Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)
Aik, WeiShen, Demetriades, Marina, Hamdan, Muhammad K. K, Bagg, Eleanor. A. L, Yeoh, Kar Kheng, Lejeune, Clarisse, Zhang, Zhihong, McDonough, Michael A, Schofield, Christopher J
Published in Journal of medicinal chemistry (09.05.2013)
Published in Journal of medicinal chemistry (09.05.2013)
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The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
Chowdhury, Rasheduzzaman, Yeoh, Kar Kheng, Tian, Ya-Min, Hillringhaus, Lars, Bagg, Eleanor A, Rose, Nathan R, Leung, Ivanhoe K H, Li, Xuan S, Woon, Esther C Y, Yang, Ming, McDonough, Michael A, King, Oliver N, Clifton, Ian J, Klose, Robert J, Claridge, Timothy D W, Ratcliffe, Peter J, Schofield, Christopher J, Kawamura, Akane
Published in EMBO reports (01.05.2011)
Published in EMBO reports (01.05.2011)
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A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene
Church, Chris, Lee, Sheena, Bagg, Eleanor A L, McTaggart, James S, Deacon, Robert, Gerken, Thomas, Lee, Angela, Moir, Lee, Mecinović, Jasmin, Quwailid, Mohamed M, Schofield, Christopher J, Ashcroft, Frances M, Cox, Roger D
Published in PLoS genetics (01.08.2009)
Published in PLoS genetics (01.08.2009)
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Emulsion PCR Significantly Improves Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures-Based Aptamer Selection: Allowing for Efficient and Rapid Selection of Aptamer to Unmodified ABH2 Protein
Yufa, Roman, Krylova, Svetlana M, Bruce, Christine, Bagg, Eleanor A, Schofield, Christopher J, Krylov, Sergey N
Published in Analytical chemistry (Washington) (20.01.2015)
Published in Analytical chemistry (Washington) (20.01.2015)
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5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation
Hopkinson, Richard J, Tumber, Anthony, Yapp, Clarence, Chowdhury, Rasheduzzaman, Aik, WeiShen, Che, Ka Hing, Li, Xuan Shirley, Kristensen, Jan B L, King, Oliver N F, Chan, Mun Chiang, Yeoh, Kar Kheng, Choi, Hwanho, Walport, Louise J, Thinnes, Cyrille C, Bush, Jacob T, Lejeune, Clarisse, Rydzik, Anna M, Rose, Nathan R, Bagg, Eleanor A, McDonough, Michael A, Krojer, Tobias, Yue, Wyatt W, Ng, Stanley S, Olsen, Lars, Brennan, Paul E, Oppermann, Udo, Muller-Knapp, Susanne, Klose, Robert J, Ratcliffe, Peter J, Schofield, Christopher J, Kawamura, Akane
Published in Chemical science (Cambridge) (01.08.2013)
Published in Chemical science (Cambridge) (01.08.2013)
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Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6
Mantri, Monica, Krojer, Tobias, Bagg, Eleanor A., Webby, Celia J., Butler, Danica S., Kochan, Grazyna, Kavanagh, Kathryn L., Oppermann, Udo, McDonough, Michael A., Schofield, Christopher J.
Published in Journal of molecular biology (13.08.2010)
Published in Journal of molecular biology (13.08.2010)
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Dynamic Combinatorial Mass Spectrometry Leads to Inhibitors of a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase
Woon, Esther C. Y, Demetriades, Marina, Bagg, Eleanor A. L, Aik, WeiShen, Krylova, Svetlana M, Ma, Jerome H. Y, Chan, MunChiang, Walport, Louise J, Wegman, David W, Dack, Kevin N, McDonough, Michael A, Krylov, Sergey N, Schofield, Christopher J
Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
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Specificity of localization and phosphotransfer in the CheA proteins of Rhodobacter sphaeroides
Scott, Kathryn A, Porter, Steven L, Bagg, Eleanor A.L, Hamer, Rebecca, Hill, Jennifer L, Wilkinson, David A, Armitage, Judith P
Published in Molecular microbiology (01.04.2010)
Published in Molecular microbiology (01.04.2010)
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Kinetic Rationale for Selectivity toward N- and C-terminal Oxygen-dependent Degradation Domain Substrates Mediated by a Loop Region of Hypoxia-Inducible Factor Prolyl Hydroxylases
Flashman, Emily, Bagg, Eleanor A.L., Chowdhury, Rasheduzzaman, Mecinović, Jasmin, Loenarz, Christoph, McDonough, Michael A., Hewitson, Kirsty S., Schofield, Christopher J.
Published in The Journal of biological chemistry (15.02.2008)
Published in The Journal of biological chemistry (15.02.2008)
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DNA aptamers for as analytical tools for the quantitative analysis of DNA-dealkylating enzymes
Krylova, Svetlana M., Karkhanina, Anna A., Musheev, Michael U., Bagg, Eleanor A.L., Schofield, Christopher J., Krylov, Sergey N.
Published in Analytical biochemistry (15.07.2011)
Published in Analytical biochemistry (15.07.2011)
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Performance evaluation of Sanger sequencing for the diagnosis of primary hyperoxaluria and comparison with targeted next generation sequencing
Williams, Emma L., Bagg, Eleanor A. L., Mueller, Michael, Vandrovcova, Jana, Aitman, Timothy J., Rumsby, Gill
Published in Molecular genetics & genomic medicine (01.01.2015)
Published in Molecular genetics & genomic medicine (01.01.2015)
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Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6
Mantri, Monica, Krojer, Tobias, Bagg, Eleanor A, Webby, Celia A, Butler, Danica S, Kochan, Grazyna, Kavanagh, Kathryn L, Oppermann, Udo, McDonough, Michael A, Schofield, Christopher J
Published in Journal of molecular biology (31.05.2010)
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Published in Journal of molecular biology (31.05.2010)
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A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene: e1000599
Church, Chris, Lee, Sheena, Bagg, Eleanor AL, McTaggart, James S, Deacon, Robert, Gerken, Thomas, Lee, Angela, Moir, Lee, Mecinovic, Jasmin, Quwailid, Mohamed M, Schofield, Christopher J, Ashcroft, Frances M, Cox, Roger D
Published in PLoS genetics (01.08.2009)
Published in PLoS genetics (01.08.2009)
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