Structural basis for selectivity and diversity in angiotensin II receptors
Zhang, Haitao, Han, Gye Won, Batyuk, Alexander, Ishchenko, Andrii, White, Kate L., Patel, Nilkanth, Sadybekov, Anastasiia, Zamlynny, Beata, Rudd, Michael T., Hollenstein, Kaspar, Tolstikova, Alexandra, White, Thomas A., Hunter, Mark S., Weierstall, Uwe, Liu, Wei, Babaoglu, Kerim, Moore, Eric L., Katz, Ryan D., Shipman, Jennifer M., Garcia-Calvo, Margarita, Sharma, Sujata, Sheth, Payal, Soisson, Stephen M., Stevens, Raymond C., Katritch, Vsevolod, Cherezov, Vadim
Published in Nature (London) (20.04.2017)
Published in Nature (London) (20.04.2017)
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Journal Article
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors
Yin, Jie, Babaoglu, Kerim, Brautigam, Chad A, Clark, Lindsay, Shao, Zhenhua, Scheuermann, Thomas H, Harrell, Charles M, Gotter, Anthony L, Roecker, Anthony J, Winrow, Christopher J, Renger, John J, Coleman, Paul J, Rosenbaum, Daniel M
Published in Nature structural & molecular biology (01.04.2016)
Published in Nature structural & molecular biology (01.04.2016)
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Journal Article
Validation of Molecular Docking Programs for Virtual Screening against Dihydropteroate Synthase
Hevener, Kirk E, Zhao, Wei, Ball, David M, Babaoglu, Kerim, Qi, Jianjun, White, Stephen W, Lee, Richard E
Published in Journal of Chemical Information and Modeling (23.02.2009)
Published in Journal of Chemical Information and Modeling (23.02.2009)
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Journal Article
Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study
Mackman, Richard L, Sangi, Michael, Sperandio, David, Parrish, Jay P, Eisenberg, Eugene, Perron, Michel, Hui, Hon, Zhang, Lijun, Siegel, Dustin, Yang, Hai, Saunders, Oliver, Boojamra, Constantine, Lee, Gary, Samuel, Dharmaraj, Babaoglu, Kerim, Carey, Anne, Gilbert, Brian E, Piedra, Pedro A, Strickley, Robert, Iwata, Quynh, Hayes, Jaclyn, Stray, Kirsten, Kinkade, April, Theodore, Dorothy, Jordan, Robert, Desai, Manoj, Cihlar, Tomas
Published in Journal of medicinal chemistry (26.02.2015)
Published in Journal of medicinal chemistry (26.02.2015)
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Journal Article
The HIV-1 reverse transcriptase M184I mutation enhances the E138K-associated resistance to rilpivirine and decreases viral fitness
Kulkarni, Rima, Babaoglu, Kerim, Lansdon, Eric B, Rimsky, Laurence, Van Eygen, Veerle, Picchio, Gaston, Svarovskaia, Evguenia, Miller, Michael D, White, Kirsten L
Published in Journal of acquired immune deficiency syndromes (1999) (01.01.2012)
Published in Journal of acquired immune deficiency syndromes (1999) (01.01.2012)
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Journal Article
A Small-Molecule Inhibitor of Hepatitis C Virus Infectivity
BUSH, Caroline O, POKROVSKII, Maria V, PAGRATIS, Nikos, WEIDONG ZHONG, DELANEY, William E, PAULSON, Matthew S, BERAN, Rudolf K. F, SAITO, Roland, MORGANELLI, Philip, CANALES, Eda, CLARKE, Michael O, LAZERWITH, Scott E, GOLDE, Justin, REID, Brian G, BABAOGLU, Kerim
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
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Journal Article
Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis
Babaoglu, Kerim, Page, Mark A., Jones, Victoria C., McNeil, Michael R., Dong, Changjiang, Naismith, James H., Lee, Richard E.
Published in Bioorganic & medicinal chemistry letters (06.10.2003)
Published in Bioorganic & medicinal chemistry letters (06.10.2003)
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Journal Article
Affinities between the Binding Partners of the HIV-1 Integrase Dimer-Lens Epithelium-derived Growth Factor (IN Dimer-LEDGF) Complex
Tsiang, Manuel, Jones, Gregg S., Hung, Magdeleine, Mukund, Susmith, Han, Bin, Liu, Xiaohong, Babaoglu, Kerim, Lansdon, Eric, Chen, Xiaowu, Todd, Jacob, Cai, Terrence, Pagratis, Nikos, Sakowicz, Roman, Geleziunas, Romas
Published in The Journal of biological chemistry (27.11.2009)
Published in The Journal of biological chemistry (27.11.2009)
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Journal Article
Investigation of orexin-2 selective receptor antagonists: Structural modifications resulting in dual orexin receptor antagonists
Skudlarek, Jason W., DiMarco, Christina N., Babaoglu, Kerim, Roecker, Anthony J., Bruno, Joseph G., Pausch, Mark A., O'Brien, Julie A., Cabalu, Tamara D., Stevens, Joanne, Brunner, Joseph, Tannenbaum, Pamela L., Wuelfing, W. Peter, Garson, Susan L., Fox, Steven V., Savitz, Alan T., Harrell, Charles M., Gotter, Anthony L., Winrow, Christopher J., Renger, John J., Kuduk, Scott D., Coleman, Paul J.
Published in Bioorganic & medicinal chemistry letters (15.03.2017)
Published in Bioorganic & medicinal chemistry letters (15.03.2017)
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Journal Article
New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action
Tsiang, Manuel, Jones, Gregg S., Niedziela-Majka, Anita, Kan, Elaine, Lansdon, Eric B., Huang, Wayne, Hung, Magdeleine, Samuel, Dharmaraj, Novikov, Nikolai, Xu, Yili, Mitchell, Michael, Guo, Hongyan, Babaoglu, Kerim, Liu, Xiaohong, Geleziunas, Romas, Sakowicz, Roman
Published in The Journal of biological chemistry (15.06.2012)
Published in The Journal of biological chemistry (15.06.2012)
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Journal Article
Discovery of 6‑(Fluoro-18 F)‑3-(1H‑pyrrolo[2,3‑c]pyridin-1-yl)isoquinolin-5-amine ([18F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)
Walji, Abbas M, Hostetler, Eric D, Selnick, Harold, Zeng, Zhizhen, Miller, Patricia, Bennacef, Idriss, Salinas, Cristian, Connolly, Brett, Gantert, Liza, Holahan, Marie, O’Malley, Stacey, Purcell, Mona, Riffel, Kerry, Li, Jing, Balsells, Jaume, OBrien, Julie A, Melquist, Stacey, Soriano, Aileen, Zhang, Xiaoping, Ogawa, Aimie, Xu, Serena, Joshi, Elizabeth, Della Rocca, Joseph, Hess, Fred J, Schachter, Joel, Hesk, David, Schenk, David, Struyk, Arie, Babaoglu, Kerim, Lohith, Talakad G, Wang, Yaode, Yang, Kun, Fu, Jianmin, Evelhoch, Jeffrey L, Coleman, Paul J
Published in Journal of medicinal chemistry (26.05.2016)
Published in Journal of medicinal chemistry (26.05.2016)
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Journal Article
Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy
Skudlarek, Jason W, Cooke, Andrew J, Mitchell, Helen J, Babaoglu, Kerim, Shaw, Anthony W, Tong, Ling, Nomland, Ashley B, Labroli, Marc, Sha, Deyou, Mulhearn, James J, Wu, Chengwei, Li, Sarah W, Beshore, Douglas C, Hughes, Jonathan M E, Jouffroy, Matthieu, Wang, Hao, Balibar, Carl J, Painter, Ronald E, Shen, Pamela, Lange, Henry S, Ishchenko, Andrii, Chen, Yun-Ting, Klein, Daniel J, Tracy, Rodger W, Miller, Randy R, Cabalu, Tamara D, Wu, Zhe, Leithead, Andrew, Scapin, Giovanna, Hruza, Alan W, Dzhekieva, Liudmila, Bukhtiyarova, Marina, Homsher, Michelle F, Xu, Min, Bahnck-Teets, Carolyn, McKenney, David, Buevich, Alexei V, Liu, Jian, Zhang, Li-Kang, Meng, Tao, Kelly, Terri, DiNunzio, Edward, Soisson, Stephen, Cheng, Robert K Y, Hennig, Michael, Raheem, Izzat, Walker, Scott S
Published in Journal of medicinal chemistry (12.09.2024)
Published in Journal of medicinal chemistry (12.09.2024)
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Journal Article
Design, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as β-Lactamase Inhibitors
Eidam, Oliv, Romagnoli, Chiara, Caselli, Emilia, Babaoglu, Kerim, Pohlhaus, Denise Teotico, Karpiak, Joel, Bonnet, Richard, Shoichet, Brian K, Prati, Fabio
Published in Journal of medicinal chemistry (11.11.2010)
Published in Journal of medicinal chemistry (11.11.2010)
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Journal Article
Comprehensive Mechanistic Analysis of Hits from High-Throughput and Docking Screens against β-Lactamase
Babaoglu, Kerim, Simeonov, Anton, Irwin, John J, Nelson, Michael E, Feng, Brian, Thomas, Craig J, Cancian, Laura, Costi, M. Paola, Maltby, David A, Jadhav, Ajit, Inglese, James, Austin, Christopher P, Shoichet, Brian K
Published in Journal of medicinal chemistry (24.04.2008)
Published in Journal of medicinal chemistry (24.04.2008)
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Journal Article
Characterization of potent RSV neutralizing antibodies isolated from human memory B cells and identification of diverse RSV/hMPV cross-neutralizing epitopes
Xiao, Xiao, Tang, Aimin, Cox, Kara S, Wen, Zhiyun, Callahan, Cheryl, Sullivan, Nicole L, Nahas, Deborah D, Cosmi, Scott, Galli, Jennifer D, Minnier, Michael, Verma, Deeptak, Babaoglu, Kerim, Su, Hua, Bett, Andrew J, Vora, Kalpit A, Chen, Zhifeng, Zhang, Lan
Published in mAbs (17.11.2019)
Published in mAbs (17.11.2019)
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