Heat activation is intrinsic to the pore domain of TRPV1
Zhang, Feng, Jara-Oseguera, Andres, Chang, Tsg-Hui, Bae, Chanhyung, Hanson, Sonya M., Swartz, Kenton J.
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2018)
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Journal Article
Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs
Matthies, Doreen, Bae, Chanhyung, Toombes, Gilman Es, Fox, Tara, Bartesaghi, Alberto, Subramaniam, Sriram, Swartz, Kenton Jon
Published in eLife (15.08.2018)
Published in eLife (15.08.2018)
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Journal Article
TRPM channels come into focus
Bae, Chanhyung, Jara-Oseguera, Andres, Swartz, Kenton J
Published in Science (American Association for the Advancement of Science) (12.01.2018)
Published in Science (American Association for the Advancement of Science) (12.01.2018)
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Journal Article
Cannabidiol sensitizes TRPV2 channels to activation by 2-APB
Gochman, Aaron, Tan, Xiao-Feng, Bae, Chanhyung, Chen, Helen, Swartz, Kenton J, Jara-Oseguera, Andres
Published in eLife (18.05.2023)
Published in eLife (18.05.2023)
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Journal Article
Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin
Bae, Chanhyung, Anselmi, Claudio, Kalia, Jeet, Jara-Oseguera, Andres, Schwieters, Charles D, Krepkiy, Dmitriy, Won Lee, Chul, Kim, Eun-Hee, Kim, Jae Il, Faraldo-Gómez, José D, Swartz, Kenton J
Published in eLife (10.02.2016)
Published in eLife (10.02.2016)
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Journal Article
Engineering vanilloid-sensitivity into the rat TRPV2 channel
Zhang, Feng, Hanson, Sonya M, Jara-Oseguera, Andres, Krepkiy, Dmitriy, Bae, Chanhyung, Pearce, Larry V, Blumberg, Peter M, Newstead, Simon, Swartz, Kenton J
Published in eLife (13.05.2016)
Published in eLife (13.05.2016)
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Journal Article
Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels
Gupta, Kanchan, Zamanian, Maryam, Bae, Chanhyung, Milescu, Mirela, Krepkiy, Dmitriy, Tilley, Drew C, Sack, Jon T, Yarov-Yarovoy, Vladimir, Kim, Jae Il, Swartz, Kenton J
Published in eLife (07.05.2015)
Published in eLife (07.05.2015)
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Journal Article
High yield production and refolding of the double-knot toxin, an activator of TRPV1 channels
Bae, Chanhyung, Kalia, Jeet, Song, Inhye, Yu, JeongHeon, Kim, Ha Hyung, Swartz, Kenton J, Kim, Jae Il
Published in PloS one (11.12.2012)
Published in PloS one (11.12.2012)
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Journal Article
Structural basis for regulation of Kv2.1 by PIP2
Tan, Xiaofeng, Fernández-Mariño, Ana I., Bae, Chanhyung, Swartz, Kenton
Published in Biophysical journal (08.02.2024)
Published in Biophysical journal (08.02.2024)
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Journal Article
Structures of the Kv2.1 channel and mechanism of inactivation through electromechanical coupling
Fernandez-Mariño, Ana, Tan, Xiaofeng, Bae, Chanhyung, Huffer, Kate, Jiang, Jiansen, Swartz, Kenton
Published in Biophysical journal (08.02.2024)
Published in Biophysical journal (08.02.2024)
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Journal Article
Cryo-EM structure of the mammalian Kv2.1 channel and epileptic encephalopathy mutations provide insight into electromechanical coupling and slow inactivation
Fernández-Mariño, Ana I., Tan, Xiaofeng, Bae, Chanhyung, Swartz, Kenton J.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
In vitro reconstitution of Wnt acylation reveals structural determinants of substrate recognition by the acyltransferase human Porcupine
Lee, Chul-Jin, Rana, Mitra S., Bae, Chanhyung, Li, Yan, Banerjee, Anirban
Published in The Journal of biological chemistry (04.01.2019)
Published in The Journal of biological chemistry (04.01.2019)
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Journal Article
Inactivation of the Kv2.1 channel through electromechanical coupling
Fernández-Mariño, Ana I., Tan, Xiao-Feng, Bae, Chanhyung, Huffer, Kate, Jiang, Jiansen, Swartz, Kenton J.
Published in Nature (London) (12.10.2023)
Published in Nature (London) (12.10.2023)
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Journal Article
Single-particle Cryo-EM of Membrane Proteins - Success Stories and Current Challenges
Matthies, Doreen, Qiu, Biao, Bae, Chanhyung, Perozo, Eduardo, Swartz, Kenton, Subramaniam, Sriram, Boudker, Olga, Yu, Zhiheng
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Structure of the shaker Kv channel and mechanism of slow C-type inactivation
Tan, Xiaofeng, Bae, Chanhyung, Stix, Robyn, Fernández-Mariño, Ana I., Huffer, Kate, Chang, Tsg-Hui, Jiang, Jiansen, Faraldo-Gómez, José D., Swartz, Kenton
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Cryo-EM structure of the mammalian Kv2.1 delayed-rectifier potassium channel reveals insight into gating mechanisms and epileptic encephalopathy
Fernández-Mariño, Ana I., Tan, Xiaofeng, Bae, Chanhyung, Stix, Robyn, Chang, Tsg-Hui, Jiang, Jiansen, Faraldo-Gómez, José D., Swartz, Kenton
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Extracellular Sodium is Required for Temperature-Dependent Gating in TRPV1 Channels
Jara-Oseguera, Andres, Bae, Chanhyung, Swartz, Kenton J.
Published in Biophysical journal (16.02.2016)
Published in Biophysical journal (16.02.2016)
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Journal Article
Structure of the Shaker Kv channel and mechanism of slow C-type inactivation
Tan, Xiao-Feng, Bae, Chanhyung, Stix, Robyn, Fernández-Mariño, Ana I, Huffer, Kate, Chang, Tsg-Hui, Jiang, Jiansen, Faraldo-Gómez, José D, Swartz, Kenton J
Published in Science advances (18.03.2022)
Published in Science advances (18.03.2022)
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Journal Article