Empowering therapeutic antibodies with IFN-α for cancer immunotherapy
Guo, Jun, Xiao, Yu, Iyer, Ramesh, Lu, Xin, Lake, Marc, Ladror, Uri, Harlan, John, Samanta, Tanushree, Tomlinson, Medha, Bukofzer, Gail, Donawho, Cherrie, Shoemaker, Alex, Huang, Tzu-Hsuan
Published in PloS one (08.08.2019)
Published in PloS one (08.08.2019)
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ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies
Chervin, Adam S, Stone, Jennifer D, Konieczna, Iwona, Calabrese, Kelly M, Wang, Ningyan, Haribhai, Dipica, Dong, Feng, White, Michael K, Rodriguez, Luis E, Bukofzer, Gail T, Ellis, Paul A, Cosgrove, Cormac, Hecquet, Claudie, Clarin, Jerry D, Palma, Joann P, Reilly, Edward B
Published in Molecular cancer therapeutics (01.08.2023)
Published in Molecular cancer therapeutics (01.08.2023)
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ABT-888 Confers Broad In vivo Activity in Combination with Temozolomide in Diverse Tumors
PALMA, Joann P, WANG, Yi-Chun, ZHU, Gui-Dong, PENNING, Thomas D, GIRANDA, Vincent L, ROSENBERG, Saul H, FROST, David J, DONAWHO, Cherrie K, RODRIGUEZ, Luis E, MONTGOMERY, Debra, ELLIS, Paul A, BUKOFZER, Gail, NIQUETTE, Amanda, XUESONG LIU, YAN SHI, LASKO, Loren
Published in Clinical cancer research (01.12.2009)
Published in Clinical cancer research (01.12.2009)
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Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig
Bardwell, Philip D., Staron, Matthew M., Liu, Junjian, Tao, Qingfeng, Scesney, Susanne, Bukofzer, Gail, Rodriguez, Luis E., Choi, Chee-Ho, Wang, Jennifer, Chang, Qing, Dong, Feng, Donawho, Cherrie, Wang, Jieyi, Grinnell, Christine M., Tarcsa, Edit, Hutchins, Charles, Ghayur, Tariq, Gu, Jijie
Published in Protein & cell (01.01.2018)
Published in Protein & cell (01.01.2018)
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The PARP Inhibitor, ABT-888 Potentiates Temozolomide: Correlation with Drug Levels and Reduction in PARP Activity In Vivo
PALMA, Joann P, RODRIGUEZ, Luis E, XUESONG LIU, OLSON, Amanda, SALTARELLI, Mary J, YAN SHI, STAVROPOULOS, Jason A, ZHU, Gui-Dong, PENNING, Thomas D, YAN LUO, GIRANDA, Vincent L, ROSENBERG, Saul H, BONTCHEVA-DIAZ, Velitchka D, FROST, David J, DONAWHO, Cherrie K, BOUSKA, Jennifer J, BUKOFZER, Gail, COLON-LOPEZ, Milagros, RAN GUAN, JARVIS, Kenneth, JOHNSON, Eric F, KLINGHOFER, Vered
Published in Anticancer research (01.09.2008)
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Published in Anticancer research (01.09.2008)
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Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor
Wang, Jieyi, Tucker, Lora A, Stavropoulos, Jason, Zhang, Qian, Wang, Yi-Chun, Bukofzer, Gail, Niquette, Amanda, Meulbroek, Jonathan A, Barnes, David M, Shen, Jianwei, Bouska, Jennifer, Donawho, Cherrie, Sheppard, George S, Bell, Randy L
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2008)
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Optimization of Phenyl-Substituted Benzimidazole Carboxamide Poly(ADP-Ribose) Polymerase Inhibitors: Identification of (S)-2-(2-Fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a Highly Potent and Efficacious Inhibitor
Penning, Thomas D, Zhu, Gui-Dong, Gong, Jianchun, Thomas, Sheela, Gandhi, Viraj B, Liu, Xuesong, Shi, Yan, Klinghofer, Vered, Johnson, Eric F, Park, Chang H, Fry, Elizabeth H, Donawho, Cherrie K, Frost, David J, Buchanan, Fritz G, Bukofzer, Gail T, Rodriguez, Luis E, Bontcheva-Diaz, Velitchka, Bouska, Jennifer J, Osterling, Donald J, Olson, Amanda M, Marsh, Kennan C, Luo, Yan, Giranda, Vincent L
Published in Journal of medicinal chemistry (22.04.2010)
Published in Journal of medicinal chemistry (22.04.2010)
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Journal Article
Empowering therapeutic antibodies with IFN-[alpha] for cancer immunotherapy
Guo, Jun, Xiao, Yu, Iyer, Ramesh, Lu, Xin, Lake, Marc, Ladror, Uri, Harlan, John, Samanta, Tanushree, Tomlinson, Medha, Bukofzer, Gail, Donawho, Cherrie, Shoemaker, Alex, Huang, Tzu-Hsuan
Published in PloS one (08.08.2019)
Published in PloS one (08.08.2019)
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Journal Article
Abstract 2783: Empowering therapeutic monoclonal antibodies with IFN-alpha for cancer immunotherapy
Guo, Jun, Xiao, Yu, Lyer, Ramesh B., Lake, Marc R., Ladror, Uri S., Lu, Xin, Pappano, Bill, Harlan, John E., Tomlinson, Medha J., Bukofzer, Gail T., Donawho, Cherrie K., Shoemaker, Alexander R., Huang, Tzu-Hsuan
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Optimization of Phenyl-Substituted Benzimidazole Carboxamide Poly(ADP-Ribose) Polymerase Inhibitors: Identification of ( S )-2-(2-Fluoro-4-(pyrrolidin-2-yl)phenyl)-1 H -benzimidazole-4-carboxamide (A-966492), a Highly Potent and Efficacious Inhibitor
Penning, Thomas D., Zhu, Gui-Dong, Gong, Jianchun, Thomas, Sheela, Gandhi, Viraj B., Liu, Xuesong, Shi, Yan, Klinghofer, Vered, Johnson, Eric F., Park, Chang H., Fry, Elizabeth H., Donawho, Cherrie K., Frost, David J., Buchanan, Fritz G., Bukofzer, Gail T., Rodriguez, Luis E., Bontcheva-Diaz, Velitchka, Bouska, Jennifer J., Osterling, Donald J., Olson, Amanda M., Marsh, Kennan C., Luo, Yan, Giranda, Vincent L.
Published in Journal of medicinal chemistry (22.04.2010)
Published in Journal of medicinal chemistry (22.04.2010)
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Journal Article
Optimization of Phenyl-Substituted Benzimidazole Carboxamide Poly(ADP-Ribose) Polymerase Inhibitors: Identification of (S)-2-(2-Fluoro-4-(pyrrolidin-2-yl)pheny)-1H-benzimidazole-4-carboxamide (A-966492), a Highly Potent and Efficacious Inhibitor
Penning, Thomas D., Zhu, Gui-Dong, Gong, Jianchun, Thomas, Sheela, Gandhi, Viraj B., Liu, Xuesong, Shi, Yan, Klinghofer, Vered, Johnson, Eric F., Park, Chang H., Fry, Elizabeth H., Donawho, Cherrie K., Frost, David J., Buchanan, Fritz G., Bukofzer, Gail T., Rodriguez, Luis E., Bontcheva-Diaz, Velitchka, Bouska, Jennifer J., Osterling, Donald J., Olson, Amanda M., Marsh, Kennan C., Luo, Yan, Giranda, Vincent L.
Published in Journal of medicinal chemistry (22.04.2010)
Published in Journal of medicinal chemistry (22.04.2010)
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Abstract 6308: Preclinical development of ABBV-319: a CD19-targeting glucocorticoid receptor modulator (GRM) agonist antibody-drug conjugate (ADC) for the treatment of B-cell malignancies
Chang, Chewei Anderson, Emberley, Ethan, D'Souza, Aloma L., Zhao, Weilong, Cosgrove, Cormac, Jr, Axel Hernandez, Oleksijew, Anatol, Ellis, Paul, Rodriguez, Luis, Bukofzer, Gail, Peetz, David, Assaily, Wissam, Mali, Raghuveer Singh, Liu, Wei, Xu, Danqing, Potts, Gregory K., McLoughlin, Shaun, McCarthy, Kimberley, Zhang, Zhaomei, Campbell, Jos, Sturdevant, Isabella, Zhang, Gloria, Curran, Tyler, Williams, Jon D., Boghaert, Erwin, Bruncko, Milan, Marvin, Christopher C., Hobson, Adrian, Mcpherson, Michael, Uziel, Tamar, Pysz, Marybeth, Zhao, Xi, Bankovich, Alex, Freise, Kevin J., Morgan-Lappe, Susan, Purcell, James W.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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7-Aminopyrazolo[1,5-a]pyrimidines as Potent Multitargeted Receptor Tyrosine Kinase Inhibitors
Frey, Robin R, Curtin, Michael L, Albert, Daniel H, Glaser, Keith B, Pease, Lori J, Soni, Niru B, Bouska, Jennifer J, Reuter, David, Stewart, Kent D, Marcotte, Patrick, Bukofzer, Gail, Li, Junling, Davidsen, Steven K, Michaelides, Michael R
Published in Journal of medicinal chemistry (10.07.2008)
Published in Journal of medicinal chemistry (10.07.2008)
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Abstract 858: Potent in vivo activity of the aurora kinase inhibitor ABT-348 in human acute myeloid leukemia and myelodysplastic syndrome xenograft models
Wang, Yi-Chun, Kaleta, Lance, Rodriguez, Luis E., Ellis, Paul A., Bukofzer, Gail, Clarin, Jerry, Schlessinger, Sally, Li, Junling, Glaser, Keith, Michaelides, Michael, Albert, Daniel, Tse, Chris, Palma, Joann P., Donawho, Cherrie K.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Pharmacodynamic Evaluation of Irinotecan Therapy by FDG and FLT PET/CT Imaging in a Colorectal Cancer Xenograft Model
Mudd, Sarah R., Holich, Kimberley D., Voorbach, Martin J., Cole, Todd B., Reuter, David R., Tapang, Paul, Bukofzer, Gail, Chakravartty, Arunava, Donawho, Cherrie K., Palma, Joann P., Fox, Gerard B., Day, Mark, Luo, Yanping
Published in Molecular imaging and biology (01.10.2012)
Published in Molecular imaging and biology (01.10.2012)
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Abstract B62: Potent single agent in vivo activity of the PARP inhibitor veliparib (ABT-888) in BRCA -deficient xenografts (MX-1 and Capan-1)
Donawho, Cherrie K., Rodriguez, Luis E., Ellis, Paul A., Kaleta, Lance, Bukofzer, Gail, Bontcheva-Diaz, Velitchka, Liu, Xuesong, Bouska, Jennifer, Carr, Robert, Idler, Kenneth, Zhu, Guidong, Penning, Thomas, Shoemaker, Alexander, Giranda, Vincent L., Buchanan, Fritz, Frost, David J., Palma, Joann P.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Abstract B231: Potent in vivo activity of the Aurora kinase inhibitor ABT-348 in a broad spectrum of histological types: Evaluation of efficacy, dosing/scheduling, and PK/PD
Donawho, Cherrie K., Montgomery, Debra, Rodriguez, Luis E., Wang, Yi-Chun, Ellis, Paul E., Kaleta, Lance, Bukofzer, Gail, Bouska, Jennifer, Clarin, Jerry, Schlessinger, Sally, Wang, Baole, Glaser, Keith, Michaelides, Mike, Albert, Daniel, Tse, Chris, Frost, David J., Palma, Joann P.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Abstract B14: The broad spectrum antitumor efficacy and tolerability of the RTK inhibitor, linifanib (ABT-869) alone and in combination with various cytotoxic therapies
Donawho, Cherrie K., Bukofzer, Gail, Ellis, Paul A., Montgomery, Debra A., Rodriguez, Luis E., Wang, Yi-Chun, Dai, Yujia, Davidsen, Steven K., Frost, David J., Palma, Joann P.
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Effect of ferrous and ferric chelators on transferrin-iron-macrophage interactions
Baynes, R D, Friedman, B M, Bukofzer, G T, Bothwell, T H, Macfarlane, B J, Lamparelli, R D
Published in American journal of hematology (01.09.1988)
Published in American journal of hematology (01.09.1988)
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