Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial
Murphy, Janet E, Wo, Jennifer Y, Ryan, David P, Clark, Jeffrey W, Jiang, Wenqing, Yeap, Beow Y, Drapek, Lorraine C, Ly, Leilana, Baglini, Christian V, Blaszkowsky, Lawrence S, Ferrone, Cristina R, Parikh, Aparna R, Weekes, Colin D, Nipp, Ryan D, Kwak, Eunice L, Allen, Jill N, Corcoran, Ryan B, Ting, David T, Faris, Jason E, Zhu, Andrew X, Goyal, Lipika, Berger, David L, Qadan, Motaz, Lillemoe, Keith D, Talele, Nilesh, Jain, Rakesh K, DeLaney, Thomas F, Duda, Dan G, Boucher, Yves, Fernández-Del Castillo, Carlos, Hong, Theodore S
Published in JAMA oncology (01.07.2019)
Published in JAMA oncology (01.07.2019)
Get more information
Journal Article
Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ)
Liu, Heng-Jia, Lam, Hilaire C., Baglini, Christian V., Nijmeh, Julie, Cottrill, Alischer A., Chan, Stephen Y., Henske, Elizabeth P.
Published in Oncogene (05.12.2019)
Published in Oncogene (05.12.2019)
Get full text
Journal Article
p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis
Lam, Hilaire C, Baglini, Christian V, Lope, Alicia Llorente, Parkhitko, Andrey A, Liu, Heng-Jia, Alesi, Nicola, Malinowska, Izabela A, Ebrahimi-Fakhari, Darius, Saffari, Afshin, Yu, Jane J, Pereira, Ana, Khabibullin, Damir, Ogorek, Barbara, Nijmeh, Julie, Kavanagh, Taylor, Handen, Adam, Chan, Stephen Y, Asara, John M, Oldham, William M, Diaz-Meco, Maria T, Moscat, Jorge, Sahin, Mustafa, Priolo, Carmen, Henske, Elizabeth P
Published in Cancer research (Chicago, Ill.) (15.06.2017)
Published in Cancer research (Chicago, Ill.) (15.06.2017)
Get full text
Journal Article
Correction: p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis
Lam, Hilaire C., Baglini, Christian V., Lope, Alicia Llorente, Parkhitko, Andrey A., Liu, Heng-Jia, Alesi, Nicola, Malinowska, Izabela A., Ebrahimi-Fakhari, Darius, Saffari, Afshin, Yu, Jane J., Pereira, Ana, Khabibullin, Damir, Ogorek, Barbara, Nijmeh, Julie, Kavanagh, Taylor, Handen, Adam, Chan, Stephen Y., Asara, John M., Oldham, William M., Diaz-Meco, Maria T., Moscat, Jorge, Sahin, Mustafa, Priolo, Carmen, Henske, Elizabeth P.
Published in Cancer research (Chicago, Ill.) (01.12.2020)
Published in Cancer research (Chicago, Ill.) (01.12.2020)
Get full text
Journal Article
Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells
Lam, Hilaire C, Liu, Heng-Jia, Baglini, Christian V, Filippakis, Harilaos, Alesi, Nicola, Nijmeh, Julie, Du, Heng, Lope, Alicia Llorente, Cottrill, Katherine A, Handen, Adam, Asara, John M, Kwiatkowski, David J, Ben-Sahra, Issam, Oldham, William M, Chan, Stephen Y, Henske, Elizabeth P
Published in Oncotarget (12.09.2017)
Published in Oncotarget (12.09.2017)
Get full text
Journal Article
mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
Valvezan, Alexander J., Turner, Marc, Belaid, Amine, Lam, Hilaire C., Miller, Spencer K., McNamara, Molly C., Baglini, Christian, Housden, Benjamin E., Perrimon, Norbert, Kwiatkowski, David J., Asara, John M., Henske, Elizabeth P., Manning, Brendan D.
Published in Cancer cell (13.11.2017)
Published in Cancer cell (13.11.2017)
Get full text
Journal Article
Abstract A28: Rapamycin-upregulated miR-29b promotes mTORC1-hyperactivative cell growth by downregulating retinoic acid receptor β (RARβ)
Liu, Heng-Jia, Lam, Hilaire C., Baglini, Christian V., Conttrill, Alex K., Chan, Stephen Y., Henske, Elizabeth P.
Published in Molecular cancer research (01.10.2020)
Published in Molecular cancer research (01.10.2020)
Get full text
Journal Article
Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor [beta]
Liu, Heng-Jia, Lam, Hilaire C, Baglini, Christian V, Nijmeh, Julie, Cottrill, Alischer A, Chan, Stephen Y, Henske, Elizabeth P
Published in Oncogene (05.12.2019)
Published in Oncogene (05.12.2019)
Get full text
Journal Article
From the ground up: recognising risk of frailty syndromes and functional decline through foot examination
James, Kirstyn, Baglini, Christian, Wershof Schwartz, Andrea
Published in BMJ case reports (24.05.2021)
Published in BMJ case reports (24.05.2021)
Get full text
Journal Article
Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas
Wo, Jennifer Y, Clark, Jeffrey W, Eyler, Christine E, Mino-Kenudson, Mari, Klempner, Samuel J, Allen, Jill N, Keane, Florence K, Parikh, Aparna R, Roeland, Eric, Drapek, Lorraine C, Ryan, David P, Corcoran, Ryan B, Van Seventer, Emily, Fetter, Isobel J, Shahzade, Heather A, Khandekar, Melin J, Lanuti, Michael, Morse, Christopher R, Heist, Rebecca S, Ulysse, Christine A, Christopher, Benjamin, Baglini, Christian, Yeap, Beow Y, Mullen, John T, Hong, Theodore S
Published in Clinical cancer research (01.12.2021)
Published in Clinical cancer research (01.12.2021)
Get full text
Journal Article
Pencil Beam Scanning Proton Beam Chemoradiation Therapy With 5-Fluorouracil and Mitomycin-C for Definitive Treatment of Carcinoma of the Anal Canal: A Multi-institutional Pilot Feasibility Study
Wo, Jennifer Y., Plastaras, John P., Metz, James M., Jiang, Wenqing, Yeap, Beow Y., Drapek, Lorraine C., Adams, Judith, Baglini, Christian, Ryan, David P., Murphy, Janet E., Parikh, Aparna R., Allen, Jill N., Clark, Jeffrey W., Blaszkowsky, Lawrence S., DeLaney, Thomas F., Ben-Josef, Edgar, Hong, Theodore S.
Published in International journal of radiation oncology, biology, physics (01.09.2019)
Published in International journal of radiation oncology, biology, physics (01.09.2019)
Get full text
Journal Article
Abstract A09: Therapeutic targeting of TSC2-deficient cells with Methotrexate: Results of a drug repurposing screen
Belaid, Amine, Filippakis, Harilaos, Lam, Hilaire, Valvezan, Alexander, Huang, Ruili, Xia, Menghang, Wen, Tianmu, Baglini, Christian, Sakamuru, Srilatha, Asara, John, Sinh, Nguyen Truong, Heard, Jeffrey J., Tamanoi, Fuyuhiko, Austin, Christopher, Manning, Brendan, Henske, Elizabeth P.
Published in Clinical cancer research (01.01.2017)
Published in Clinical cancer research (01.01.2017)
Get full text
Journal Article