Dual Roles for Spt5 in Pre-mRNA Processing and Transcription Elongation Revealed by Identification of Spt5-Associated Proteins
Lindstrom, D. L., Squazzo, S. L., Muster, N., Burckin, T. A., Wachter, K. C., Emigh, C. A., McCleery, J. A., Yates, J. R., Hartzog, G. A.
Published in Molecular and Cellular Biology (01.02.2003)
Published in Molecular and Cellular Biology (01.02.2003)
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Fully modified 2' MOE oligonucleotides redirect polyadenylation
Vickers, T A, Wyatt, J R, Burckin, T, Bennett, C F, Freier, S M
Published in Nucleic acids research (15.03.2001)
Published in Nucleic acids research (15.03.2001)
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Exploring functional relationships between components of the gene expression machinery
Ares, Manuel, Burckin, Todd, Nagel, Roland, Mandel-Gutfreund, Yael, Shiue, Lily, Clark, Tyson A, Chong, Jean-Leon, Chang, Tien-Hsien, Squazzo, Sharon, Hartzog, Grant
Published in Nature structural & molecular biology (01.02.2005)
Published in Nature structural & molecular biology (01.02.2005)
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Absolute bioavailability of 2'-O-(2-methoxyethyl)-modified antisense oligonucleotides following intraduodenal instillation in rats
Geary, R S, Khatsenko, O, Bunker, K, Crooke, R, Moore, M, Burckin, T, Truong, L, Sasmor, H, Levin, A A
Published in The Journal of pharmacology and experimental therapeutics (01.03.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.2001)
Journal Article
Comparison of the pharmacokinetics of subcutaneous and intravenous administration of a phosphorothioate oligodeoxynucleotide in cynomolgus monkeys
Leeds, J M, Henry, S P, Geary, R, Burckin, T, Levin, A A
Published in Antisense & nucleic acid drug development (01.12.2000)
Published in Antisense & nucleic acid drug development (01.12.2000)
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Pharmacokinetics and Metabolism in Mice of a Phosphorothioate Oligonucleotide Antisense Inhibitor of C-raf-1 Kinase Expression
GEARY, R. S, LEEDS, J. M, FITCHETT, J, BURCKIN, T, TRUONG, L, SPAINHOUR, C, CREEK, M, LEVIN, A. A
Published in Drug metabolism and disposition (01.11.1997)
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Published in Drug metabolism and disposition (01.11.1997)
Journal Article
Comparison of pharmacokinetics and tissue disposition of an antisense phosphorothioate oligonucleotide targeting human Ha‐ras mRNA in mouse and monkey
Yu, Rosie Z., Geary, Richard S., Leeds, Janet M., Watanabe, Tanya, Moore, Max, Fitchett, Jon, Matson, John, Burckin, Todd, Templin, Michael V., Levin, Arthur A.
Published in Journal of pharmaceutical sciences (01.02.2001)
Published in Journal of pharmaceutical sciences (01.02.2001)
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Evaluation of the renal effects of an antisense phosphorothioate oligodeoxynucleotide in monkeys
Monteith, D K, Horner, M J, Gillett, N A, Butler, M, Geary, R, Burckin, T, Ushiro-Watanabe, T, Levin, A A
Published in Toxicologic pathology (01.05.1999)
Published in Toxicologic pathology (01.05.1999)
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Pharmacokinetic Properties of Phosphorothioate Oligonucleotides
Leeds, Janet M., Geary, Richard S., Henry, Scott P., Glover, Jo, Shanahan, William, Fitchett, Jon, Burckin, Todd, Tmong, LoAnne, Levin, Arthur A.
Published in Nucleosides & nucleotides (01.07.1997)
Published in Nucleosides & nucleotides (01.07.1997)
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