Antiviral Activity of Type I, II, and III Interferons Counterbalances ACE2 Inducibility and Restricts SARS-CoV-2
Busnadiego, Idoia, Fernbach, Sonja, Pohl, Marie O, Karakus, Umut, Huber, Michael, Trkola, Alexandra, Stertz, Silke, Hale, Benjamin G
Published in mBio (10.09.2020)
Published in mBio (10.09.2020)
Get full text
Journal Article
An antiviral trap made of protein nanofibrils and iron oxyhydroxide nanoparticles
Palika, Archana, Armanious, Antonius, Rahimi, Akram, Medaglia, Chiara, Gasbarri, Matteo, Handschin, Stephan, Rossi, Antonella, Pohl, Marie O., Busnadiego, Idoia, Gübeli, Christian, Anjanappa, Ravi B., Bolisetty, Sreenath, Peydayesh, Mohammad, Stertz, Silke, Hale, Benjamin G., Tapparel, Caroline, Stellacci, Francesco, Mezzenga, Raffaele
Published in Nature nanotechnology (01.08.2021)
Published in Nature nanotechnology (01.08.2021)
Get full text
Journal Article
Critically ill COVID-19 patients with neutralizing autoantibodies against type I interferons have increased risk of herpesvirus disease
Busnadiego, Idoia, Abela, Irene A, Frey, Pascal M, Hofmaenner, Daniel A, Scheier, Thomas C, Schuepbach, Reto A, Buehler, Philipp K, Brugger, Silvio D, Hale, Benjamin G
Published in PLoS biology (05.07.2022)
Published in PLoS biology (05.07.2022)
Get full text
Journal Article
SARS-CoV-2 variants reveal features critical for replication in primary human cells
Pohl, Marie O, Busnadiego, Idoia, Kufner, Verena, Glas, Irina, Karakus, Umut, Schmutz, Stefan, Zaheri, Maryam, Abela, Irene, Trkola, Alexandra, Huber, Michael, Stertz, Silke, Hale, Benjamin G
Published in PLoS biology (24.03.2021)
Published in PLoS biology (24.03.2021)
Get full text
Journal Article
Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection
Echavarría-Consuegra, Liliana, Cook, Georgia M, Busnadiego, Idoia, Lefèvre, Charlotte, Keep, Sarah, Brown, Katherine, Doyle, Nicole, Dowgier, Giulia, Franaszek, Krzysztof, Moore, Nathan A, Siddell, Stuart G, Bickerton, Erica, Hale, Benjamin G, Firth, Andrew E, Brierley, Ian, Irigoyen, Nerea
Published in PLoS pathogens (17.06.2021)
Published in PLoS pathogens (17.06.2021)
Get full text
Journal Article
Host and viral determinants of Mx2 antiretroviral activity
Busnadiego, Idoia, Kane, Melissa, Rihn, Suzannah J, Preugschas, Hannah F, Hughes, Joseph, Blanco-Melo, Daniel, Strouvelle, Victoria P, Zang, Trinity M, Willett, Brian J, Boutell, Chris, Bieniasz, Paul D, Wilson, Sam J
Published in Journal of virology (01.07.2014)
Published in Journal of virology (01.07.2014)
Get full text
Journal Article
Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
Fernbach, Sonja, Spieler, Eva E., Busnadiego, Idoia, Karakus, Umut, Lkharrazi, Anouk, Stertz, Silke, Hale, Benjamin G.
Published in Cell reports (Cambridge) (22.03.2022)
Published in Cell reports (Cambridge) (22.03.2022)
Get full text
Journal Article
The infectious bursal disease virus RNA-binding VP3 polypeptide inhibits PKR-mediated apoptosis
Busnadiego, Idoia, Maestre, Ana M, Rodríguez, Dolores, Rodríguez, José F
Published in PloS one (09.10.2012)
Published in PloS one (09.10.2012)
Get full text
Journal Article
The VP3 factor from viruses of Birnaviridae family suppresses RNA silencing by binding both long and small RNA duplexes
Valli, Adrian, Busnadiego, Idoia, Maliogka, Varvara, Ferrero, Diego, Castón, José R, Rodríguez, José Francisco, García, Juan Antonio
Published in PloS one (25.09.2012)
Published in PloS one (25.09.2012)
Get full text
Journal Article
BRD9 is a druggable component of interferon-stimulated gene expression and antiviral activity
Börold, Jacob, Eletto, Davide, Busnadiego, Idoia, Mair, Nina K, Moritz, Eva, Schiefer, Samira, Schmidt, Nora, Petric, Philipp P, Wong, W Wei-Lynn, Schwemmle, Martin, Hale, Benjamin G
Published in EMBO reports (05.10.2021)
Published in EMBO reports (05.10.2021)
Get full text
Journal Article
Structure and Double-Stranded RNA-Binding Activity of the Birnavirus Drosophila X Virus VP3 Protein
Ferrero, Diego S, Busnadiego, Idoia, Garriga, Damià, Guerra, Pablo, Martín, María Teresa, Kremer, Leonor, Usón, Isabel, Rodriguez, José Francisco, Verdaguer, Nuria
Published in Journal of virology (28.01.2021)
Published in Journal of virology (28.01.2021)
Get full text
Journal Article
Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir
Pohl, Marie O., Busnadiego, Idoia, Marrafino, Francesco, Wiedmer, Lars, Hunziker, Annika, Fernbach, Sonja, Glas, Irina, Moroz-Omori, Elena V., Hale, Benjamin G., Caflisch, Amedeo, Stertz, Silke
Published in Journal of general virology (01.01.2021)
Published in Journal of general virology (01.01.2021)
Get full text
Journal Article
Structure and dsRNA-binding activity of the Birnavirus Drosophila X Virus VP3 protein
Ferrero, Diego S, Busnadiego, Idoia, Garriga, Damià, Guerra, Pablo, Martín, María Teresa, Kremer, Leonor, Usón, Isabel, Rodriguez, José Francisco, Verdaguer, Nuria
Published in Journal of virology (15.02.2021)
Published in Journal of virology (15.02.2021)
Get full text
Journal Article
Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV‑2 and Exhibits Broad-Spectrum Antiviral Activity
Pohl, Marie O., Martin-Sancho, Laura, Ratnayake, Ranjala, White, Kris M., Riva, Laura, Chen, Qi-Yin, Lieber, Gauthier, Busnadiego, Idoia, Yin, Xin, Lin, Samuel, Pu, Yuan, Pache, Lars, Rosales, Romel, Déjosez, Marion, Qin, Yiren, De Jesus, Paul D., Beall, Anne, Yoh, Sunnie, Hale, Benjamin G., Zwaka, Thomas P., Matsunaga, Naoko, García-Sastre, Adolfo, Stertz, Silke, Chanda, Sumit K., Luesch, Hendrik
Published in ACS infectious diseases (08.07.2022)
Published in ACS infectious diseases (08.07.2022)
Get full text
Journal Article
Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir
Pohl, Marie O, Busnadiego, Idoia, Marrafino, Francesco, Wiedmer, Lars, Hunziker, Annika, Fernbach, Sonja, Glas, Irina, Moroz-Omori, Elena V, Hale, Benjamin G, Caflisch, Amedeo, Stertz, Silke
Published in bioRxiv (03.06.2021)
Published in bioRxiv (03.06.2021)
Get full text
Paper
SARS-CoV-2 Variants Reveal Features Critical for Replication in Primary Human Cells
Pohl, Marie O, Busnadiego, Idoia, Kufner, Verena, Glas, Irina, Karakus, Umut, Schmutz, Stefan, Zaheri, Maryam, Abela, Irene, Trkola, Alexandra, Huber, Michael, Stertz, Silke, Hale, Benjamin G
Published in bioRxiv (04.03.2021)
Published in bioRxiv (04.03.2021)
Get full text
Paper
Genome-Wide CRISPR Screening Identifies BRD9 as a Druggable Component of Interferon-Stimulated Gene Expression and Antiviral Activity
Börold, Jacob, Eletto, Davide, Busnadiego, Idoia, Mair, Nina K, Moritz, Eva, Schiefer, Samira, Schmidt, Nora, Petric, Philipp P, Wong, W Wei-Lynn, Schwemmle, Martin, Hale, Benjamin G
Published in bioRxiv (04.02.2021)
Published in bioRxiv (04.02.2021)
Get full text
Paper