Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease
Jeppsson, Fredrik, Eketjäll, Susanna, Janson, Juliette, Karlström, Sofia, Gustavsson, Susanne, Olsson, Lise-Lotte, Radesäter, Ann-Cathrine, Ploeger, Bart, Cebers, Gvido, Kolmodin, Karin, Swahn, Britt-Marie, von Berg, Stefan, Bueters, Tjerk, Fälting, Johanna
Published in The Journal of biological chemistry (30.11.2012)
Published in The Journal of biological chemistry (30.11.2012)
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P84 - A platform for evaluating in vivo OATP1B inhibition risk in cynomolgus monkeys and translation to human
Tatosian, Daniel, Li, Ying, Michel, Kimberly, Bowman, Christine, Zepp, Lauren, Hafey, Michael, Chu, Xiaoyan, Zhang, Rena, Anderson, Ken, Bueters, Tjerk, Trujillo, Maria, Evers, Raymond
Published in Drug metabolism and pharmacokinetics (2020)
Published in Drug metabolism and pharmacokinetics (2020)
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Selective effects of carbamate pesticides on rat neuronal nicotinic acetylcholine receptors and rat brain acetylcholinesterase
Smulders, Chantal J.G.M, Bueters, Tjerk J.H, Van Kleef, Regina G.D.M, Vijverberg, Henk P.M
Published in Toxicology and applied pharmacology (01.12.2003)
Published in Toxicology and applied pharmacology (01.12.2003)
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Optimizing DMPK Properties: Experiences from a Big Pharma DMPK Department
Sohlenius-Sternbeck, Anna-Karin, Janson, Juliette, Bylund, Johan, Baranczewski, Pawel, Breitholtz-Emanuelsson, Anna, Hu, Yin, Tsoi, Carrie, Lindgren, Anders, Gissberg, Olle, Bueters, Tjerk, Briem, Sveinn, Juric, Sanja, Johansson, Jenny, Bergh, Margareta, Hoogstraate, Janet
Published in Current drug metabolism (01.03.2016)
Published in Current drug metabolism (01.03.2016)
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Partial adenosine A1 receptor agonists inhibit sarin-induced epileptiform activity in the hippocampal slice
HARRISON, Patrick K, BUETERS, Tjerk J. H, IJZERMAN, Adriaan P, VAN HELDEN, Herman P. M, TATTERSALL, John E. H
Published in European journal of pharmacology (20.06.2003)
Published in European journal of pharmacology (20.06.2003)
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Characterization of the pharmacokinetics, brain distribution, and therapeutic efficacy of the adenosine A1 receptor partial agonist 2'-deoxy-N6-cyclopentyladenosine in sarin-poisoned rats
BUETERS, Tjerk J. H, IJZERMAN, Ad P, VAN HELDEN, Herman P. M, DANHOF, Meindert
Published in Toxicology and applied pharmacology (01.10.2003)
Published in Toxicology and applied pharmacology (01.10.2003)
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Cyclopentyladenosine and some of its low-efficacy derivatives inhibit striatal synaptosomal release of acetylcholine to a similar degree
Bueters, Tjerk J.H., van Duivenvoorde, Leonie M., Danhof, Meindert, IJzerman, Ad P., van Helden, Herman P.M.
Published in European journal of pharmacology (28.11.2003)
Published in European journal of pharmacology (28.11.2003)
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A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors
Tucker, Thomas J, Embrey, Mark W, Alleyne, Candice, Amin, Rupesh P, Bass, Alan, Bhatt, Bhavana, Bianchi, Elisabetta, Branca, Danila, Bueters, Tjerk, Buist, Nicole, Ha, Sookhee N, Hafey, Mike, He, Huaibing, Higgins, John, Johns, Douglas G, Kerekes, Angela D, Koeplinger, Kenneth A, Kuethe, Jeffrey T, Li, Nianyu, Murphy, BethAnn, Orth, Peter, Salowe, Scott, Shahripour, Aurash, Tracy, Rodger, Wang, Weixun, Wu, Chengwei, Xiong, Yusheng, Zokian, Hratch J, Wood, Harold B, Walji, Abbas
Published in Journal of medicinal chemistry (25.11.2021)
Published in Journal of medicinal chemistry (25.11.2021)
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