Sustained Drug Release from Smart Nanoparticles in Cancer Therapy: A Comprehensive Review
Bai, Xue, Smith, Zara L, Wang, Yuheng, Butterworth, Sam, Tirella, Annalisa
Published in Micromachines (Basel) (28.09.2022)
Published in Micromachines (Basel) (28.09.2022)
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Journal Article
The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication
Zhuang, Xiaodong, Magri, Andrea, Hill, Michelle, Lai, Alvina G., Kumar, Abhinav, Rambhatla, Srinivasa Bhargav, Donald, Claire L., Lopez-Clavijo, Andrea F., Rudge, Simon, Pinnick, Katherine, Chang, Wai Hoong, Wing, Peter A. C., Brown, Ryan, Qin, Ximing, Simmonds, Peter, Baumert, Thomas F., Ray, David, Loudon, Andrew, Balfe, Peter, Wakelam, Michael, Butterworth, Sam, Kohl, Alain, Jopling, Catherine L., Zitzmann, Nicole, McKeating, Jane A.
Published in Nature communications (22.01.2019)
Published in Nature communications (22.01.2019)
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Journal Article
Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR)
Ward, Richard A, Anderton, Mark J, Ashton, Susan, Bethel, Paul A, Box, Matthew, Butterworth, Sam, Colclough, Nicola, Chorley, Christopher G, Chuaqui, Claudio, Cross, Darren A. E, Dakin, Les A, Debreczeni, Judit É, Eberlein, Cath, Finlay, M. Raymond V, Hill, George B, Grist, Matthew, Klinowska, Teresa C. M, Lane, Clare, Martin, Scott, Orme, Jonathon P, Smith, Peter, Wang, Fengjiang, Waring, Michael J
Published in Journal of medicinal chemistry (12.09.2013)
Published in Journal of medicinal chemistry (12.09.2013)
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Journal Article
Circadian control of hepatitis B virus replication
Zhuang, Xiaodong, Forde, Donall, Tsukuda, Senko, D’Arienzo, Valentina, Mailly, Laurent, Harris, James M., Wing, Peter A. C., Borrmann, Helene, Schilling, Mirjam, Magri, Andrea, Rubio, Claudia Orbegozo, Maidstone, Robert J., Iqbal, Mudassar, Garzon, Miguel, Minisini, Rosalba, Pirisi, Mario, Butterworth, Sam, Balfe, Peter, Ray, David W., Watashi, Koichi, Baumert, Thomas F., McKeating, Jane A.
Published in Nature communications (12.03.2021)
Published in Nature communications (12.03.2021)
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Journal Article
eNAMPT Is Localised to Areas of Cartilage Damage in Patients with Hip Osteoarthritis and Promotes Cartilage Catabolism and Inflammation
Philp, Ashleigh M., Butterworth, Sam, Davis, Edward T., Jones, Simon W.
Published in International journal of molecular sciences (01.07.2021)
Published in International journal of molecular sciences (01.07.2021)
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Journal Article
Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators
Tang, Siyuan, Garzon Sanz, Miguel, Smith, Oliver, Krämer, Andreas, Egbase, Daniel, Caton, Paul W., Knapp, Stefan, Butterworth, Sam
Published in Acta pharmaceutica Sinica. B (01.02.2023)
Published in Acta pharmaceutica Sinica. B (01.02.2023)
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Journal Article
Prolylcarboxypeptidase Alleviates Hypertensive Cardiac Remodeling by Regulating Myocardial Tissue Angiotensin II
Nguyen, Binh Y, Zhou, Fangchao, Binder, Pablo, Liu, Wei, Hille, Susanne S, Luo, Xiaojing, Zi, Min, Zhang, Hongyuan, Adamson, Antony, Ahmed, Fozia Z, Butterworth, Sam, Cartwright, Elizabeth J, Müller, Oliver J, Guan, Kaomei, Fitzgerald, Elizabeth M, Wang, Xin
Published in Journal of the American Heart Association (20.06.2023)
Published in Journal of the American Heart Association (20.06.2023)
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Journal Article
Oxidative Cyclization of Diols Derived from 1,5-Dienes: Formation of Enantiopure cis-Tetrahydrofurans by Using Catalytic Osmium Tetroxide; Formal Synthesis of (+)-cis-Solamin
Donohoe, Timothy J., Butterworth, Sam
Published in Angewandte Chemie International Edition (25.07.2005)
Published in Angewandte Chemie International Edition (25.07.2005)
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Journal Article
A General Oxidative Cyclization of 1,5-Dienes Using Catalytic Osmium Tetroxide
Donohoe, Timothy J., Butterworth, Sam
Published in Angewandte Chemie International Edition (24.02.2003)
Published in Angewandte Chemie International Edition (24.02.2003)
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Journal Article
Diarylamine Synthesis via Desulfinylative Smiles Rearrangement
Sephton, Thomas, Large, Jonathan M, Butterworth, Sam, Greaney, Michael F
Published in Organic letters (11.02.2022)
Published in Organic letters (11.02.2022)
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Journal Article
Synthesis of Functionalized Pyrrolidinone Scaffolds via Smiles-Truce Cascade
Sephton, Thomas, Large, Jonathan M., Butterworth, Sam, Greaney, Michael F.
Published in Organic letters (15.09.2023)
Published in Organic letters (15.09.2023)
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Journal Article
Development of Novel Protein-Drug Conjugates for the Treatment of Chronic Myelomonocytic Leukemia
Cant, Rachel, Li, Lucy Huitong, Mackinnon, May-Li, Wiseman, Daniel H, Batta, Kiran, Butterworth, Sam
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Aryne‐Enabled C−N Arylation of Anilines
Sephton, Thomas, Charitou, Anastasios, Trujillo, Cristina, Large, Jonathan M., Butterworth, Sam, Greaney, Michael F.
Published in Angewandte Chemie International Edition (04.12.2023)
Published in Angewandte Chemie International Edition (04.12.2023)
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Journal Article
XAT‐Catalysis for Intramolecular Biaryl Synthesis
Sephton, Thomas, Large, Jonathan M., Natrajan, Louise S., Butterworth, Sam, Greaney, Michael F.
Published in Angewandte Chemie International Edition (26.08.2024)
Published in Angewandte Chemie International Edition (26.08.2024)
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Journal Article
Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor
Finlay, M. Raymond V, Anderton, Mark, Ashton, Susan, Ballard, Peter, Bethel, Paul A, Box, Matthew R, Bradbury, Robert H, Brown, Simon J, Butterworth, Sam, Campbell, Andrew, Chorley, Christopher, Colclough, Nicola, Cross, Darren A. E, Currie, Gordon S, Grist, Matthew, Hassall, Lorraine, Hill, George B, James, Daniel, James, Michael, Kemmitt, Paul, Klinowska, Teresa, Lamont, Gillian, Lamont, Scott G, Martin, Nathaniel, McFarland, Heather L, Mellor, Martine J, Orme, Jonathon P, Perkins, David, Perkins, Paula, Richmond, Graham, Smith, Peter, Ward, Richard A, Waring, Michael J, Whittaker, David, Wells, Stuart, Wrigley, Gail L
Published in Journal of medicinal chemistry (23.10.2014)
Published in Journal of medicinal chemistry (23.10.2014)
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Journal Article
Design of PLGA nanoparticles for sustained release of hydroxyl-FK866 by microfluidics
Bai, Xue, Tang, Siyuan, Butterworth, Sam, Tirella, Annalisa
Published in Biomaterials advances (01.11.2023)
Published in Biomaterials advances (01.11.2023)
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Journal Article
Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention
Butterworth, Sam, Overduin, Michael, Barr, Alastair J
Published in Future medicinal chemistry (01.01.2014)
Published in Future medicinal chemistry (01.01.2014)
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Journal Article
Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes
Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.
Published in Diabetologia (01.02.2020)
Published in Diabetologia (01.02.2020)
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