Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation
Uthman, Laween, Baartscheer, Antonius, Bleijlevens, Boris, Schumacher, Cees A., Fiolet, Jan W. T., Koeman, Anneke, Jancev, Milena, Hollmann, Markus W., Weber, Nina C., Coronel, Ruben, Zuurbier, Coert J.
Published in Diabetologia (01.03.2018)
Published in Diabetologia (01.03.2018)
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Empagliflozin reduces oxidative stress through inhibition of the novel inflammation/NHE/[Na+]c/ROS-pathway in human endothelial cells
Uthman, Laween, Li, Xiaoling, Baartscheer, Antonius, Schumacher, Cees A., Baumgart, Patricia, Hermanides, Jeroen, Preckel, Benedikt, Hollmann, Markus W., Coronel, Ruben, Zuurbier, Coert J., Weber, Nina C.
Published in Biomedicine & pharmacotherapy (01.02.2022)
Published in Biomedicine & pharmacotherapy (01.02.2022)
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Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients
Uthman, Laween, Baartscheer, Antonius, Schumacher, Cees A, Fiolet, Jan W T, Kuschma, Marius C, Hollmann, Markus W, Coronel, Ruben, Weber, Nina C, Zuurbier, Coert J
Published in Frontiers in physiology (21.11.2018)
Published in Frontiers in physiology (21.11.2018)
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RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling
van den Hoogenhof, Maarten M.G, Beqqali, Abdelaziz, Amin, Ahmad S, van der Made, Ingeborg, Aufiero, Simona, Khan, Mohsin A.F, Schumacher, Cees A, Jansweijer, Joeri A, van Spaendonck-Zwarts, Karin Y, Remme, Carol Ann, Backs, Johannes, Verkerk, Arie O, Baartscheer, Antonius, Pinto, Yigal M, Creemers, Esther E
Published in Circulation (New York, N.Y.) (25.09.2018)
Published in Circulation (New York, N.Y.) (25.09.2018)
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Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells
Chen, Sha, Schumacher, Cees A, Van Amersfoorth, Shirley C M, Fiolet, Jan W T, Baartscheer, Antonius, Veldkamp, Marieke W, Coronel, Ruben, Zuurbier, Coert J
Published in Frontiers in physiology (26.07.2023)
Published in Frontiers in physiology (26.07.2023)
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Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates
Knottnerus, Suzan J G, Mengarelli, Isabella, Wüst, Rob C I, Baartscheer, Antonius, Bleeker, Jeannette C, Coronel, Ruben, Ferdinandusse, Sacha, Guan, Kaomei, IJlst, Lodewijk, Li, Wener, Luo, Xiaojing, Portero, Vincent M, Ulbricht, Ying, Visser, Gepke, Wanders, Ronald J A, Wijburg, Frits A, Verkerk, Arie O, Houtkooper, Riekelt H, Bezzina, Connie R
Published in International journal of molecular sciences (08.04.2020)
Published in International journal of molecular sciences (08.04.2020)
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Sphingosine‐1‐Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning
Keul, Petra, Borren, Marcel M. G. J., Ghanem, Alexander, Müller, Frank Ulrich, Baartscheer, Antonius, Verkerk, Arie O., Stümpel, Frank, Schulte, Jan Sebastian, Hamdani, Nazha, Linke, Wolfgang A., Loenen, Pieter, Matus, Marek, Schmitz, Wilhelm, Stypmann, Jörg, Tiemann, Klaus, Ravesloot, Jan‐Hindrik, Alewijnse, Astrid E., Hermann, Sven, Spijkers, Léon J. A., Hiller, Karl‐Heinz, Herr, Deron, Heusch, Gerd, Schäfers, Michael, Peters, Stephan L. M., Chun, Jerold, Levkau, Bodo
Published in Journal of the American Heart Association (20.05.2016)
Published in Journal of the American Heart Association (20.05.2016)
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Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel
Veldkamp, Marieke W., Geuzebroek, Guillaume S. C., Baartscheer, Antonius, Verkerk, Arie O., Schumacher, Cees A., Suarez, Gedeon G., Berger, Wouter R., Casini, Simona, van Amersfoorth, Shirley C. M., Scholman, Koen T., Driessen, Antoine H. G., Belterman, Charly N. W., van Ginneken, Antoni C. G., de Groot, Joris R., de Bakker, Jacques M. T., Remme, Carol Ann, Boukens, Bas J., Coronel, Ruben
Published in Nature communications (19.10.2018)
Published in Nature communications (19.10.2018)
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A heterozygous deletion mutation in the cardiac sodium channel gene SCN5A with loss- and gain-of-function characteristics manifests as isolated conduction disease, without signs of Brugada or long QT syndrome
Zumhagen, Sven, Veldkamp, Marieke W, Stallmeyer, Birgit, Baartscheer, Antonius, Eckardt, Lars, Paul, Matthias, Remme, Carol Ann, Bhuiyan, Zahurul A, Bezzina, Connie R, Schulze-Bahr, Eric
Published in PloS one (28.06.2013)
Published in PloS one (28.06.2013)
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Ionic mechanism of delayed afterdepolarizations in ventricular cells isolated from human end-stage failing hearts
VERKERK, Arie O, VELDKAMP, Marieke W, BAARTSCHEER, Antonius, SCHUMACHER, Cees A, KLÖPPING, Corinne, VAN GINNEKEN, Antoni C. G, RAVESLOOT, Jan H
Published in Circulation (New York, N.Y.) (27.11.2001)
Published in Circulation (New York, N.Y.) (27.11.2001)
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Dietary fish oil reduces the incidence of triggered arrhythmias in pig ventricular myocytes
Berecki, Géza, Den Ruijter, Hester M, Verkerk, Arie O, Schumacher, Cees A, Baartscheer, Antonius, Bakker, Diane, Boukens, Bastiaan J, van Ginneken, Antoni C G, Fiolet, Jan W T, Opthof, Tobias, Coronel, Ruben
Published in Heart rhythm (01.11.2007)
Published in Heart rhythm (01.11.2007)
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Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits
Baartscheer, Antonius, Schumacher, Cees A., Wüst, Rob C. I., Fiolet, Jan W. T., Stienen, Ger J. M., Coronel, Ruben, Zuurbier, Coert J.
Published in Diabetologia (01.03.2017)
Published in Diabetologia (01.03.2017)
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Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts
Uthman, Laween, Nederlof, Rianne, Eerbeek, Otto, Baartscheer, Antonius, Schumacher, Cees, Buchholtz, Ninée, Hollmann, Markus W, Coronel, Ruben, Weber, Nina C, Zuurbier, Coert J
Published in Cardiovascular research (01.08.2019)
Published in Cardiovascular research (01.08.2019)
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Journal Article
Sodium-glucose co-transporter 2 inhibitor empagliflozin inhibits the cardiac Na+/H+ exchanger 1: persistent inhibition under various experimental conditions
Zuurbier, Coert J, Baartscheer, Antonius, Schumacher, Cees A, Fiolet, Jan W T, Coronel, Ruben
Published in Cardiovascular research (17.12.2021)
Published in Cardiovascular research (17.12.2021)
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PO-05-006 THE RIGHT VENTRICULAR OUTFLOW TRACT DISPLAYS A SMALL L-TYPE CALCIUM CURRENT AND TRANSIENT AMPLITUDE DUE TO A UNIQUE GENE EXPRESSION PROFILE INVOLVING SYT1
Blok, Michiel, Rivaud, Mathilde, van Wijk, Stan, Scholman, Koen T., Schumacher, Cees A., Jongbloed, Monique R., Brundel, Bianca, Coronel, Ruben, Bosada, Fernanda M., Baartscheer, Antonius, Verkerk, Arie O., Veldkamp, Marieke W., Boukens, Bas J.
Published in Heart rhythm (01.05.2024)
Published in Heart rhythm (01.05.2024)
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