Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions
Backman, Janne T, Filppula, Anne M, Niemi, Mikko, Neuvonen, Pertti J
Published in Pharmacological reviews (01.01.2016)
Published in Pharmacological reviews (01.01.2016)
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Journal Article
VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection
Räsänen, Markus, Degerman, Joni, Nissinen, Tuuli A., Miinalainen, Ilkka, Kerkelä, Risto, Siltanen, Antti, Backman, Janne T., Mervaala, Eero, Hulmi, Juha J., Kivelä, Riikka, Alitalo, Kari
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2016)
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Journal Article
Enantiospecific Pharmacogenomics of Fluvastatin
Hirvensalo, Päivi, Tornio, Aleksi, Neuvonen, Mikko, Kiander, Wilma, Kidron, Heidi, Paile‐Hyvärinen, Maria, Tapaninen, Tuija, Backman, Janne T., Niemi, Mikko
Published in Clinical pharmacology and therapeutics (01.09.2019)
Published in Clinical pharmacology and therapeutics (01.09.2019)
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Journal Article
Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review
Kuula, Laura S M, Viljemaa, Kati M, Backman, Janne T, Blom, Marja
Published in PloS one (26.04.2019)
Published in PloS one (26.04.2019)
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Journal Article
Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans
Itkonen, Matti K, Tornio, Aleksi, Neuvonen, Mikko, Neuvonen, Pertti J, Niemi, Mikko, Backman, Janne T
Published in Drug metabolism and disposition (01.04.2019)
Published in Drug metabolism and disposition (01.04.2019)
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Journal Article
Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters
Tornio, Aleksi, Neuvonen, Pertti J, Niemi, Mikko, Backman, Janne T
Published in Expert opinion on drug metabolism & toxicology (02.01.2017)
Published in Expert opinion on drug metabolism & toxicology (02.01.2017)
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Journal Article
Simvastatin Decreases Lipopolysaccharide-induced Pulmonary Inflammation in Healthy Volunteers
Shyamsundar, Murali, McKeown, Scott T. W, O'Kane, Cecilia M, Craig, Thelma R, Brown, Vanessa, Thickett, David R, Matthay, Michael A, Taggart, Clifford C, Backman, Janne T, Elborn, J. Stuart, McAuley, Daniel F
Published in American journal of respiratory and critical care medicine (15.06.2009)
Published in American journal of respiratory and critical care medicine (15.06.2009)
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Journal Article
Non‐targeted metabolomics for the identification of plasma metabolites associated with organic anion transporting polypeptide 1B1 function
Hämäläinen, Kreetta, Hirvensalo, Päivi, Neuvonen, Mikko, Tornio, Aleksi, Backman, Janne T., Lehtonen, Marko, Niemi, Mikko
Published in Clinical and translational science (01.03.2024)
Published in Clinical and translational science (01.03.2024)
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Journal Article
Autoinhibition of CYP3A4 leads to important role of CYP2C8 in imatinib metabolism: variability in CYP2C8 activity may alter plasma concentrations and response
Filppula, Anne M, Neuvonen, Mikko, Laitila, Jouko, Neuvonen, Pertti J, Backman, Janne T
Published in Drug metabolism and disposition (01.01.2013)
Published in Drug metabolism and disposition (01.01.2013)
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Journal Article
Prevention of chemotherapy‐induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle
Hulmi, Juha J., Nissinen, Tuuli A., Räsänen, Markus, Degerman, Joni, Lautaoja, Juulia H., Hemanthakumar, Karthik Amudhala, Backman, Janne T., Ritvos, Olli, Silvennoinen, Mika, Kivelä, Riikka
Published in Journal of cachexia, sarcopenia and muscle (01.04.2018)
Published in Journal of cachexia, sarcopenia and muscle (01.04.2018)
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Journal Article
Itraconazole Increases Ibrutinib Exposure 10‐Fold and Reduces Interindividual Variation—A Potentially Beneficial Drug‐Drug Interaction
Tapaninen, Tuija, Olkkola, Aleksi M., Tornio, Aleksi, Neuvonen, Mikko, Elonen, Erkki, Neuvonen, Pertti J., Niemi, Mikko, Backman, Janne T.
Published in Clinical and translational science (01.03.2020)
Published in Clinical and translational science (01.03.2020)
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Journal Article
Simvastatin pre-treatment improves survival and mitochondrial function in a 3-day fluid-resuscitated rat model of sepsis
Morel, Jerome, Hargreaves, Iain, Brealey, David, Neergheen, Viruna, Backman, Janne T, Lindig, Sandro, Bläss, Marcus, Bauer, Michael, McAuley, Daniel F, Singer, Mervyn
Published in Clinical science (1979) (25.04.2017)
Published in Clinical science (1979) (25.04.2017)
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Journal Article
The effect of hydroxychloroquine on cholesterol synthesis depends on the profile of cholesterol metabolism. A controlled clinical study
Simonen, Piia, Ulander, Lotta, Eklund, Kari K., Niemi, Mikko, Backman, Janne T., Gylling, Helena, Sinisalo, Juha
Published in Atherosclerosis plus (01.03.2024)
Published in Atherosclerosis plus (01.03.2024)
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Journal Article
Pharmacogenomics of celiprolol – evidence for a role of P‐glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics
Hirvensalo, Päivi, Tornio, Aleksi, Tapaninen, Tuija, Paile‐Hyvärinen, Maria, Neuvonen, Mikko, Backman, Janne T., Niemi, Mikko
Published in Clinical and translational science (01.02.2022)
Published in Clinical and translational science (01.02.2022)
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