS one (21.01.2015)
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Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin
Kumaki, Yohichi, Wandersee, Miles K., Smith, Aaron J., Zhou, Yanchen, Simmons, Graham, Nelson, Nathan M., Bailey, Kevin W., Vest, Zachary G., Li, Joseph K.-K., Chan, Paul Kay-Sheung, Smee, Donald F., Barnard, Dale L.
Published in Antiviral research (01.04.2011)
Published in Antiviral research (01.04.2011)
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Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin
Gowen, Brian B, Smee, Donald F, Wong, Min-Hui, Hall, Jeffery O, Jung, Kie-Hoon, Bailey, Kevin W, Stevens, John R, Furuta, Yousuke, Morrey, John D
Published in PloS one (14.11.2008)
Published in PloS one (14.11.2008)
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MP-12 virus containing the clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters
Gowen, Brian B, Westover, Jonna B, Sefing, Eric J, Bailey, Kevin W, Nishiyama, Shoko, Wandersee, Luci, Scharton, Dionna, Jung, Kie-Hoon, Ikegami, Tetsuro
Published in Frontiers in microbiology (29.06.2015)
Published in Frontiers in microbiology (29.06.2015)
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Single-dose intranasal treatment with DEF201 (adenovirus vectored consensus interferon) prevents lethal disease due to Rift Valley fever virus challenge
Gowen, Brian B, Ennis, Jane, Bailey, Kevin W, Vest, Zachary, Scharton, Dionna, Sefing, Eric J, Turner, Jeffrey D
Published in Viruses (24.03.2014)
Published in Viruses (24.03.2014)
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Restoration of virulence in the attenuated Candid#1 vaccine virus requires reversion at both positions 168 and 427 in the envelope glycoprotein GPC
Nunberg, Jack H, Westover, Jonna B, York, Joanne, Jung, Kie Hoon, Bailey, Kevin W, Boardman, Kirsten M, Li, Minghao, Furnell, Rachel S, Wasson, Samantha R, Murray, Justin S, Kaundal, Rakesh, Thomas, Aaron J, Gowen, Brian B
Published in Journal of virology (16.04.2024)
Published in Journal of virology (16.04.2024)
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Severe mammarenaviral disease in guinea pigs effectively treated by an orally bioavailable fusion inhibitor, alone or in combination with favipiravir
Westover, Jonna B., Naik, Shibani, Bailey, Kevin W., Wandersee, Luci, Gantla, Vidyasagar R., Hickerson, Brady T., McCormack, Ken, Henkel, Greg, Gowen, Brian B.
Published in Antiviral research (01.12.2022)
Published in Antiviral research (01.12.2022)
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Coadministration of LHF-535 and favipiravir protects against experimental Junín virus infection and disease
Westover, Jonna B., Bailey, Kevin W., Wasson, Samantha R., Boardman, Kirsten M., Lustig, Kurt H., Amberg, Sean M., Gowen, Brian B.
Published in Antiviral research (01.09.2024)
Published in Antiviral research (01.09.2024)
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Favipiravir (T-705) protects against peracute Rift Valley fever virus infection and reduces delayed-onset neurologic disease observed with ribavirin treatment
Scharton, Dionna, Bailey, Kevin W., Vest, Zachary, Westover, Jonna B., Kumaki, Yohichi, Van Wettere, Arnaud, Furuta, Yousuke, Gowen, Brian B.
Published in Antiviral research (01.04.2014)
Published in Antiviral research (01.04.2014)
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Estimation of the Minimal Rift Valley Fever Virus Protective Neutralizing Antibody Titer in Human Volunteers Immunized with MP-12 Vaccine Based on Protection in a Mouse Model of Disease
Watts, Douglas M, Westover, Jonna L B, Palermo, Pedro M, Bailey, Kevin W, Morrill, John C, Bettinger, George E, Monath, Thomas P, Smith, Darci R, Peters, Clarence J, Pittman, Phillip R, Orbegozo, Jeanette, Gowen, Brian B
Published in The American journal of tropical medicine and hygiene (14.11.2022)
Published in The American journal of tropical medicine and hygiene (14.11.2022)
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