Inverse agonists of the 5-HT2A receptor reduce nicotine withdrawal signs in rats
Malin, David, Henceroth, Mallori, Rao, Gadam Srinivas, Campbell, Joseph, Ma, Jian-Nong, Tsai, Ping-Hsun, Kishbaugh, Jordan C., Burstein, Ethan S.
Published in Neuroscience letters (20.11.2019)
Published in Neuroscience letters (20.11.2019)
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Journal Article
The impact of pimavanserin on psychotic phenotypes and tau phosphorylation in the P301L/COMT– and rTg(P301L)4510 mouse models of Alzheimer's disease
Jimenez, Heidy, Adrien, Leslie, Wolin, Adam, Eun, John, Chang, Eric H., Burstein, Ethan S., Gomar, Jesus, Davies, Peter, Koppel, Jeremy
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)
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Journal Article
Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
Scheepstra, Marcel, Andrei, Sebastian A, de Vries, Rens M. J. M, Meijer, Femke A, Ma, Jian-Nong, Burstein, Ethan S, Olsson, Roger, Ottmann, Christian, Milroy, Lech-Gustav, Brunsveld, Luc
Published in ACS chemical neuroscience (20.09.2017)
Published in ACS chemical neuroscience (20.09.2017)
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Structural Requirements of Transmembrane Domain 3 for Activation by the M1 Muscarinic Receptor Agonists AC-42, AC-260584, Clozapine, and N-Desmethylclozapine: Evidence for Three Distinct Modes of Receptor Activation
Spalding, Tracy A, Ma, Jian-Nong, Ott, Thomas R, Friberg, Mikael, Bajpai, Abhishek, Bradley, Stefania Risso, Davis, Robert E, Brann, Mark R, Burstein, Ethan S
Published in Molecular pharmacology (01.12.2006)
Published in Molecular pharmacology (01.12.2006)
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Journal Article
Identification and Characterization of Novel Small-Molecule Protease-Activated Receptor 2 Agonists
Gardell, Luis R, Ma, Jian-Nong, Seitzberg, Jimmi Gerner, Knapp, Anne E, Schiffer, Hans H, Tabatabaei, Ali, Davis, Christopher N, Owens, Michelle, Clemons, Bryan, Wong, Kenneth K, Lund, Birgitte, Nash, Norman R, Gao, Yan, Lameh, Jelveh, Schmelzer, Kara, Olsson, Roger, Burstein, Ethan S
Published in The Journal of pharmacology and experimental therapeutics (01.12.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2008)
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Journal Article
Preclinical PET Neuroimaging of [11C]Bexarotene
Rotstein, Benjamin H., Placzek, Michael S., Krishnan, Hema S., Pekošak, Aleksandra, Collier, Thomas Lee, Wang, Changning, Liang, Steven H., Burstein, Ethan S., Hooker, Jacob M., Vasdev, Neil
Published in Molecular imaging (2016)
Published in Molecular imaging (2016)
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Functional enhancement of AT1R potency in the presence of the TPαR is revealed by a comprehensive 7TM receptor co-expression screen
Hansen, Jonas Tind, Lyngsø, Christina, Speerschneider, Tobias, Hansen, Pernille B L, Galés, Céline, Weiner, David M, Sheikh, Søren P, Burstein, Ethan S, Hansen, Jakob Lerche
Published in PloS one (14.03.2013)
Published in PloS one (14.03.2013)
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Journal Article
Characterization of the Mas‐related gene family: structural and functional conservation of human and rhesus MrgX receptors
Burstein, Ethan S, Ott, Thomas R, Feddock, Michele, Ma, Jian‐Nong, Fuhs, Steve, Wong, Steven, Schiffer, Hans H, Brann, Mark R, Nash, Norman R
Published in British journal of pharmacology (01.01.2006)
Published in British journal of pharmacology (01.01.2006)
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Journal Article
Optimization of isochromanone based urotensin II receptor agonists
Lehmann, Fredrik, Currier, Erika A., Olsson, Roger, Ma, Jian-Nong, Burstein, Ethan S., Hacksell, Uli, Luthman, Kristina
Published in Bioorganic & medicinal chemistry (01.07.2010)
Published in Bioorganic & medicinal chemistry (01.07.2010)
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Imaging the 5-HT2C receptor with PET: Evaluation of 5-HT2C and 5-HT2A affinity of pimavanserin in the primate brain
Ridler, Khanum, Rizzo, Gaia, Burstein, Ethan S, sberg Morén, Anton, Stepanov, Vladimir, Halldin, Christer, Rabiner, Eugenii A
Published in Journal of cerebral blood flow and metabolism (21.08.2024)
Published in Journal of cerebral blood flow and metabolism (21.08.2024)
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Journal Article
Low Dose Bexarotene Treatment Rescues Dopamine Neurons and Restores Behavioral Function in Models of Parkinson’s Disease
McFarland, Krista, Spalding, Tracy A, Hubbard, David, Ma, Jian-Nong, Olsson, Roger, Burstein, Ethan S
Published in ACS chemical neuroscience (20.11.2013)
Published in ACS chemical neuroscience (20.11.2013)
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Journal Article
Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer’s disease
Yuede, Carla M., Wallace, Clare E., Davis, Todd A., Gardiner, Woodrow D., Hettinger, Jane C., Edwards, Hannah M., Hendrix, Rachel D., Doherty, Brookelyn M., Yuede, Kayla M., Burstein, Ethan S., Cirrito, John R.
Published in Journal of neurochemistry (01.03.2021)
Published in Journal of neurochemistry (01.03.2021)
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Journal Article
Pimavanserin Promotes Trophic Factor Release and Protects Cultured Primary Dopaminergic Neurons Exposed to MPP+ in a GDNF-Dependent Manner
Lavigne, Elodie Gras, Buttigieg, Dorothée, Steinschneider, Rémy, Burstein, Ethan S
Published in ACS chemical neuroscience (16.06.2021)
Published in ACS chemical neuroscience (16.06.2021)
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Journal Article
Pimavanserin reverses multiple measures of anxiety in a rodent model of post-traumatic stress disorder
Malin, David H., Tsai, Ping-Hsun, Campbell, Joseph R., Moreno, Georgina L., Chapman, Holly L., Suzaki, Aoi, Keivan, Mehrshad S., Gibbons, Kaitlyn M., Morales, Erica R., Burstein, Ethan S., Ward, Christopher P.
Published in European journal of pharmacology (15.01.2023)
Published in European journal of pharmacology (15.01.2023)
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Journal Article
Pimavanserin, a 5HT 2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease
Yuede, Carla M, Wallace, Clare E, Davis, Todd A, Gardiner, Woodrow D, Hettinger, Jane C, Edwards, Hannah M, Hendrix, Rachel D, Doherty, Brookelyn M, Yuede, Kayla M, Burstein, Ethan S, Cirrito, John R
Published in Journal of neurochemistry (01.03.2021)
Published in Journal of neurochemistry (01.03.2021)
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Journal Article
Estrogen Receptor Beta Selective Agonists as Agents to Treat Chemotherapeutic-Induced Neuropathic Pain
Ma, Jian-Nong, McFarland, Krista, Olsson, Roger, Burstein, Ethan S
Published in ACS chemical neuroscience (21.09.2016)
Published in ACS chemical neuroscience (21.09.2016)
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Journal Article
Bexarotene prodrugs: Targeting through cleavage by NQO1 (DT-diaphorase)
Schafer, Anja, Burstein, Ethan S., Olsson, Roger
Published in Bioorganic & medicinal chemistry letters (15.04.2014)
Published in Bioorganic & medicinal chemistry letters (15.04.2014)
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