Macropinocytosis: mechanisms and regulation
Salloum, Gilbert, Bresnick, Anne R, Backer, Jonathan M
Published in Biochemical journal (15.03.2023)
Published in Biochemical journal (15.03.2023)
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Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
Wang, Qing Jun, Li, Xianting, Yan, Ying, Yue, Zhenyu, Chait, Brian T, Zhong, Yun, Heintz, Nathaniel, Backer, Jonathan M
Published in Nature cell biology (01.04.2009)
Published in Nature cell biology (01.04.2009)
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Class IA PI3K p110β Subunit Promotes Autophagy through Rab5 Small GTPase in Response to Growth Factor Limitation
Dou, Zhixun, Pan, Ji-An, Dbouk, Hashem A., Ballou, Lisa M., DeLeon, Jennifer L., Fan, Yongjun, Chen, Juei-Suei, Liang, Zhimin, Li, Guangpu, Backer, Jonathan M., Lin, Richard Z., Zong, Wei-Xing
Published in Molecular cell (11.04.2013)
Published in Molecular cell (11.04.2013)
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NRBF2 regulates macroautophagy as a component of Vps34 Complex I
Cao, Yanyan, Wang, Yichen, Abi Saab, Widian F, Yang, Fajun, Pessin, Jeffrey E, Backer, Jonathan M
Published in Biochemical journal (15.07.2014)
Published in Biochemical journal (15.07.2014)
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PI3Kβ links integrin activation and PI(3,4)P2 production during invadopodial maturation
Erami, Zahra, Heitz, Samantha, Bresnick, Anne R, Backer, Jonathan M
Published in Molecular biology of the cell (15.08.2019)
Published in Molecular biology of the cell (15.08.2019)
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Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway
Yoon, Mee-Sup, Du, Guangwei, Backer, Jonathan M, Frohman, Michael A, Chen, Jie
Published in The Journal of cell biology (31.10.2011)
Published in The Journal of cell biology (31.10.2011)
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PI3Kβ links integrin activation and PI(3,4)P 2 production during invadopodial maturation
Erami, Zahra, Heitz, Samantha, Bresnick, Anne R, Backer, Jonathan M
Published in Molecular biology of the cell (15.08.2019)
Published in Molecular biology of the cell (15.08.2019)
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hVps34 Is a Nutrient-regulated Lipid Kinase Required for Activation of p70 S6 Kinase
Byfield, Maya P., Murray, James T., Backer, Jonathan M.
Published in The Journal of biological chemistry (23.09.2005)
Published in The Journal of biological chemistry (23.09.2005)
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PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
Braccini, Laura, Ciraolo, Elisa, Campa, Carlo C., Perino, Alessia, Longo, Dario L., Tibolla, Gianpaolo, Pregnolato, Marco, Cao, Yanyan, Tassone, Beatrice, Damilano, Federico, Laffargue, Muriel, Calautti, Enzo, Falasca, Marco, Norata, Giuseppe D., Backer, Jonathan M., Hirsch, Emilio
Published in Nature communications (23.06.2015)
Published in Nature communications (23.06.2015)
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Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity
Alliouachene, Samira, Bilanges, Benoit, Chicanne, Gaëtan, Anderson, Karen E., Pearce, Wayne, Ali, Khaled, Valet, Colin, Posor, York, Low, Pei Ching, Chaussade, Claire, Scudamore, Cheryl L., Salamon, Rachel S., Backer, Jonathan M., Stephens, Len, Hawkins, Phill T., Payrastre, Bernard, Vanhaesebroeck, Bart
Published in Cell reports (Cambridge) (01.12.2015)
Published in Cell reports (Cambridge) (01.12.2015)
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PI3Kβ is selectively required for growth factor-stimulated macropinocytosis
Salloum, Gilbert, Jakubik, Charles T, Erami, Zahra, Heitz, Samantha D, Bresnick, Anne R, Backer, Jonathan M
Published in Journal of cell science (16.08.2019)
Published in Journal of cell science (16.08.2019)
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Mechanism of Two Classes of Cancer Mutations in the Phosphoinositide 3-Kinase Catalytic Subunit
Miled, Nabil, Yan, Ying, Hon, Wai-Ching, Perisic, Olga, Zvelebil, Marketa, Inbar, Yuval, Schneidman-Duhovny, Dina, Wolfson, Haim J., Backer, Jonathan M., Williams, Roger L.
Published in Science (American Association for the Advancement of Science) (13.07.2007)
Published in Science (American Association for the Advancement of Science) (13.07.2007)
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The late endosome is essential for mTORC1 signaling
Flinn, Rory J, Yan, Ying, Goswami, Sumanta, Parker, Peter J, Backer, Jonathan M
Published in Molecular biology of the cell (01.03.2010)
Published in Molecular biology of the cell (01.03.2010)
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Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism
Bilanges, Benoit, Alliouachene, Samira, Pearce, Wayne, Morelli, Daniele, Szabadkai, Gyorgy, Chung, Yuen-Li, Chicanne, Gaëtan, Valet, Colin, Hill, Julia M., Voshol, Peter J., Collinson, Lucy, Peddie, Christopher, Ali, Khaled, Ghazaly, Essam, Rajeeve, Vinothini, Trichas, Georgios, Srinivas, Shankar, Chaussade, Claire, Salamon, Rachel S., Backer, Jonathan M., Scudamore, Cheryl L., Whitehead, Maria A., Keaney, Erin P., Murphy, Leon O., Semple, Robert K., Payrastre, Bernard, Tooze, Sharon A., Vanhaesebroeck, Bart
Published in Nature communications (27.11.2017)
Published in Nature communications (27.11.2017)
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