Search Results - "BUFI, LAURA LLAUGER" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Identification of a series of 4-[3-(quinolin-2-yl)-1,2,4-oxadiazol-5-yl]piperazinyl ureas as potent smoothened antagonist hedgehog pathway inhibitors

Identification of a series of 4-[3-(quinolin-2-yl)-1,2,4-oxadiazol-5-yl]piperazinyl ureas as potent smoothened antagonist hedgehog pathway inhibitors

by Ontoria, Jesus M., Bufi, Laura Llauger, Torrisi, Caterina, Bresciani, Alberto, Giomini, Claudia, Rowley, Michael, Serafini, Sergio, Bin, Hu, Hao, Wu, Steinkühler, Christian, Jones, Philip
Published in Bioorganic & medicinal chemistry letters (15.09.2011)

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Journal Article

Identification and SAR of novel pyrrolo[1,2- a]pyrazin-1(2 H)-one derivatives as inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1)

Identification and SAR of novel pyrrolo[1,2- a]pyrazin-1(2 H)-one derivatives as inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1)

by Pescatore, Giovanna, Branca, Danila, Fiore, Fabrizio, Kinzel, Olaf, Bufi, Laura Llauger, Muraglia, Ester, Orvieto, Federica, Rowley, Michael, Toniatti, Carlo, Torrisi, Caterina, Jones, Philip
Published in Bioorganic & medicinal chemistry letters (01.02.2010)

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Journal Article

N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists

N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists

by Muraglia, Ester, Ontoria, Jesus M., Branca, Danila, Dessole, Gabriella, Bresciani, Alberto, Fonsi, Massimiliano, Giuliano, Claudio, Llauger Bufi, Laura, Monteagudo, Edith, Palumbi, Maria Cecilia, Torrisi, Caterina, Rowley, Michael, Steinkühler, Christian, Jones, Philip
Published in Bioorganic & medicinal chemistry letters (15.09.2011)

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Journal Article

Development of substituted 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2 H)-ones as potent poly(ADP–ribose) polymerase-1 (PARP-1) inhibitors active in BRCA deficient cells

Development of substituted 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2 H)-ones as potent poly(ADP–ribose) polymerase-1 (PARP-1) inhibitors active in BRCA deficient cells

by Ferrigno, Federica, Branca, Danila, Kinzel, Olaf, Lillini, Samuele, Llauger Bufi, Laura, Monteagudo, Edith, Muraglia, Ester, Rowley, Michael, Schultz-Fademrecht, Carsten, Toniatti, Carlo, Torrisi, Caterina, Jones, Philip
Published in Bioorganic & medicinal chemistry letters (01.02.2010)

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Journal Article

Synthesis of novel fluorescent probes for the molecular chaperone Hsp90

Synthesis of novel fluorescent probes for the molecular chaperone Hsp90

by Llauger-Bufi, Laura, Felts, Sara J, Huezo, Henri, Rosen, Neal, Chiosis, Gabriela
Published in Bioorganic & medicinal chemistry letters (17.11.2003)

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Journal Article

Discovery of a Potent Class I Selective Ketone Histone Deacetylase Inhibitor with Antitumor Activity in Vivo and Optimized Pharmacokinetic Properties

Discovery of a Potent Class I Selective Ketone Histone Deacetylase Inhibitor with Antitumor Activity in Vivo and Optimized Pharmacokinetic Properties

by Kinzel, Olaf, Llauger-Bufi, Laura, Pescatore, Giovanna, Rowley, Michael, Schultz-Fademrecht, Carsten, Monteagudo, Edith, Fonsi, Massimiliano, Gonzalez Paz, Odalys, Fiore, Fabrizio, Steinkühler, Christian, Jones, Philip
Published in Journal of medicinal chemistry (11.06.2009)

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Journal Article

N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxa mide s as highly potent smoothened antagonists

N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxa mide s as highly potent smoothened antagonists

by Muraglia, Ester, Ontoria, Jesus M, Branca, Danila, Dessole, Gabriella, Bresciani, Alberto, Fonsi, Massimiliano, Giuliano, Claudio, Bufi, Laura Llauger, Monteagudo, Edith, Palumbi, Maria Cecilia, Torrisi, Caterina, Rowley, Michael, Steinkuehler, Christian, Jones, Philip
Published in Bioorganic & medicinal chemistry letters (15.09.2011)

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Journal Article

Development of substituted 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazi n -3(2H)-ones as potent poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors active in BRCA deficient cells

Development of substituted 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazi n -3(2H)-ones as potent poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors active in BRCA deficient cells

by Ferrigno, Federica, Branca, Danila, Kinzel, Olaf, Lillini, Samuele, Bufi, Laura Llauger, Monteagudo, Edith, Muraglia, Ester, Rowley, Michael, Schultz-Fademrecht, Carsten, Toniatti, Carlo, Torrisi, Caterina, Jones, Philip
Published in Bioorganic & medicinal chemistry letters (01.02.2010)

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Journal Article

Small-molecule HSP90 inhibitors

Small-molecule HSP90 inhibitors

by Smith-Jones, Peter, Larson, Steven M, He, Huazhong, Llauger-Bufi, Laura, Kim, Joungnam, Chiosis, Gabriela
Year of Publication 01.01.2019

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Patent

PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

by KINZEL, Olaf, JONES, Philip, PESCATORE, Giovanna, SCHULTZ-FADEMRECHT, Carsten, LLAUGER BUFI, Laura, FERRIGNO, Federica
Year of Publication 31.10.2018

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Patent

SMALL-MOLECULE HSP90 INHIBITORS

SMALL-MOLECULE HSP90 INHIBITORS

by Chiosis Gabriela, Larson Steven M, Llauger-Bufi Laura, He Huazhong, Kim Joungnam, Smith-Jones Peter
Year of Publication 30.11.2017

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Patent

Small-molecule HSP90 inhibitors

Small-molecule HSP90 inhibitors

by Chiosis Gabriela, Llauger-Bufi Laura, Larson Steve M, He Huazhong, Kim Joungnam, Smith-Jones Peter
Year of Publication 11.07.2017

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Patent

derivados de piridinona e piridazinona como inibidores de poli (adp-ribose) polimerase (parp)

derivados de piridinona e piridazinona como inibidores de poli (adp-ribose) polimerase (parp)

by Federica Ferrigno, Olaf Kinzel, Carsten Schultz-Fademrecht, Giovanna Pescatore, Laura Llauger Bufi, Philip Jones
Year of Publication 25.05.2021

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Patent

PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

by KINZEL, OLAF, FERRIGNO, FEDERICA, JONES, PHILIP, PESCATORE, GIOVANNA, LLAUGER BUFI, LAURA, SCHULTZ-FADEMRECHT, CARSTEN
Year of Publication 09.02.2016

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Patent

derivados de piridinona e piridazinona como inibidores de poli (adp-ribose) polimerase (parp)

derivados de piridinona e piridazinona como inibidores de poli (adp-ribose) polimerase (parp)

by Federica Ferrigno, Olaf Kinzel, Carsten Schultz-Fademrecht, Giovanna Pescatore, Laura Llauger Bufi, Philip Jones
Year of Publication 29.12.2020

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Patent

Pyridinon- og pyridazinonderivater som inhibitorer av poly(ADP-ribose)polymerase (PARP), samt farmasøytisk preparat, og farmasøytisk kombinasjon derav for anvendelse i terapi

Pyridinon- og pyridazinonderivater som inhibitorer av poly(ADP-ribose)polymerase (PARP), samt farmasøytisk preparat, og farmasøytisk kombinasjon derav for anvendelse i terapi

by Bufi, Laura Llauger, Pescatore, Giovanna, Kinzel, Olaf, Schultz-Fademrecht, Carsten, Jones, Philip, Ferrigno, Federica
Year of Publication 22.07.2019

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Patent

Pyridinone and pyridazinone derivatives as inhibitors of poly(ADP-ribose)polymerase (PARP)

Pyridinone and pyridazinone derivatives as inhibitors of poly(ADP-ribose)polymerase (PARP)

by KINZEL, OLAF, FERRIGNO, FEDERICA, PESCATORE, GIOVANNA, JONES, PHILIP, LLAUGER BUFI, LAURA, SCHULTZ-FADEMRECHT, CARSTEN
Year of Publication 26.09.2013

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Patent

Derivados de piridinona y de piridazinona como inhibidores de la poli(ADP-ribosa) polimerasa (PARP)

Derivados de piridinona y de piridazinona como inhibidores de la poli(ADP-ribosa) polimerasa (PARP)

by KINZEL, Olaf, JONES, Philip, PESCATORE, Giovanna, SCHULTZ-FADEMRECHT, Carsten, LLAUGER BUFI, Laura, FERRIGNO, Federica
Year of Publication 05.03.2019

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Patent

TRICYCLIC DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

TRICYCLIC DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

by INGENITO, RAFFAELE, SCARPELLI, RITA, JONES, PHILIP, LLAUGER BUFI, LAURA, ONTORIA ONTORIA, JESUS MARIA
Year of Publication 02.07.2013

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Patent

SMALL-MOLECULE HSP90 INHIBITORS

SMALL-MOLECULE HSP90 INHIBITORS

by LARSON STEVE M, CHIOSIS GABRIELA, HE HUAZHONG, KIM JOUNGNAM, LLAUGER-BUFI LAURA, SMITH-JONES PETER
Year of Publication 14.08.2014

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Patent