Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit
Busby, Robert W., Bryant, Alexander P., Bartolini, Wilmin P., Cordero, Etchell A., Hannig, Gerhard, Kessler, Marco M., Mahajan-Miklos, Shalina, Pierce, Christine M., Solinga, Robert M., Sun, Li Jing, Tobin, Jenny V., Kurtz, Caroline B., Currie, Mark G.
Published in European journal of pharmacology (15.12.2010)
Published in European journal of pharmacology (15.12.2010)
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Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation
Busby, Robert W, Kessler, Marco M, Bartolini, Wilmin P, Bryant, Alexander P, Hannig, Gerhard, Higgins, Carolyn S, Solinga, Robert M, Tobin, Jenny V, Wakefield, James D, Kurtz, Caroline B, Currie, Mark G
Published in The Journal of pharmacology and experimental therapeutics (01.01.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2013)
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A switch to feeding on cycads generates parallel accelerated evolution of toxin tolerance in two clades of Eumaeus caterpillars (Lepidoptera: Lycaenidae)
Robbins, Robert K., Cong, Qian, Zhang, Jing, Shen, Jinhui, Riera, Julia Quer, Murray, Debra, Busby, Robert C., Faynel, Christophe, Hallwachs, Winnie, Janzen, Daniel H., Grishin, Nick V.
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2021)
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Evolutionary trade-offs between male secondary sexual traits revealed by a phylogeny of the hyperdiverse tribe Eumaeini (Lepidoptera: Lycaenidae)
Valencia-Montoya, Wendy A, Quental, Tiago B, Tonini, João Filipe R, Talavera, Gerard, Crall, James D, Lamas, Gerardo, Busby, Robert C, Carvalho, Ana Paula S, Morais, Ana B, Oliveira Mega, Nicolás, Romanowski, Helena Piccoli, Liénard, Marjorie A, Salzman, Shayla, Whitaker, Melissa R L, Kawahara, Akito Y, Lohman, David J, Robbins, Robert K, Pierce, Naomi E
Published in Proceedings of the Royal Society. B, Biological sciences (12.05.2021)
Published in Proceedings of the Royal Society. B, Biological sciences (12.05.2021)
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Genomics‐based higher classification of the species‐rich hairstreaks (Lepidoptera: Lycaenidae: Eumaeini)
Robbins, Robert K., Cong, Qian, Zhang, Jing, Shen, Jinhui, Busby, Robert C., Faynel, Christophe, Duarte, Marcelo, Martins, Ananda R. P., Prieto, Carlos, Lamas, Gerardo, Grishin, Nick V.
Published in Systematic entomology (01.07.2022)
Published in Systematic entomology (01.07.2022)
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Journal Article
Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract
Bryant, Alexander P., Busby, Robert W., Bartolini, Wilmin P., Cordero, Etchell A., Hannig, Gerhard, Kessler, Marco M., Pierce, Christine M., Solinga, Robert M., Tobin, Jenny V., Mahajan-Miklos, Shalina, Cohen, Mitchell B., Kurtz, Caroline B., Currie, Mark G.
Published in Life sciences (1973) (08.05.2010)
Published in Life sciences (1973) (08.05.2010)
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Metopimazine is primarily metabolized by a liver amidase in humans
Busby, Robert W., Cai, Xiaokun, Yang, Sihyung, Ramos, Luis, Venkatarangan, Lata, Shen, Helen, Wax, Stephen, Sadeque, Abu J. M., De Colle, Cyril
Published in Pharmacology research & perspectives (01.02.2022)
Published in Pharmacology research & perspectives (01.02.2022)
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Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels
Kurth, Isabel, Yamaguchi, Norihiro, Andreu-Agullo, Celia, Tian, Helen S, Sridhar, Subhasree, Takeda, Shugaku, Gonsalves, Foster C, Loo, Jia Min, Barlas, Afsar, Manova-Todorova, Katia, Busby, Robert, Bendell, Johanna C, Strauss, James, Fakih, Marwan, McRee, Autumn J, Hendifar, Andrew E, Rosen, Lee S, Cercek, Andrea, Wasserman, Robert, Szarek, Michael, Spector, Scott L, Raza, Syed, Tavazoie, Masoud F, Tavazoie, Sohail F
Published in Science advances (08.10.2021)
Published in Science advances (08.10.2021)
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CCN1, a candidate target for zoledronic acid treatment in breast cancer
Espinoza, Ingrid, Liu, Hong, Busby, Robert, Lupu, Ruth
Published in Molecular cancer therapeutics (01.05.2011)
Published in Molecular cancer therapeutics (01.05.2011)
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Matrix detachment and proteasomal inhibitors diminish Sulf-2 expression in breast cancer cell lines and mouse xenografts
Khurana, Ashwani, Jung-Beom, Deok, He, Xiaoping, Kim, Sung-Hoon, Busby, Robert C., Lorenzon, Laura, Villa, Massimo, Baldi, Alfonso, Molina, Julian, Goetz, Matthew P., Shridhar, Viji
Published in Clinical & experimental metastasis (01.04.2013)
Published in Clinical & experimental metastasis (01.04.2013)
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Escherichia coli LipA Is a Lipoyl Synthase: In Vitro Biosynthesis of Lipoylated Pyruvate Dehydrogenase Complex from Octanoyl-Acyl Carrier Protein
Miller, J. Richard, Busby, Robert W, Jordan, Sean W, Cheek, Jennifer, Henshaw, Timothy F, Ashley, Gary W, Broderick, Joan B, Cronan, John E, Marletta, Michael A
Published in Biochemistry (Easton) (12.12.2000)
Published in Biochemistry (Easton) (12.12.2000)
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Metabolism and disposition of MM‐433593, a selective FAAH‐1 inhibitor, in monkeys
Banijamali, Ali R., Wakefield, James D., Mermerian, Ara H., Busby, Robert W.
Published in Pharmacology research & perspectives (01.10.2014)
Published in Pharmacology research & perspectives (01.10.2014)
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Amplified centrosomes in breast cancer: a potential indicator of tumor aggressiveness
D'ASSORO, Antonino B, BARRETT, Susan L, FOLK, Christopher, NEGRON, Vivian C, BOENEMAN, Kelly, BUSBY, Robert, WHITEHEAD, Clark, STIVALA, Franca, LINGLE, Wilma L, SALISBURY, Jeffrey L
Published in Breast cancer research and treatment (01.09.2002)
Published in Breast cancer research and treatment (01.09.2002)
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