Post-translational modifications of Hsp90 and translating the chaperone code
Backe, Sarah J., Sager, Rebecca A., Woodford, Mark R., Makedon, Alan M., Mollapour, Mehdi
Published in The Journal of biological chemistry (07.08.2020)
Published in The Journal of biological chemistry (07.08.2020)
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Journal Article
PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling
Backe, Sarah J., Votra, SarahBeth D., Stokes, Matthew P., Sebestyén, Endre, Castelli, Matteo, Torielli, Luca, Colombo, Giorgio, Woodford, Mark R., Mollapour, Mehdi, Bourboulia, Dimitra
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Journal Article
TRAP1 Chaperones the Metabolic Switch in Cancer
Wengert, Laura A., Backe, Sarah J., Bourboulia, Dimitra, Mollapour, Mehdi, Woodford, Mark R.
Published in Biomolecules (Basel, Switzerland) (04.06.2022)
Published in Biomolecules (Basel, Switzerland) (04.06.2022)
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Journal Article
Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
Backe, Sarah J., Sager, Rebecca A., Heritz, Jennifer A., Wengert, Laura A., Meluni, Katherine A., Aran-Guiu, Xavier, Panaretou, Barry, Woodford, Mark R., Prodromou, Chrisostomos, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (25.07.2023)
Published in Cell reports (Cambridge) (25.07.2023)
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Journal Article
Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90
Sager, Rebecca A., Woodford, Mark R., Backe, Sarah J., Makedon, Alan M., Baker-Williams, Alexander J., DiGregorio, Bryanna T., Loiselle, David R., Haystead, Timothy A., Zachara, Natasha E., Prodromou, Chrisostomos, Bourboulia, Dimitra, Schmidt, Laura S., Linehan, W. Marston, Bratslavsky, Gennady, Mollapour, Mehdi
Published in Cell reports (Cambridge) (29.01.2019)
Published in Cell reports (Cambridge) (29.01.2019)
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Journal Article
Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
Backe, Sarah J., Sager, Rebecca A., Heritz, Jennifer A., Wengert, Laura A., Meluni, Katherine A., Aran-Guiu, Xavier, Panaretou, Barry, Woodford, Mark R., Prodromou, Chrisostomos, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
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Journal Article
Targeting extracellular Hsp90: A unique frontier against cancer
Sager, Rebecca A., Khan, Farzana, Toneatto, Lorenzo, Votra, SarahBeth D., Backe, Sarah J., Woodford, Mark R., Mollapour, Mehdi, Bourboulia, Dimitra
Published in Frontiers in molecular biosciences (17.08.2022)
Published in Frontiers in molecular biosciences (17.08.2022)
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Journal Article
Flow cytometry FRET reveals post-translational modifications drive Protein Phosphatase-5 conformational changes in mammalian cells
Sager, Rebecca A., Backe, Sarah J., Heritz, Jennifer, Woodford, Mark R., Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell stress & chaperones (10.10.2024)
Published in Cell stress & chaperones (10.10.2024)
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Journal Article
A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand
Backe, Sarah J., Sager, Rebecca A., Regan, Bethany R., Sit, Julian, Major, Lauren A., Bratslavsky, Gennady, Woodford, Mark R., Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (12.07.2022)
Published in Cell reports (Cambridge) (12.07.2022)
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Journal Article
Structural and functional regulation of lactate dehydrogenase-A in cancer
Woodford, Mark R, Chen, Victor Z, Backe, Sarah J, Bratslavsky, Gennady, Mollapour, Mehdi
Published in Future medicinal chemistry (01.03.2020)
Published in Future medicinal chemistry (01.03.2020)
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Journal Article
SUMOylation of protein phosphatase 5 regulates phosphatase activity and substrate release
Sager, Rebecca A, Backe, Sarah J, Dunn, Diana M, Heritz, Jennifer A, Ahanin, Elham, Dushukyan, Natela, Panaretou, Barry, Bratslavsky, Gennady, Woodford, Mark R, Bourboulia, Dimitra, Mollapour, Mehdi
Published in EMBO reports (20.09.2024)
Published in EMBO reports (20.09.2024)
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Journal Article
Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90–Client Interactions
Paladino, Antonella, Woodford, Mark R., Backe, Sarah J., Sager, Rebecca A., Kancherla, Priyanka, Daneshvar, Michael A., Chen, Victor Z., Bourboulia, Dimitra, Ahanin, Elham F., Prodromou, Chrisostomos, Bergamaschi, Greta, Strada, Alessandro, Cretich, Marina, Gori, Alessandro, Veronesi, Marina, Bandiera, Tiziano, Vanna, Renzo, Bratslavsky, Gennady, Serapian, Stefano A., Mollapour, Mehdi, Colombo, Giorgio
Published in Chemistry : a European journal (03.08.2020)
Published in Chemistry : a European journal (03.08.2020)
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Journal Article
Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer
Ahanin, Elham F., Sager, Rebecca A., Backe, Sarah J., Dunn, Diana M., Dushukyan, Natela, Blanden, Adam R., Mate, Nilamber A., Suzuki, Tamie, Anderson, Tyler, Roy, Merin, Oberoi, Jasmeen, Prodromou, Chrisostomos, Nsouli, Imad, Daneshvar, Michael, Bratslavsky, Gennady, Woodford, Mark R., Bourboulia, Dimitra, Chisholm, John D., Mollapour, Mehdi
Published in Cell chemical biology (19.10.2023)
Published in Cell chemical biology (19.10.2023)
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Journal Article