Synthesis of Sulfones from Organozinc Reagents, DABSO, and Alkyl Halides
Rocke, Benjamin N, Bahnck, Kevin B, Herr, Michael, Lavergne, Sophie, Mascitti, Vincent, Perreault, Christian, Polivkova, Jana, Shavnya, Andrei
Published in Organic letters (03.01.2014)
Published in Organic letters (03.01.2014)
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Formal Synthesis of (−)-Kendomycin Featuring a Prins-Cyclization To Construct the Macrocycle
Bahnck, Kevin B, Rychnovsky, Scott D
Published in Journal of the American Chemical Society (01.10.2008)
Published in Journal of the American Chemical Society (01.10.2008)
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Spirolactam-Based Acetyl-CoA Carboxylase Inhibitors: Toward Improved Metabolic Stability of a Chromanone Lead Structure
Griffith, David A, Dow, Robert L, Huard, Kim, Edmonds, David J, Bagley, Scott W, Polivkova, Jana, Zeng, Dongxiang, Garcia-Irizarry, Carmen N, Southers, James A, Esler, William, Amor, Paul, Loomis, Kathrine, McPherson, Kirk, Bahnck, Kevin B, Préville, Cathy, Banks, Tereece, Moore, Dianna E, Mathiowetz, Alan M, Menhaji-Klotz, Elnaz, Smith, Aaron C, Doran, Shawn D, Beebe, David A, Dunn, Matthew F
Published in Journal of medicinal chemistry (12.09.2013)
Published in Journal of medicinal chemistry (12.09.2013)
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Discovery of Selective Small Molecule Inhibitors of Monoacylglycerol Acyltransferase 3
Huard, Kim, Londregan, Allyn T, Tesz, Gregory, Bahnck, Kevin B, Magee, Thomas V, Hepworth, David, Polivkova, Jana, Coffey, Steven B, Pabst, Brandon A, Gosset, James R, Nigam, Anu, Kou, Kou, Sun, Hao, Lee, Kyuha, Herr, Michael, Boehm, Markus, Carpino, Philip A, Goodwin, Bryan, Perreault, Christian, Li, Qifang, Jorgensen, Csilla C, Tkalcevic, George T, Subashi, Timothy A, Ahn, Kay
Published in Journal of medicinal chemistry (24.09.2015)
Published in Journal of medicinal chemistry (24.09.2015)
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Design and Synthesis of Diazatricyclodecane Agonists of the G‑Protein-Coupled Receptor 119
Darout, Etzer, Robinson, Ralph P, McClure, Kim F, Corbett, Matthew, Li, Bryan, Shavnya, Andrei, Andrews, Melissa P, Jones, Christopher S, Li, Qifang, Minich, Martha L, Mascitti, Vincent, Guimarães, Cristiano R. W, Munchhof, Michael J, Bahnck, Kevin B, Cai, Cuiman, Price, David A, Liras, Spiros, Bonin, Paul D, Cornelius, Peter, Wang, Ruduan, Bagdasarian, Victoria, Sobota, Colleen P, Hornby, Sam, Masterson, Victoria M, Joseph, Reena M, Kalgutkar, Amit S, Chen, Yue
Published in Journal of medicinal chemistry (10.01.2013)
Published in Journal of medicinal chemistry (10.01.2013)
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Bond Insertion, Complexation, and Penetration Pathways of Vapor-Deposited Aluminum Atoms with HO- and CH3O-Terminated Organic Monolayers
Fisher, Gregory L., Walker, Amy V., Hooper, Andrew E., Tighe, Timothy B., Bahnck, Kevin B., Skriba, Hope T., Reinard, Michael D., Haynie, Brendan C., Opila, Robert L., Winograd, Nicholas, Allara, David L.
Published in Journal of the American Chemical Society (15.05.2002)
Published in Journal of the American Chemical Society (15.05.2002)
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Exploratory Process Development of a Novel Diacylglycerol Acyltransferase‑1 (DGAT-1) Inhibitor
Shavnya, Andrei, Tao, Yong, Lilley, Susan C, Bahnck, Kevin B, Munchhof, Michael J, Nematalla, Asaad, Waldo, Michael, Bill, David R
Published in Organic process research & development (20.12.2013)
Published in Organic process research & development (20.12.2013)
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Optimization of triazole-based TGR5 agonists towards orally available agents
Futatsugi, Kentaro, Bahnck, Kevin B., Brenner, Martin B., Buxton, Joanne, Chin, Janice E., Coffey, Steven B., Dubins, Jeffrey, Flynn, Declan, Gautreau, Denise, Guzman-Perez, Angel, Hadcock, John R., Hepworth, David, Herr, Michael, Hinchey, Terri, Janssen, Ann M., Jennings, Sandra M., Jiao, Wenhua, Lavergne, Sophie Y., Li, Bryan, Li, Mei, Munchhof, Michael J., Orr, Suvi T. M., Piotrowski, David W., Roush, Nicole S., Sammons, Matthew, Stevens, Benjamin D., Storer, Gregory, Wang, Jian, Warmus, Joseph S., Wei, Liuqing, Wolford, Angela C.
Published in MedChemComm (2013)
Published in MedChemComm (2013)
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Efficient Synthesis of 4-Amino-2-methoxy-7,8-dihydropyrido[4,3-d]pyrimidin-5-ones: Practical Access to a Novel Chemotype in the Development of DGAT-1 Inhibitors
Bahnck, Kevin B., Shavnya, Andrei, Tao, Yong, Lilley, Susan C., Andrews, Melissa P., Aspnes, Gary E., Bernhardson, David J., Bill, David R., Bundesmann, Mark W., Dow, Robert L., Karki, Kapil, Le, Tung, Li, Qifang, Munchhof, Michael J., Nematalla, Asaad, Nihlawi, Mohammed, Patel, Leena, Perreault, Christian, Waldo, Michael
Published in Synthesis (Stuttgart) (18.10.2012)
Published in Synthesis (Stuttgart) (18.10.2012)
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Piperazinyl CCR1 antagonists—optimization of human liver microsome stability
Brown, Matthew F., Bahnck, Kevin B., Blumberg, Laura C., Brissette, William H., Burrell, Sara A., Driscoll, James P., Fedeles, Flavia, Fisher, Michael B., Foti, Robert S., Gladue, Ronald P., Guzman-Martinez, Aikomari, Hayward, Matthew M., Lira, Paul D., Lillie, Brett M., Lu, Yi, Lundquist, Greg D., McElroy, Eric B., McGlynn, Molly A., Paradis, Timothy J., Poss, Christopher S., Roache, James H., Shavnya, Andrei, Shepard, Richard M., Trevena, Kristen A., Tylaska, Laurie A.
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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ChemInform Abstract: Synthesis of Sulfones from Organozinc Reagents, DABSO, and Alkyl Halides
Rocke, Benjamin N., Bahnck, Kevin B., Herr, Michael, Lavergne, Sophie, Mascitti, Vincent, Perreault, Christian, Polivkova, Jana, Shavnya, Andrei
Published in ChemInform (10.06.2014)
Published in ChemInform (10.06.2014)
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Optimization of triazole-based TGR5 agonists towards orally available agentsElectronic supplementary information (ESI) available: Detailed experimental procedures for synthesis of compounds 4, 10-18, a dataset of compounds 2-9 used for a plot in Fig. 2, and protocols for cAMP assays, human whole blood assay, and in vivo dog PK studies. See DOI: 10.1039/c2md20174g
Futatsugi, Kentaro, Bahnck, Kevin B, Brenner, Martin B, Buxton, Joanne, Chin, Janice E, Coffey, Steven B, Dubins, Jeffrey, Flynn, Declan, Gautreau, Denise, Guzman-Perez, Angel, Hadcock, John R, Hepworth, David, Herr, Michael, Hinchey, Terri, Janssen, Ann M, Jennings, Sandra M, Jiao, Wenhua, Lavergne, Sophie Y, Li, Bryan, Li, Mei, Munchhof, Michael J, Orr, Suvi T. M, Piotrowski, David W, Roush, Nicole S, Sammons, Matthew, Stevens, Benjamin D, Storer, Gregory, Wang, Jian, Warmus, Joseph S, Wei, Liuqing, Wolford, Angela C
Year of Publication 20.12.2012
Year of Publication 20.12.2012
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Journal Article
Bond insertion, complexation, and penetration pathways of vapor-deposited aluminum atoms with HO- and CH(3)O-terminated organic monolayers
Fisher, Gregory L, Walker, Amy V, Hooper, Andrew E, Tighe, Timothy B, Bahnck, Kevin B, Skriba, Hope T, Reinard, Michael D, Haynie, Brendan C, Opila, Robert L, Winograd, Nicholas, Allara, David L
Published in Journal of the American Chemical Society (15.05.2002)
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Published in Journal of the American Chemical Society (15.05.2002)
Journal Article
Bond Insertion, Complexation, and Penetration Pathways of Vapor-Deposited Aluminum Atoms with HO- and CH 3 O-Terminated Organic Monolayers
Fisher, Gregory L., Walker, Amy V., Hooper, Andrew E., Tighe, Timothy B., Bahnck, Kevin B., Skriba, Hope T., Reinard, Michael D., Haynie, Brendan C., Opila, Robert L., Winograd, Nicholas, Allara, David L.
Published in Journal of the American Chemical Society (01.05.2002)
Published in Journal of the American Chemical Society (01.05.2002)
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Journal Article