Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma
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Published in Journal of medicinal chemistry (09.07.2020)
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A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation
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Published in PloS one (12.01.2016)
Published in PloS one (12.01.2016)
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A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
Matyskiela, Mary E, Zhang, Weihong, Man, Hon-Wah, Muller, George, Khambatta, Godrej, Baculi, Frans, Hickman, Matthew, LeBrun, Laurie, Pagarigan, Barbra, Carmel, Gilles, Lu, Chin-Chun, Lu, Gang, Riley, Mariko, Satoh, Yoshitaka, Schafer, Peter, Daniel, Thomas O, Carmichael, James, Cathers, Brian E, Chamberlain, Philip P
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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Protein Degradation via CRL4(CRBN) Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Hansen, Joshua D., Condroski, Kevin, Correa, Matthew, Muller, George, Man, Hon-Wah, Ruchelman, Alexander, Zhang, Weihong, Vocanson, Fan, Crea, Tim, Liu, Wei, Lu, Gang, Baculi, Frans, LeBrun, Laurie, Mahmoudi, Afshin, Carmel, Gilles, Hickman, Matt, Lu, Chin-Chun
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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Journal Article
Protein Degradation via CRL4 CRBN Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Hansen, Joshua D, Condroski, Kevin, Correa, Matthew, Muller, George, Man, Hon-Wah, Ruchelman, Alexander, Zhang, Weihong, Vocanson, Fan, Crea, Tim, Liu, Wei, Lu, Gang, Baculi, Frans, LeBrun, Laurie, Mahmoudi, Afshin, Carmel, Gilles, Hickman, Matt, Lu, Chin-Chun
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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Journal Article
Protein Degradation via CRL4CRBN Ubiquitin Ligase: Discovery and Structure–Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Hansen, Joshua D, Condroski, Kevin, Correa, Matthew, Muller, George, Man, Hon-Wah, Ruchelman, Alexander, Zhang, Weihong, Vocanson, Fan, Crea, Tim, Liu, Wei, Lu, Gang, Baculi, Frans, LeBrun, Laurie, Mahmoudi, Afshin, Carmel, Gilles, Hickman, Matt, Lu, Chin-Chun
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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Year of Publication 08.02.2022
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Year of Publication 08.02.2022
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SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
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Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith
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Year of Publication 19.04.2022
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SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
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Year of Publication 04.01.2023
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COMPUESTOS DE 1-OXO-ISOINDOLIN-5-CARBOXAMIDA SUSTITUIDA, COMPOSICIONES DE ESTOS Y METODOS DE TRATAMIENTO CON DICHOS COMPUESTOS
LEBRUN, Laurie A, LU, Chin-Chun, PENG, Sophie, CORREA, Matthew D, NAGY, Mark A, NORTHCOTE, Katherine, HANSEN, Joshua, LU, Gang, PERRIN-NINKOVIC, Sophie, BACULI, Frans
Year of Publication 20.04.2022
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Year of Publication 20.04.2022
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SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
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Year of Publication 06.04.2022
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Year of Publication 06.04.2022
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Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith
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Year of Publication 01.01.2022
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SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
LEBRUN, Laurie A, LU, Chin-Chun, PENG, Sophie, CORREA, Matthew D, NAGY, Mark A, NORTHCOTE, Katherine, HANSEN, Joshua, LU, Gang, PERRIN-NINKOVIC, Sophie, BACULI, Frans
Year of Publication 30.12.2021
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Year of Publication 30.12.2021
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Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith
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Year of Publication 09.12.2021
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Year of Publication 09.12.2021
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SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
Perrin-Ninkovic, Sophie, Hansen, Joshua, Baculi, Frans, Peng, Sophie, Lu, Chin-Chun, Correa, Matthew D, Lu, Gang, Lebrun, Laurie A, Nagy, Mark A, Northcote, Katherine
Year of Publication 03.12.2020
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Year of Publication 03.12.2020
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SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
NAGY, MARK A, HANSEN, JOSHUA, PERRIN-NINKOVIC, SOPHIE, LEBRUN, LAURIE A, LU, CHINUN, NORTHCOTE, KATHERINE, BACULI, FRANS, PENG, SOPHIE, CORREA, MATTHEW D, LU, GANG
Year of Publication 03.12.2020
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Year of Publication 03.12.2020
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SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
LEBRUN, Laurie A, LU, Chin-Chun, PENG, Sophie, CORREA, Matthew D, NAGY, Mark A, NORTHCOTE, Katherine, HANSEN, Joshua, LU, Gang, PERRIN-NINKOVIC, Sophie, BACULI, Frans
Year of Publication 03.12.2020
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Inhibition of metalloproteinase by futoenone derivatives
Yeh, Li-An, Chen, James, Baculi, Frans, Gingrich, Diane E., Shen, T.Y.
Published in Bioorganic & medicinal chemistry letters (03.08.1995)
Published in Bioorganic & medicinal chemistry letters (03.08.1995)
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Compostos de 1-oxo-isoindolina-5-carboxamida substituídos, suas composições e métodos de tratamento com os mesmos
HANSEN JOSHUA, PERRIN-NINKOVIC SOPHIE, MARK A. NAGY, NORTHCOTE KATHERINE, MATTHEW D. CORREA, PENG SOPHIE, LU CHINUN, LU GANG, BACULI FRANS, LAURIE A. LEBRUN
Year of Publication 22.03.2022
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Year of Publication 22.03.2022
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