Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease
Grand, Darren Le, Gosling, Martin, Baettig, Urs, Bahra, Parmjit, Bala, Kamlesh, Brocklehurst, Cara, Budd, Emma, Butler, Rebecca, Cheung, Atwood K, Choudhury, Hedaythul, Collingwood, Stephen P, Cox, Brian, Danahay, Henry, Edwards, Lee, Everatt, Brian, Glaenzel, Ulrike, Glotin, Anne-Lise, Groot-Kormelink, Paul, Hall, Edward, Hatto, Julia, Howsham, Catherine, Hughes, Glyn, King, Anna, Koehler, Julia, Kulkarni, Swarupa, Lightfoot, Megan, Nicholls, Ian, Page, Christopher, Pergl-Wilson, Giles, Popa, Mariana Oana, Robinson, Richard, Rowlands, David, Sharp, Tom, Spendiff, Matthew, Stanley, Emily, Steward, Oliver, Taylor, Roger J, Tranter, Pamela, Wagner, Trixie, Watson, Hazel, Williams, Gareth, Wright, Penny, Young, Alice, Sandham, David A
Published in Journal of medicinal chemistry (10.06.2021)
Published in Journal of medicinal chemistry (10.06.2021)
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Journal Article
Early Process Development of a Squaramide-Based CXCR2 Receptor Antagonist
Martin, Benjamin, Lai, Xinzhong, Baettig, Urs, Neumann, Eva, Kuhnle, Thomas, Porter, David, Robinson, Richard, Hatto, Julia, D’Souza, Anne-Marie, Steward, Oliver, Watson, Simon, Press, Neil J
Published in Organic process research & development (21.08.2015)
Published in Organic process research & development (21.08.2015)
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Journal Article
Design and synthesis of a library of chemokine antagonists
Bhalay, Gurdip, Albrecht, Birgit, Akhlaq, Mohammed, Baettig, Urs, Beer, David, Brown, Zarin, Charlton, Steven, Dunstan, Andrew, Bradley, Michelle, Gedeck, Peter, Glen, Angela, Howe, Trevor, Keller, Thomas, Leighton-Davies, Juliet, Li, Alice, McCarthy, Clive, Mocquet, Cecile, Owen, Charles, Nicklin, Paul, Rosethorne, Elizabeth
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
AUTOTAXIN INHIBITORS COMPRISING A HETEROAROMATIC RING-BENZYL-AMIDE-CYCLE CORE
STEWARD OLIVER ROSS, BAETTIG URS, PEARCE DAVID WILLIAM, SANDHAM DAVID ANDREW, LISTER ANDREW STUART, LEGRAND DARREN MARK, MCKENNA JEFFREY, BEATTIE DAVID, THOMSON CHRISTOPHER
Year of Publication 28.03.2016
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Year of Publication 28.03.2016
Patent
2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists
Sandham, David A., Aldcroft, Clive, Baettig, Urs, Barker, Lucy, Beer, David, Bhalay, Gurdip, Brown, Zarin, Dubois, Gerald, Budd, David, Bidlake, Louise, Campbell, Emma, Cox, Brian, Everatt, Brian, Harrison, David, Leblanc, Catherine J., Manini, Jodie, Profit, Rachael, Stringer, Rowan, Thompson, Katy S., Turner, Katharine L., Tweed, Morris F., Walker, Christoph, Watson, Simon J., Whitebread, Steven, Willis, Jennifer, Williams, Gareth, Wilson, Caroline
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
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Journal Article
PYRIDINE AND PYRAZINE DERIVATIVE FOR THE TREATMENT OF CF
BAETTIG URS, EDWARDS LEE, LEGRAND DARREN MARK, BUDD EMMA, SPIEGEL KATRIN, HUGHES GLYN, BALA KAMLESH JAGDIS, HOWSHAM CATHERINE
Year of Publication 25.01.2013
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Year of Publication 25.01.2013
Patent
ORGANIC COMPOUNDS
D'SOUZA ANNE MARIE, WATSON SIMON JAMES, BAETTIG URS, HUNT PETER, PRESS NEIL JOHN
Year of Publication 13.04.2011
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Year of Publication 13.04.2011
Patent
PYRIDINE DERIVATIVES
PULZ ROBERT ALEXANDER, BAETTIG URS, HUNT PETER, PIPET MAUDE NADINE PIERRETTE, ADCOCK CLAIRE, SPIEGEL KATRIN, STIEFL NIKOLAUS JOHANNES, LEBLANC CATHERINE
Year of Publication 16.09.2010
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Year of Publication 16.09.2010
Patent
Pyridine and pyrazine derivative for the treatment of chronic bronchitis
Howsham, Catherine, Baettig, Urs, Budd, Emma, Spiegel, Katrin, Bala, Kamlesh Jagdis, Edwards, Lee, Hughes, Glyn Alan, Le Grand, Darren Mark
Year of Publication 27.02.2024
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Year of Publication 27.02.2024
Patent
CHOLINE SALT OF AN ANTI - INFLAMMATORY SUBSTITUTED CYCLOBUTENEDIONE COMPOUND
AMBARKHANE, AMEET VIJAY, TIMPE, CARSTEN, BAETTIG, URS, MAULER, ARNAUD
Year of Publication 22.10.2019
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Year of Publication 22.10.2019
Patent
8-Aryl xanthines potent inhibitors of phosphodiesterase 5
Arnold, Ruth, Beer, David, Bhalay, Gurdip, Baettig, Urs, Collingwood, Stephen P, Craig, Sarah, Devereux, Nicholas, Dunstan, Andrew, Glen, Angela, Gomez, Sylvie, Haberthuer, Sandra, Howe, Trevor, Jelfs, Stephen, Moser, Heinz, Naef, Reto, Nicklin, Paul, Sandham, David, Stringer, Rowan, Turner, Katharine, Watson, Simon, Zurini, Mauro
Published in Bioorganic & medicinal chemistry letters (16.09.2002)
Published in Bioorganic & medicinal chemistry letters (16.09.2002)
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Journal Article
Choline salt of an anti-inflammatory substituted cyclobutenedione compound
Ambarkhane, Ameet Vijay, Baettig, Urs, Timpe, Carsten, Mauler, Arnaud
Year of Publication 24.01.2019
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Year of Publication 24.01.2019
Patent
CHOLINE SALT OF AN ANTI-INFLAMMATORY SUBSTITUTED CYCLOBUTENEDIONE COMPOUND
AMBARKHANE, Ameet Vijay, BAETTIG, Urs, TIMPE, Carsten, MAULER, Arnaud
Year of Publication 28.08.2018
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Year of Publication 28.08.2018
Patent
CHOLINE SALT OF AN ANTI-INFLAMMATORY SUBSTITUTED CYCLOBUTENEDIONE COMPOUND
AMBARKHANE, AMEET VIJAY, TIMPE, CARSTEN, BAETTIG, URS, MAULER, ARNAUD
Year of Publication 30.04.2018
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Year of Publication 30.04.2018
Patent
CHOLINE SALT OF AN ANTI-INFLAMMATORY SUBSTITUTED CYCLOBUTENEDIONE COMPOUND
AMBARKHANE, Ameet Vijay, BAETTIG, Urs, TIMPE, Carsten, MAULER, Arnaud
Year of Publication 28.02.2018
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Year of Publication 28.02.2018
Patent
Choline salt of an anti-inflammatory substituted cyclobutenedione compound
Ambarkhane, Ameet Vijay, Baettig, Urs, Timpe, Carsten, Mauler, Arnaud
Year of Publication 16.11.2017
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Year of Publication 16.11.2017
Patent