Calcium Signaling and Transcriptional Regulation in Cardiomyocytes
Dewenter, Matthias, von der Lieth, Albert, Katus, Hugo A, Backs, Johannes
Published in Circulation research (29.09.2017)
Published in Circulation research (29.09.2017)
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Physiological and unappreciated roles of CaMKII in the heart
Beckendorf, Jan, van den Hoogenhof, Maarten M. G., Backs, Johannes
Published in Basic research in cardiology (01.07.2018)
Published in Basic research in cardiology (01.07.2018)
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Journal Article
O-GlcNAcylation of Histone Deacetylase 4 Protects the Diabetic Heart From Failure
Kronlage, Mariya, Dewenter, Matthias, Grosso, Johannes, Fleming, Thomas, Oehl, Ulrike, Lehmann, Lorenz H, Falcão-Pires, Inês, Leite-Moreira, Adelino F, Volk, Nadine, Gröne, Hermann-Josef, Müller, Oliver J, Sickmann, Albert, Katus, Hugo A, Backs, Johannes
Published in Circulation (New York, N.Y.) (13.08.2019)
Published in Circulation (New York, N.Y.) (13.08.2019)
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Journal Article
Stroke–Heart Syndrome: Recent Advances and Challenges
Scheitz, Jan F., Sposato, Luciano A., Schulz‐Menger, Jeanette, Nolte, Christian H., Backs, Johannes, Endres, Matthias
Published in Journal of the American Heart Association (06.09.2022)
Published in Journal of the American Heart Association (06.09.2022)
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Journal Article
Secretome Analysis of Cardiomyocytes Identifies PCSK6 (Proprotein Convertase Subtilisin/Kexin Type 6) as a Novel Player in Cardiac Remodeling After Myocardial Infarction
Kuhn, Tim Christian, Knobel, Johannes, Burkert-Rettenmaier, Sonja, Li, Xue, Meyer, Ingmar Sören, Jungmann, Andreas, Sicklinger, Florian, Backs, Johannes, Lasitschka, Felix, Müller, Oliver J., Katus, Hugo A., Krijgsveld, Jeroen, Leuschner, Florian
Published in Circulation (New York, N.Y.) (19.05.2020)
Published in Circulation (New York, N.Y.) (19.05.2020)
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Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart
Jabs, Markus, Rose, Adam J, Lehmann, Lorenz H, Taylor, Jacqueline, Moll, Iris, Sijmonsma, Tjeerd P, Herberich, Stefanie E, Sauer, Sven W, Poschet, Gernot, Federico, Giuseppina, Mogler, Carolin, Weis, Eva-Maria, Augustin, Hellmut G, Yan, Minhong, Gretz, Norbert, Schmid, Roland M, Adams, Ralf H, Gröne, Hermann-Joseph, Hell, Rüdiger, Okun, Jürgen G, Backs, Johannes, Nawroth, Peter P, Herzig, Stephan, Fischer, Andreas
Published in Circulation (New York, N.Y.) (12.06.2018)
Published in Circulation (New York, N.Y.) (12.06.2018)
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Journal Article
RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling
van den Hoogenhof, Maarten M.G, Beqqali, Abdelaziz, Amin, Ahmad S, van der Made, Ingeborg, Aufiero, Simona, Khan, Mohsin A.F, Schumacher, Cees A, Jansweijer, Joeri A, van Spaendonck-Zwarts, Karin Y, Remme, Carol Ann, Backs, Johannes, Verkerk, Arie O, Baartscheer, Antonius, Pinto, Yigal M, Creemers, Esther E
Published in Circulation (New York, N.Y.) (25.09.2018)
Published in Circulation (New York, N.Y.) (25.09.2018)
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Journal Article
Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure
Meder, Benjamin, Haas, Jan, Sedaghat-Hamedani, Farbod, Kayvanpour, Elham, Frese, Karen, Lai, Alan, Nietsch, Rouven, Scheiner, Christina, Mester, Stefan, Bordalo, Diana Martins, Amr, Ali, Dietrich, Carsten, Pils, Dietmar, Siede, Dominik, Hund, Hauke, Bauer, Andrea, Holzer, Daniel Benjamin, Ruhparwar, Arjang, Mueller-Hennessen, Matthias, Weichenhan, Dieter, Plass, Christoph, Weis, Tanja, Backs, Johannes, Wuerstle, Maximilian, Keller, Andreas, Katus, Hugo A, Posch, Andreas E
Published in Circulation (New York, N.Y.) (17.10.2017)
Published in Circulation (New York, N.Y.) (17.10.2017)
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Journal Article
Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function
Wang, Yinuo, Elsherbiny, Adel, Kessler, Linda, Cordero, Julio, Shi, Haojie, Serke, Heike, Lityagina, Olga, Trogisch, Felix A., Mohammadi, Mona Malek, El-Battrawy, Ibrahim, Backs, Johannes, Wieland, Thomas, Heineke, Joerg, Dobreva, Gergana
Published in Nature communications (04.11.2022)
Published in Nature communications (04.11.2022)
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Journal Article
Crucial Role for Ca2+/Calmodulin-Dependent Protein Kinase-II in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation
Hamdani, Nazha, Krysiak, Judith, Kreusser, Michael M, Neef, Stefan, dos Remedios, Cristobal G, Maier, Lars S, Krüger, Markus, Backs, Johannes, Linke, Wolfgang A
Published in Circulation research (15.02.2013)
Published in Circulation research (15.02.2013)
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Journal Article
Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases
Moresi, Viviana, Williams, Andrew H., Meadows, Eric, Flynn, Jesse M., Potthoff, Matthew J., McAnally, John, Shelton, John M., Backs, Johannes, Klein, William H., Richardson, James A., Bassel-Duby, Rhonda, Olson, Eric N.
Published in Cell (01.10.2010)
Published in Cell (01.10.2010)
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Journal Article
HDAC4 controls histone methylation in response to elevated cardiac load
Hohl, Mathias, Wagner, Michael, Reil, Jan-Christian, Müller, Sarah-Anne, Tauchnitz, Marcus, Zimmer, Angela M, Lehmann, Lorenz H, Thiel, Gerald, Böhm, Michael, Backs, Johannes, Maack, Christoph
Published in The Journal of clinical investigation (01.03.2013)
Published in The Journal of clinical investigation (01.03.2013)
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Journal Article
Ketone body oxidation increases cardiac endothelial cell proliferation
Weis, Eva‐Maria, Puchalska, Patrycja, Nelson, Alisa B, Taylor, Jacqueline, Moll, Iris, Hasan, Sana S, Dewenter, Matthias, Hagenmüller, Marco, Fleming, Thomas, Poschet, Gernot, Hotz‐Wagenblatt, Agnes, Backs, Johannes, Crawford, Peter A, Fischer, Andreas
Published in EMBO molecular medicine (07.04.2022)
Published in EMBO molecular medicine (07.04.2022)
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Journal Article
Adaptive versus maladaptive cardiac remodelling in response to sustained β-adrenergic stimulation in a new 'ISO on/off model'
Werhahn, Stefanie Maria, Kreusser, Julia S, Hagenmüller, Marco, Beckendorf, Jan, Diemert, Nathalie, Hoffmann, Sophia, Schultz, Jobst-Hendrik, Backs, Johannes, Dewenter, Matthias
Published in PloS one (17.06.2021)
Published in PloS one (17.06.2021)
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Journal Article
Calcium Signaling through CaMKII Regulates Hepatic Glucose Production in Fasting and Obesity
Ozcan, Lale, Wong, Catherine C.L., Li, Gang, Xu, Tao, Pajvani, Utpal, Park, Sung Kyu Robin, Wronska, Anetta, Chen, Bi-Xing, Marks, Andrew R., Fukamizu, Akiyoshi, Backs, Johannes, Singer, Harold A., Yates, John R., Accili, Domenico, Tabas, Ira
Published in Cell metabolism (02.05.2012)
Published in Cell metabolism (02.05.2012)
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Journal Article
δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload
Backs, Johannes, Backs, Thea, Neef, Stefan, Kreusser, Michael M, Lehmann, Lorenz H, Patrick, David M, Grueter, Chad E, Qi, Xiaoxia, Richardson, James A, Hill, Joseph A, Katus, Hugo A, Bassel-Duby, Rhonda, Maier, Lars S, Olson, Eric N
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
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Journal Article
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy
Grosch, Markus, Schraft, Laura, Chan, Adrian, Küchenhoff, Leonie, Rapti, Kleopatra, Ferreira, Anne-Maud, Kornienko, Julia, Li, Shengdi, Radke, Michael H., Krämer, Chiara, Clauder-Münster, Sandra, Perlas, Emerald, Backs, Johannes, Gotthardt, Michael, Dieterich, Christoph, van den Hoogenhof, Maarten M. G., Grimm, Dirk, Steinmetz, Lars M.
Published in Nature communications (22.06.2023)
Published in Nature communications (22.06.2023)
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