Total Synthesis of Thiostrepton. Retrosynthetic Analysis and Construction of Key Building Blocks
Nicolaou, K. C, Safina, Brian S, Zak, Mark, Lee, Sang Hyup, Nevalainen, Marta, Bella, Marco, Estrada, Anthony A, Funke, Christian, Zécri, Frédéric J, Bulat, Stephan
Published in Journal of the American Chemical Society (10.08.2005)
Published in Journal of the American Chemical Society (10.08.2005)
Get full text
Journal Article
The design of potent and selective inhibitors of DPP-4: Optimization of ADME properties by amide replacements
Nordhoff, Sonja, Bulat, Stephan, Cerezo-Gálvez, Silvia, Hill, Oliver, Hoffmann-Enger, Barbara, López-Canet, Meritxell, Rosenbaum, Claudia, Rummey, Christian, Thiemann, Meinolf, Matassa, Victor G., Edwards, Paul J., Feurer, Achim
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
Get full text
Journal Article
A Biomimetically Inspired Synthesis of the Dehydropiperidine Domain of Thiostrepton
Nicolaou, K. C., Nevalainen, Marta, Safina, Brian S., Zak, Mark, Bulat, Stephan
Published in Angewandte Chemie International Edition (03.06.2002)
Published in Angewandte Chemie International Edition (03.06.2002)
Get full text
Journal Article
From lead to preclinical candidate: Optimization of β-homophenylalanine based inhibitors of dipeptidyl peptidase IV
Nordhoff, Sonja, López-Canet, Meritxell, Hoffmann-Enger, Barbara, Bulat, Stephan, Cerezo-Gálvez, Silvia, Hill, Oliver, Rosenbaum, Claudia, Rummey, Christian, Thiemann, Meinolf, Matassa, Victor G., Edwards, Paul J., Feurer, Achim
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Get full text
Journal Article
Synthetic Studies on Thiostrepton: Construction of Thiostrepton Analogues with the Thiazoline-Containing Macrocycle
Nicolaou, K. C., Nevalainen, Marta, Zak, Mark, Bulat, Stephan, Bella, Marco, Safina, Brian S.
Published in Angewandte Chemie International Edition (28.07.2003)
Published in Angewandte Chemie International Edition (28.07.2003)
Get full text
Journal Article
Combinatorial approaches to functional models for galactose oxidase
Berkessel, Albrecht, Dousset, Magali, Bulat, Stephan, Glaubitz, Katja
Published in Biological chemistry (01.10.2005)
Published in Biological chemistry (01.10.2005)
Get full text
Journal Article
A Biomimetically Inspired Synthesis of the Dehydropiperidine Domain of Thiostrepton We thank Drs. D. H. Huang and L. Pasternack, G. Suizdak, and R. Chadja for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), fellowships from The Academy of Finland (M.N.), The Skaggs Institute for Research (M.Z.), and Bayer AG (S.B.), and gr
Nicolaou, K. C., Nevalainen, Marta, Safina, Brian S., Zak, Mark, Bulat, Stephan
Published in Angewandte Chemie International Edition (03.06.2002)
Published in Angewandte Chemie International Edition (03.06.2002)
Get full text
Journal Article
A Biomimetically Inspired Synthesis of the Dehydropiperidine Domain of Thiostrepton
Nicolaou, K. C., Nevalainen, Marta, Safina, Brian S., Zak, Mark, Bulat, Stephan
Published in Angewandte Chemie (03.06.2002)
Published in Angewandte Chemie (03.06.2002)
Get full text
Journal Article
A Biomimetically Inspired Synthesis of the Dehydropiperidine Domain of Thiostrepton We thank Drs. D. H. Huang and L. Pasternack, G. Suizdak, and R. Chadja for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), fellowships from The Academy of Finland (M.N.), The Skaggs Institute for Research (M.Z.), and Bayer AG (S.B.), and gr
Nicolaou, K. C., Nevalainen, Marta, Safina, Brian S., Zak, Mark, Bulat, Stephan
Published in Angewandte Chemie (03.06.2002)
Published in Angewandte Chemie (03.06.2002)
Get full text
Journal Article
Phenylpiperidine derivatives as melanocortin-4 receptor modulators
DEPPE, HOLGER, VON SPRECHER, ANDREAS, FEURER, ACHIM, WEYERMANN, PHILIPP, BULAT, STEPHAN, SOEBERDT, MICHAEL
Year of Publication 10.10.2007
Get full text
Year of Publication 10.10.2007
Patent
Substituted aryl or heteroarylpiperidine derivatives as melanocortin-4 receptor modulators
HOFFMANN-ENGER, BARBARA, VON SPRECHER, ANDREAS, DEPPE, HOLGER, LESCOP, CYRILLE, FEURER, ACHIM, WEYERMANN, PHILIPPP, BULAT, STEPHAN, SOEBERDT, MICHAEL, NORDHOFF, SONJA
Year of Publication 04.02.2009
Get full text
Year of Publication 04.02.2009
Patent
Dpp-IV inhibitors
HOFFMANN-ENGER, BARBARA, RUMMEY, CHRISTIAN, FEURER, ACHIM, GRAFFNER NORDBERG, MALIN, ROSENBAUM, CLAUDIA, GUSTAVSSON, ANNA-LENA, BULAT, STEPHAN, NORDHOFF, SONJA
Year of Publication 28.01.2009
Get full text
Year of Publication 28.01.2009
Patent
DPP-IV INHIBITORS
HOFFMANN-ENGER, BARBARA, RUMMEY, CHRISTIAN, FEURER, ACHIM, GRAFFNER NORDBERG, MALIN, ROSENBAUM, CLAUDIA, GUSTAVSSON, ANNA-LENA, BULAT, STEPHAN, NORDHOFF, SONJA
Year of Publication 08.01.2009
Get full text
Year of Publication 08.01.2009
Patent