Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination
Dowling, David J., Barman, Soumik, Smith, Alyson J., Borriello, Francesco, Chaney, Danielle, Brightman, Spencer E., Melhem, Gandolina, Brook, Byron, Menon, Manisha, Soni, Dheeraj, Schüller, Simone, Siram, Karthik, Nanishi, Etsuro, Bazin, Hélène G., Burkhart, David J., Levy, Ofer, Evans, Jay T.
Published in Scientific reports (18.10.2022)
Published in Scientific reports (18.10.2022)
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Intranasal administration of a synthetic TLR4 agonist INI-2004 significantly reduces allergy symptoms following therapeutic administration in a murine model of allergic sensitization
Jackson, Konner J, Buhl, Cassandra, Miller, Shannon M, Khalaf, Juhienah K, Ward, Janine, Sands, Cherrokee, Walsh, Lois, Whitacre, Margaret, Burkhart, David J, Bazin-Lee, Hélène G, Evans, Jay T
Published in Frontiers in immunology (23.07.2024)
Published in Frontiers in immunology (23.07.2024)
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Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization
Borriello, Francesco, Pietrasanta, Carlo, Lai, Jacqueline C Y, Walsh, Lois M, Sharma, Pankaj, O'Driscoll, David N, Ramirez, Juan, Brightman, Spencer, Pugni, Lorenza, Mosca, Fabio, Burkhart, David J, Dowling, David J, Levy, Ofer
Published in Frontiers in immunology (12.12.2017)
Published in Frontiers in immunology (12.12.2017)
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Co-Delivery of a Novel Lipidated TLR7/8 Agonist and Hemagglutinin-Based Influenza Antigen Using Silica Nanoparticles Promotes Enhanced Immune Responses
Abdelwahab, Walid M, Auclair, Sarah, Borgogna, Timothy, Siram, Karthik, Riffey, Alexander, Bazin, Hélène G, Cottam, Howard B, Hayashi, Tomoko, Evans, Jay T, Burkhart, David J
Published in Pharmaceutics (01.01.2024)
Published in Pharmaceutics (01.01.2024)
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Methylglycol chitosan and a synthetic TLR4 agonist enhance immune responses to influenza vaccine administered sublingually
Spinner, Justin L, Oberoi, Hardeep S, Yorgensen, Yvonne M, Poirier, Danielle S, Burkhart, David J, Plante, Martin, Evans, Jay T
Published in Vaccine (26.10.2015)
Published in Vaccine (26.10.2015)
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Co-Delivery of Novel Synthetic TLR4 and TLR7/8 Ligands Adsorbed to Aluminum Salts Promotes Th1-Mediated Immunity against Poorly Immunogenic SARS-CoV-2 RBD
Siram, Karthik, Lathrop, Stephanie K, Abdelwahab, Walid M, Tee, Rebekah, Davison, Clara J, Partlow, Haley A, Evans, Jay T, Burkhart, David J
Published in Vaccines (Basel) (23.12.2023)
Published in Vaccines (Basel) (23.12.2023)
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A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice
Miller, Shannon M., Crouse, Bethany, Hicks, Linda, Amin, Hardik, Cole, Shelby, Bazin, Helene G., Burkhart, David J., Pravetoni, Marco, Evans, Jay T.
Published in npj vaccines (10.07.2023)
Published in npj vaccines (10.07.2023)
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Using Dual Toll-like Receptor Agonism to Drive Th1-Biased Response in a Squalene- and α-Tocopherol-Containing Emulsion for a More Effective SARS-CoV-2 Vaccine
Short, Kristopher K, Lathrop, Stephanie K, Davison, Clara J, Partlow, Haley A, Kaiser, Johnathan A, Tee, Rebekah D, Lorentz, Elizabeth B, Evans, Jay T, Burkhart, David J
Published in Pharmaceutics (12.07.2022)
Published in Pharmaceutics (12.07.2022)
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PEG modified liposomes containing CRX-601 adjuvant in combination with methylglycol chitosan enhance the murine sublingual immune response to influenza vaccination
Oberoi, Hardeep S., Yorgensen, Yvonne M., Morasse, Audrey, Evans, Jay T., Burkhart, David J.
Published in Journal of controlled release (10.02.2016)
Published in Journal of controlled release (10.02.2016)
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Co-adsorption of synthetic Mincle agonists and antigen to silica nanoparticles for enhanced vaccine activity: A formulation approach to co-delivery
Abdelwahab, Walid M., Riffey, Alexander, Buhl, Cassie, Johnson, Craig, Ryter, Kendal, Evans, Jay T., Burkhart, David J.
Published in International journal of pharmaceutics (25.01.2021)
Published in International journal of pharmaceutics (25.01.2021)
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Promotion of Th17 Polarized Immunity via Co-Delivery of Mincle Agonist and Tuberculosis Antigen Using Silica Nanoparticles
Abdelwahab, Walid M., Le-Vinh, Bao, Riffey, Alexander, Hicks, Linda, Buhl, Cassandra, Ettenger, George, Jackson, Konner J., Weiss, Adam M., Miller, Shannon, Ryter, Kendal, Evans, Jay T., Burkhart, David J.
Published in ACS applied bio materials (17.06.2024)
Published in ACS applied bio materials (17.06.2024)
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Isoxazole analogues bind the System Xc- transporter: Structure-activity relationship and pharmacophore model
PATEL, Sarjubhai A, RAJALE, Trideep, NATALE, Nicholas R, O'BRIEN, Erin, BURKHART, David J, NELSON, Jared K, TWAMLEY, Brendan, BLUMENFELD, Alex, SZABON-WATOLA, Monika I, GERDES, John M, BRIDGES, Richard J
Published in Bioorganic & medicinal chemistry (01.01.2010)
Published in Bioorganic & medicinal chemistry (01.01.2010)
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Design, Synthesis, and Preliminary Evaluation of Doxazolidine Carbamates as Prodrugs Activated by Carboxylesterases
Burkhart, David J, Barthel, Benjamin L, Post, Glen C, Kalet, Brian T, Nafie, Jordan W, Shoemaker, Richard K, Koch, Tad H
Published in Journal of medicinal chemistry (30.11.2006)
Published in Journal of medicinal chemistry (30.11.2006)
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Doxazolidine, a Proposed Active Metabolite of Doxorubicin That Cross-links DNA
Post, Glen C, Barthel, Benjamin L, Burkhart, David J, Hagadorn, John R, Koch, Tad H
Published in Journal of medicinal chemistry (01.12.2005)
Published in Journal of medicinal chemistry (01.12.2005)
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Preparation of chiral isoxazole carbinols via catalytic asymmetric Corey-Bakshi-Shibata reduction
Natale, Nicholas R., Rider, Kevin C., Burkhart, David J., Li, Chun, McKenzie, Andrew R., Nelson, Jared K.
Published in ARKIVOC (16.04.2010)
Published in ARKIVOC (16.04.2010)
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Catalytic Asymmetric Synthesis of Glutamate Analogues
Burkhart, David J, McKenzie, Andrew R, Nelson, Jared K, Myers, Katherine I, Zhao, Xue, Magnusson, Kathy R, Natale, Nicholas R
Published in Organic letters (15.04.2004)
Published in Organic letters (15.04.2004)
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