Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets
Bye, Alexander P., Hoepel, Willianne, Mitchell, Joanne L., Jégouic, Sophie, Loureiro, Silvia, Sage, Tanya, Vidarsson, Gestur, Nouta, Jan, Wuhrer, Manfred, de Taeye, Steven, van Gils, Marit, Kriek, Neline, Cooper, Nichola, Jones, Ian, den Dunnen, Jeroen, Gibbins, Jonathan M.
Published in Blood (21.10.2021)
Published in Blood (21.10.2021)
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Journal Article
Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib
Bye, Alexander P, Kriek, Neline, Sage, Tanya, Rawlings, Suzannah J, Prodger, Catherine, Kesavan, Murali, Lees, Charlotte, Booth, Stephen, Cowen, Louise G, Shefferd, Kirsty, Desborough, Michael J, Gibbins, Jonathan M, Eyre, Toby A
Published in Haematologica (Roma) (01.05.2023)
Published in Haematologica (Roma) (01.05.2023)
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Journal Article
RXR Ligands Negatively Regulate Thrombosis and Hemostasis
Unsworth, Amanda J, Flora, Gagan D, Sasikumar, Parvathy, Bye, Alexander P, Sage, Tanya, Kriek, Neline, Crescente, Marilena, Gibbins, Jonathan M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2017)
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Journal Article
Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling
Unsworth, Amanda J, Bye, Alexander P, Sage, Tanya, Gaspar, Renato S, Eaton, Nathan, Drew, Caleb, Stainer, Alexander, Kriek, Neline, Volberding, Peter J, Hutchinson, James L, Riley, Ryan, Jones, Sarah, Mundell, Stuart J, Cui, Weiguo, Falet, Hervé, Gibbins, Jonathan M
Published in Haematologica (Roma) (01.07.2021)
Published in Haematologica (Roma) (01.07.2021)
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Journal Article
Multiple myeloma and its treatment contribute to increased platelet reactivity
Mitchell, Joanne L, Khan, Dalia, Rana, Rekha H, Kriek, Neline, Unsworth, Amanda J, Sage, Tanya, Bye, Alexander P, Laffan, Michael, Shapiro, Susan, Thakurta, Anjan, Grech, Henri, Ramasamy, Karthik, Gibbins, Jonathan M
Published in Platelets (Edinburgh) (01.12.2023)
Published in Platelets (Edinburgh) (01.12.2023)
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Journal Article
Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib
Bye, Alexander P., Unsworth, Amanda J., Desborough, Michael J., Hildyard, Catherine A.T., Appleby, Niamh, Bruce, David, Kriek, Neline, Nock, Sophie H., Sage, Tanya, Hughes, Craig E., Gibbins, Jonathan M.
Published in Blood advances (12.12.2017)
Published in Blood advances (12.12.2017)
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Journal Article
Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring
Gaspar, Renato S, Unsworth, Amanda J, Al-Dibouni, Alaa, Bye, Alexander P, Sage, Tanya, Stewart, Michelle, Wells, Sara, Cox, Roger D, Gibbins, Jonathan M, Sellayah, Dyan, E Hughes, Craig
Published in Scientific reports (14.01.2021)
Published in Scientific reports (14.01.2021)
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Journal Article
1,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis
Alatawi, Kahdr A, Ravishankar, Divyashree, Patra, Pabitra H, Bye, Alexander P, Stainer, Alexander R, Patel, Ketan, Widera, Darius, Vaiyapuri, Sakthivel
Published in Cells (Basel, Switzerland) (01.10.2021)
Published in Cells (Basel, Switzerland) (01.10.2021)
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Journal Article
Gap Junctions and Connexin Hemichannels Underpin Hemostasis and Thrombosis
VAIYAPURI, Sakthivel, JONES, Chris I, STAIN, Christopher J, BYE, Alexander P, JONES, Sarah, OVIEDO-ORTA, Ernesto, SIMON, Alexander M, MAHAUT-SMITH, Martyn P, GIBBINS, Jonathan M, SASIKUMAR, Parvathy, MORAES, Leonardo A, MUNGER, Stephanie J, WRIGHT, Joy R, ALI, Marfoua S, SAGE, Tanya, KAISER, William J, TUCKER, Katherine L
Published in Circulation (New York, N.Y.) (22.05.2012)
Published in Circulation (New York, N.Y.) (22.05.2012)
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Journal Article
The Metabolites of the Dietary Flavonoid Quercetin Possess Potent Antithrombotic Activity, and Interact with Aspirin to Enhance Antiplatelet Effects
Stainer, Alexander R., Sasikumar, Parvathy, Bye, Alexander P., Unsworth, Amanda J., Holbrook, Lisa M., Tindall, Marcus, Lovegrove, Julie A., Gibbins, Jonathan M.
Published in TH open : companion journal to thrombosis and haemostasis (01.07.2019)
Published in TH open : companion journal to thrombosis and haemostasis (01.07.2019)
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Journal Article
Ibrutinib Inhibits Platelet Integrin αIIbβ3 Outside-In Signaling and Thrombus Stability But Not Adhesion to Collagen
Bye, Alexander P, Unsworth, Amanda J, Vaiyapuri, Sakthivel, Stainer, Alexander R, Fry, Michael J, Gibbins, Jonathan M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2015)
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Journal Article
Ca 2+ waves coordinate purinergic receptor-evoked integrin activation and polarization
Bye, Alexander P, Gibbins, Jonathan M, Mahaut-Smith, Martyn P
Published in Science signaling (21.01.2020)
Published in Science signaling (21.01.2020)
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Journal Article
Cucurbitacins Elicit Anti-Platelet Activity via Perturbation of the Cytoskeleton and Integrin Function
Kriek, Neline, Nock, Sophie H., Sage, Tanya, Khalifa, Badrija, Bye, Alexander P., Mitchell, Joanne L., Thomson, Steven, McLaughlin, Mark G., Jones, Sarah, Gibbins, Jonathan M., Unsworth, Amanda J.
Published in Thrombosis and haemostasis (01.07.2022)
Published in Thrombosis and haemostasis (01.07.2022)
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Journal Article
The rate of platelet activation determines thrombus size and structure at arterial shear
Mitchell, Joanne L., Dunster, Joanne L., Kriek, Neline, Unsworth, Amanda J., Sage, Tanya, Mohammed, Yasmin M.M., De Simone, Ilaria, Taylor, Kirk A., Bye, Alexander P., Ólafsson, Geir, Brunton, Mark, Mark, Sharon, Dymott, Leanne D., Whyte, Abigail, Ruparelia, Neil, Mckenna, Charlie, Gibbins, Jonathan M., Jones, Christopher I.
Published in Journal of thrombosis and haemostasis (01.08.2023)
Published in Journal of thrombosis and haemostasis (01.08.2023)
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Journal Article
Screening and High-Throughput Platelet Assays
Bye, Alexander P, Unsworth, Amanda J, Gibbins, Jonathan M
Published in Methods in molecular biology (Clifton, N.J.) (2018)
Published in Methods in molecular biology (Clifton, N.J.) (2018)
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Journal Article
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation
Dunster, Joanne L., Unsworth, Amanda J., Bye, Alexander P., Haining, Elizabeth J., Sowa, Marcin A., Di, Ying, Sage, Tanya, Pallini, Chiara, Pike, Jeremy A., Hardy, Alexander T., Nieswandt, Bernhard, García, Ángel, Watson, Steve P., Poulter, Natalie S., Gibbins, Jonathan M., Pollitt, Alice Y.
Published in Journal of thrombosis and haemostasis (01.02.2020)
Published in Journal of thrombosis and haemostasis (01.02.2020)
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Journal Article
Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets
Sahli, Khaled A., Flora, Gagan D., Sasikumar, Parvathy, Maghrabi, Ali H., Holbrook, Lisa-Marie, AlOuda, Sarah K., Elgheznawy, Amro, Sage, Tanya, Stainer, Alexander R., Adiyaman, Recep, AboHassan, Mohammad, Crescente, Marilena, Kriek, Neline, Vaiyapuri, Sakthivel, Bye, Alexander P., Unsworth, Amanda J., Jones, Chris I., McGuffin, Liam J., Gibbins, Jonathan M.
Published in Blood (11.02.2021)
Published in Blood (11.02.2021)
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Journal Article
Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets
Unsworth, Amanda J, Bye, Alexander P, Tannetta, Dionne S, Desborough, Michael J.R, Kriek, Neline, Sage, Tanya, Allan, Harriet E, Crescente, Marilena, Yaqoob, Parveen, Warner, Timothy D, Jones, Chris I, Gibbins, Jonathan M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2017)
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Journal Article