Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
Baarsma, Hoeke A, Skronska-Wasek, Wioletta, Mutze, Kathrin, Ciolek, Florian, Wagner, Darcy E, John-Schuster, Gerrit, Heinzelmann, Katharina, Günther, Andreas, Bracke, Ken R, Dagouassat, Maylis, Boczkowski, Jorge, Brusselle, Guy G, Smits, Ron, Eickelberg, Oliver, Yildirim, Ali Ö, Königshoff, Melanie
Published in The Journal of experimental medicine (01.01.2017)
Published in The Journal of experimental medicine (01.01.2017)
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Journal Article
Increased Extracellular Vesicles Mediate WNT5A Signaling in Idiopathic Pulmonary Fibrosis
Martin-Medina, Aina, Lehmann, Mareike, Burgy, Olivier, Hermann, Sarah, Baarsma, Hoeke A., Wagner, Darcy E., De Santis, Martina M., Ciolek, Florian, Hofer, Thomas P., Frankenberger, Marion, Aichler, Michaela, Lindner, Michael, Gesierich, Wolfgang, Guenther, Andreas, Walch, Axel, Coughlan, Christina, Wolters, Paul, Lee, Joyce S., Behr, Jürgen, Königshoff, Melanie
Published in American journal of respiratory and critical care medicine (15.12.2018)
Published in American journal of respiratory and critical care medicine (15.12.2018)
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Journal Article
Diesel exhaust particles alter mitochondrial bioenergetics and cAMP producing capacity in human bronchial epithelial cells
Cattani-Cavalieri, Isabella, Trombetta-Lima, Marina, Yan, Hong, Manzano-Covarrubias, Ana L, Baarsma, Hoeke A, Oun, Asmaa, van der Veen, Melissa Mol, Oosterhout, Emily, Dolga, Amalia M, Ostrom, Rennolds S, Valenca, Samuel Santos, Schmidt, Martina
Published in Frontiers in toxicology (25.07.2024)
Published in Frontiers in toxicology (25.07.2024)
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Journal Article
Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
Baarsma, Hoeke A, Skronska-Wasek, Wioletta, Mutze, Kathrin, Ciolek, Florian, Wagner, Darcy E, John-Schuster, Gerrit, Heinzelmann, Katharina, Günther, Andreas, Bracke, Ken R, Dagouassat, Maylis, Boczkowski, Jorge, Brusselle, Guy G, Smits, Ron, Eickelberg, Oliver, Yildirim, Ali Ö, Königshoff, Melanie
Published in The Journal of experimental medicine (01.02.2017)
Published in The Journal of experimental medicine (01.02.2017)
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Journal Article
Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle
Baarsma, Hoeke A, Han, Bing, Poppinga, Wilfred J, Driessen, Saskia, Elzinga, Carolina R S, Halayko, Andrew J, Meurs, Herman, Maarsingh, Harm, Schmidt, Martina
Published in Frontiers in cell and developmental biology (09.04.2020)
Published in Frontiers in cell and developmental biology (09.04.2020)
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Journal Article
Increased Extracellular Vesicles Mediate WNT5A Signaling in Idiopathic Pulmonary Fibrosis
Martin-Medina, Aina, Lehmann, Mareike, Burgy, Olivier, Hermann, Sarah, Baarsma, Hoeke A, Wagner, Darcy E, De Santis, Martina M, Ciolek, Florian, Hofer, Thomas P, Frankenberger, Marion, Aichler, Michaela, Lindner, Michael, Gesierich, Wolfgang, Guenther, Andreas, Walch, Axel, Coughlan, Christina, Wolters, Paul, Lee, Joyce S, Behr, Jürgen, Königshoff, Melanie
Published in American journal of respiratory and critical care medicine (15.12.2018)
Published in American journal of respiratory and critical care medicine (15.12.2018)
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Journal Article
Age dictates a steroid-resistant cascade of Wnt5a, transglutaminase 2, and leukotrienes in inflamed airways
Dietz, Katharina, MSc, de los Reyes Jiménez, Marta, MSc, Gollwitzer, Eva S., PhD, Chaker, Adam M., MD, Zissler, Ulrich M., PhD, Rådmark, Olof P., PhD, Baarsma, Hoeke A., PhD, Königshoff, Melanie, MD, PhD, Schmidt-Weber, Carsten B., PhD, Marsland, Benjamin J., PhD, Esser-von Bieren, Julia, PhD
Published in Journal of allergy and clinical immunology (01.04.2017)
Published in Journal of allergy and clinical immunology (01.04.2017)
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Journal Article
WNT Signaling in Lung Aging and Disease
Lehmann, Mareike, Baarsma, Hoeke A, Königshoff, Melanie
Published in Annals of the American Thoracic Society (01.12.2016)
Published in Annals of the American Thoracic Society (01.12.2016)
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Journal Article
Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease
Skronska-Wasek, Wioletta, Mutze, Kathrin, Baarsma, Hoeke A, Bracke, Ken R, Alsafadi, Hani N, Lehmann, Mareike, Costa, Rita, Stornaiuolo, Mariano, Novellino, Ettore, Brusselle, Guy G, Wagner, Darcy E, Yildirim, Ali Ö, Königshoff, Melanie
Published in American journal of respiratory and critical care medicine (15.07.2017)
Published in American journal of respiratory and critical care medicine (15.07.2017)
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Journal Article
TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8
Spanjer, Anita I R, Baarsma, Hoeke A, Oostenbrink, Lisette M, Jansen, Sepp R, Kuipers, Christine C, Lindner, Michael, Postma, Dirkje S, Meurs, Herman, Heijink, Irene H, Gosens, Reinoud, Königshoff, Melanie
Published in The FASEB journal (01.05.2016)
Published in The FASEB journal (01.05.2016)
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Journal Article
A drug screen with approved compounds identifies amlexanox as a novel Wnt/β‐catenin activator inducing lung epithelial organoid formation
Costa, Rita, Wagner, Darcy E., Doryab, Ali, De Santis, Martina M., Schorpp, Kenji, Rothenaigner, Ina, Lehmann, Mareike, Baarsma, Hoeke A., Liu, Xueping, Schmid, Otmar, Campillos, Monica, Yildirim, Ali Önder, Hadian, Kamyar, Königshoff, Melanie
Published in British journal of pharmacology (01.10.2021)
Published in British journal of pharmacology (01.10.2021)
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Journal Article
Noncanonical WNT-5A signaling regulates TGF-β-induced extracellular matrix production by airway smooth muscle cells
Kumawat, Kuldeep, Menzen, Mark H, Bos, I Sophie T, Baarsma, Hoeke A, Borger, Pieter, Roth, Michael, Tamm, Michael, Halayko, Andrew J, Simoons, Mirjam, Prins, Alita, Postma, Dirkje S, Schmidt, Martina, Gosens, Reinoud
Published in The FASEB journal (01.04.2013)
Published in The FASEB journal (01.04.2013)
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Journal Article
miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis
Berschneider, Barbara, Ellwanger, Daniel C., Baarsma, Hoeke A., Thiel, Cedric, Shimbori, Chiko, White, Eric S., Kolb, Martin, Neth, Peter, Königshoff, Melanie
Published in The international journal of biochemistry & cell biology (01.08.2014)
Published in The international journal of biochemistry & cell biology (01.08.2014)
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Journal Article
Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β₁ is increased in chronic obstructive pulmonary disease
Baarsma, Hoeke A, Spanjer, Anita I R, Haitsma, Gertruud, Engelbertink, Lilian H J M, Meurs, Herman, Jonker, Marnix R, Timens, Wim, Postma, Dirkje S, Kerstjens, Huib A M, Gosens, Reinoud
Published in PloS one (2011)
Published in PloS one (2011)
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Journal Article
The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices
Kistemaker, Loes E M, Oenema, Tjitske A, Baarsma, Hoeke A, Bos, I Sophie T, Schmidt, Martina, Facchinetti, Fabrizio, Civelli, Maurizio, Villetti, Gino, Gosens, Reinoud
Published in American journal of physiology. Lung cellular and molecular physiology (01.09.2017)
Published in American journal of physiology. Lung cellular and molecular physiology (01.09.2017)
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Journal Article
Glycogen synthase kinase‐3 (GSK‐3) regulates TGF‐β1‐induced differentiation of pulmonary fibroblasts
Baarsma, Hoeke A, Engelbertink, Lilian HJM, Hees, Lonneke J, Menzen, Mark H, Meurs, Herman, Timens, Wim, Postma, Dirkje S, Kerstjens, Huib AM, Gosens, Reinoud
Published in British journal of pharmacology (01.06.2013)
Published in British journal of pharmacology (01.06.2013)
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Journal Article
β-Catenin signaling is required for TGF-β1-induced extracellular matrix production by airway smooth muscle cells
Baarsma, Hoeke A, Menzen, Mark H, Halayko, Andrew J, Meurs, Herman, Kerstjens, Huib A M, Gosens, Reinoud
Published in American journal of physiology. Lung cellular and molecular physiology (01.12.2011)
Published in American journal of physiology. Lung cellular and molecular physiology (01.12.2011)
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Journal Article
Glycogen synthase kinase-3 (GSK-3) regulates TGF-[beta]1-induced differentiation of pulmonary fibroblasts
Baarsma, Hoeke A, Engelbertink, Lilian HJM, Hees, Lonneke J, Menzen, Mark H, Meurs, Herman, Timens, Wim, Postma, Dirkje S, Kerstjens, Huib AM, Gosens, Reinoud
Published in British journal of pharmacology (01.06.2013)
Published in British journal of pharmacology (01.06.2013)
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Journal Article
Novel non-canonical TGF-β signaling networks: Emerging roles in airway smooth muscle phenotype and function
Yeganeh, Behzad, Mukherjee, Subhendu, Moir, Lyn M, Kumawat, Kuldeep, Kashani, Hessam H, Bagchi, Rushita A, Baarsma, Hoeke A, Gosens, Reinoud, Ghavami, Saeid
Published in Pulmonary pharmacology & therapeutics (01.02.2013)
Published in Pulmonary pharmacology & therapeutics (01.02.2013)
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Journal Article