Structure–activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor
Bugge, Steffen, Kaspersen, Svein Jacob, Larsen, Synne, Nonstad, Unni, Bjørkøy, Geir, Sundby, Eirik, Hoff, Bård Helge
Published in European journal of medicinal chemistry (21.03.2014)
Published in European journal of medicinal chemistry (21.03.2014)
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Journal Article
Route selection in the synthesis of C-4 and C-6 substituted thienopyrimidines
Bugge, Steffen, Kaspersen, Svein Jacob, Sundby, Eirik, Hoff, Bård Helge
Published in Tetrahedron (11.11.2012)
Published in Tetrahedron (11.11.2012)
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Journal Article
Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel
Petrovic, Voin, Olaisen, Camilla, Sharma, Animesh, Nepal, Anala, Bugge, Steffen, Sundby, Eirik, Hoff, Bård Helge, Slupphaug, Geir, Otterlei, Marit
Published in Data in brief (01.06.2017)
Published in Data in brief (01.06.2017)
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Journal Article
Extended structure–activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties
Bugge, Steffen, Buene, Audun Formo, Jurisch-Yaksi, Nathalie, Moen, Ingri Ullestad, Skjønsfjell, Ellen Martine, Sundby, Eirik, Hoff, Bård Helge
Published in European journal of medicinal chemistry (01.01.2016)
Published in European journal of medicinal chemistry (01.01.2016)
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Journal Article
On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay
Petrovic, Voin, Olaisen, Camilla, Sharma, Animesh, Nepal, Anala, Bugge, Steffen, Sundby, Eirik, Hoff, Bård Helge, Slupphaug, Geir, Otterlei, Marit
Published in Analytical biochemistry (15.04.2017)
Published in Analytical biochemistry (15.04.2017)
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Journal Article
Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors
Bugge, Steffen, Moen, Ingri Ullestad, Kragseth Sylte, Kent-Ove, Sundby, Eirik, Hoff, Bård Helge
Published in European journal of medicinal chemistry (13.04.2015)
Published in European journal of medicinal chemistry (13.04.2015)
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Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines as highly potent EGFR-TK inhibitors with Src-family activity
Kaspersen, Svein Jacob, Han, Jin, Nørsett, Kristin G., Rydså, Line, Kjøbli, Eli, Bugge, Steffen, Bjørkøy, Geir, Sundby, Eirik, Hoff, Bård Helge
Published in European journal of pharmaceutical sciences (01.08.2014)
Published in European journal of pharmaceutical sciences (01.08.2014)
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Journal Article
ChemInform Abstract: Route Selection in the Synthesis of C-4 and C-6 Substituted Thienopyrimidines
Bugge, Steffen, Kaspersen, Svein Jacob, Sundby, Eirik, Hoff, Baard Helge
Published in ChemInform (12.03.2013)
Published in ChemInform (12.03.2013)
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Journal Article
4-AMINO-6-ARYL[2,3-D]PYRIMIDINES FOR THE INHIBITION OF EGFR TYROSINE KINASE
HOFF, BÅRD, SUNDBY, EIRIK, HAN, JIN, KASPERSEN, SVEIN, BUGGE, STEFFEN
Year of Publication 08.01.2015
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Year of Publication 08.01.2015
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