Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
Wills-Karp, Marsha, Lajoie, Stephane, Lewkowich, Ian P, Suzuki, Yusuke, Clark, Jennifer R, Sproles, Alyssa A, Dienger, Krista, Budelsky, Alison L
Published in Nature immunology (01.10.2010)
Published in Nature immunology (01.10.2010)
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Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis
Vannella, Kevin M, Ramalingam, Thirumalai R, Borthwick, Lee A, Barron, Luke, Hart, Kevin M, Thompson, Robert W, Kindrachuk, Kristen N, Cheever, Allen W, White, Sandra, Budelsky, Alison L, Comeau, Michael R, Smith, Dirk E, Wynn, Thomas A
Published in Science translational medicine (04.05.2016)
Published in Science translational medicine (04.05.2016)
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Diesel exhaust particle induction of IL-17A contributes to severe asthma
Brandt, Eric B., MD, PhD, Kovacic, Melinda Butsch, PhD, Lee, Gerald B., MD, Gibson, Aaron M., BS, Acciani, Thomas H., BS, Le Cras, Timothy D., PhD, Ryan, Patrick H., PhD, Budelsky, Alison L., PhD, Khurana Hershey, Gurjit K., MD, PhD
Published in Journal of allergy and clinical immunology (01.11.2013)
Published in Journal of allergy and clinical immunology (01.11.2013)
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Safety and efficacy of the prostaglandin D2 receptor antagonist AMG 853 in asthmatic patients
Busse, William W., MD, Wenzel, Sally E., MD, Meltzer, Eli O., MD, Kerwin, Edward M., MD, Liu, Mark C., MD, Zhang, Nan, PhD, Chon, Yun, PhD, Budelsky, Alison L., PhD, Lin, Joseph, MD, Lin, Shao-Lee, MD, PhD
Published in Journal of allergy and clinical immunology (01.02.2013)
Published in Journal of allergy and clinical immunology (01.02.2013)
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Identification of Functional Roles for Both IL-17RB and IL-17RA in Mediating IL-25-Induced Activities
Rickel, Erika A, Siegel, Lori A, Yoon, Bo-Rin Park, Rottman, James B, Kugler, David G, Swart, David A, Anders, Penny M, Tocker, Joel E, Comeau, Michael R, Budelsky, Alison L
Published in The Journal of immunology (1950) (15.09.2008)
Published in The Journal of immunology (1950) (15.09.2008)
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Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation
Maxwell, Joseph R., Zhang, Yu, Brown, William A., Smith, Carole L., Byrne, Fergus R., Fiorino, Mike, Stevens, Erin, Bigler, Jeannette, Davis, John A., Rottman, James B., Budelsky, Alison L., Symons, Antony, Towne, Jennifer E.
Published in Immunity (Cambridge, Mass.) (20.10.2015)
Published in Immunity (Cambridge, Mass.) (20.10.2015)
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Pulmonary IL-17E (IL-25) Production and IL-17RB+ Myeloid Cell-Derived Th2 Cytokine Production Are Dependent upon Stem Cell Factor-Induced Responses during Chronic Allergic Pulmonary Disease
Dolgachev, Vladislav, Petersen, Bryan C, Budelsky, Alison L, Berlin, Aaron A, Lukacs, Nicholas W
Published in The Journal of immunology (1950) (01.11.2009)
Published in The Journal of immunology (1950) (01.11.2009)
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BTNL2, a Butyrophilin/B7-Like Molecule, Is a Negative Costimulatory Molecule Modulated in Intestinal Inflammation
Arnett, Heather A, Escobar, Sabine S, Gonzalez-Suarez, Eva, Budelsky, Alison L, Steffen, Lori A, Boiani, Norman, Zhang, Ming, Siu, Gerald, Brewer, Avery W, Viney, Joanne L
Published in The Journal of immunology (1950) (01.02.2007)
Published in The Journal of immunology (1950) (01.02.2007)
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IL25 elicits a multipotent progenitor cell population that promotes T H 2 cytokine responses
Artis, David, Saenz, Steven A, Siracusa, Mark C, Perrigoue, Jacqueline G, Spencer, Sean P, Urban Jr, Joseph F, Tocker, Joel E, Budelsky, Alison L, Kleinschek, Melanie A, Kastelein, Robert A, Kambayashi, Taku, Bhandoola, Avinash
Published in Nature (London) (29.04.2010)
Published in Nature (London) (29.04.2010)
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IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses
Saenz, Steven A, Siracusa, Mark C, Perrigoue, Jacqueline G, Spencer, Sean P, Urban, Jr, Joseph F, Tocker, Joel E, Budelsky, Alison L, Kleinschek, Melanie A, Kastelein, Robert A, Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Published in Nature (London) (29.04.2010)
Published in Nature (London) (29.04.2010)
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β-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant TH2/TH17 responses
Zhang, Zhonghua, Biagini Myers, Jocelyn M., Brandt, Eric B., Ryan, Patrick H., Lindsey, Mark, Mintz-Cole, Rachael A., Reponen, Tiina, Vesper, Stephen J., Forde, Frank, Ruff, Brandy, Bass, Stacey A., LeMasters, Grace K., Bernstein, David I., Lockey, James, Budelsky, Alison L., Khurana Hershey, Gurjit K.
Published in Journal of allergy and clinical immunology (01.01.2017)
Published in Journal of allergy and clinical immunology (01.01.2017)
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Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases
Nirula, Ajay, Nilsen, Jon, Klekotka, Paul, Kricorian, Greg, Erondu, Ngozi, Towne, Jennifer E, Russell, Chris B, Martin, David A, Budelsky, Alison L
Published in Rheumatology (Oxford, England) (01.12.2016)
Published in Rheumatology (Oxford, England) (01.12.2016)
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Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology
Petersen, Bryan C, Budelsky, Alison L, Baptist, Alan P, Schaller, Matthew A, Lukacs, Nicholas W
Published in Nature medicine (01.05.2012)
Published in Nature medicine (01.05.2012)
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Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
Xue, Xiaohua, Soroosh, Pejman, De Leon-Tabaldo, Aimee, Luna-Roman, Rosa, Sablad, Marciano, Rozenkrants, Natasha, Yu, Jingxue, Castro, Glenda, Banie, Homayon, Fung-Leung, Wai-Ping, Santamaria-Babi, Luis, Schlueter, Thomas, Albers, Michael, Leonard, Kristi, Budelsky, Alison L., Fourie, Anne M.
Published in Scientific reports (01.12.2016)
Published in Scientific reports (01.12.2016)
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IL-17RA Signaling in Airway Inflammation and Bronchial Hyperreactivity in Allergic Asthma
Willis, Cynthia R, Siegel, Lori, Leith, Anh, Mohn, Deanna, Escobar, Sabine, Wannberg, Sharon, Misura, Kira, Rickel, Erika, Rottman, James B, Comeau, Michael R, Sullivan, John K, Metz, Daniela P, Tocker, Joel, Budelsky, Alison L
Published in American journal of respiratory cell and molecular biology (01.12.2015)
Published in American journal of respiratory cell and molecular biology (01.12.2015)
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Intradermal Administration of Thymic Stromal Lymphopoietin Induces a T Cell- and Eosinophil-Dependent Systemic Th2 Inflammatory Response
Jessup, Heidi K, Brewer, Avery W, Omori, Miyuki, Rickel, Erika A, Budelsky, Alison L, Yoon, Bo-Rin Park, Ziegler, Steven F, Comeau, Michael R
Published in The Journal of immunology (1950) (15.09.2008)
Published in The Journal of immunology (1950) (15.09.2008)
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Dectin-1 and IL-17A suppress murine asthma induced by Aspergillus versicolor but not Cladosporium cladosporioides due to differences in β-glucan surface exposure
Mintz-Cole, Rachael A, Gibson, Aaron M, Bass, Stacey A, Budelsky, Alison L, Reponen, Tiina, Hershey, Gurjit K Khurana
Published in The Journal of immunology (1950) (01.10.2012)
Published in The Journal of immunology (1950) (01.10.2012)
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β-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant T H 2/T H 17 responses
Zhang, Zhonghua, Biagini Myers, Jocelyn M, Brandt, Eric B, Ryan, Patrick H, Lindsey, Mark, Mintz-Cole, Rachael A, Reponen, Tiina, Vesper, Stephen J, Forde, Frank, Ruff, Brandy, Bass, Stacey A, LeMasters, Grace K, Bernstein, David I, Lockey, James, Budelsky, Alison L, Khurana Hershey, Gurjit K
Published in Journal of allergy and clinical immunology (01.01.2017)
Published in Journal of allergy and clinical immunology (01.01.2017)
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Solving time-dependent CYP3A4 inhibition for a series of indole-phenylacetic acid dual antagonists of the PGD(2) receptors CRTH2 and DP
Johnson, Michael G., Liu, Jim (Jiwen), Li, An-Rong, van Lengerich, Bettina, Wang, Sophie, Medina, Julio C., Collins, Tassie L., Danao, Jay, Seitz, Lisa, Willee, Angela, D'Souza, Warren, Budelsky, Alison L., Fan, Peter W., Wong, Simon G. W.
Published in Bioorganic & medicinal chemistry letters (01.07.2014)
Published in Bioorganic & medicinal chemistry letters (01.07.2014)
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IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses
Saenz, Steven A., Siracusa, Mark C., Perrigoue, Jacqueline G., Spencer, Sean P., Urban Jr, Joseph F., Tocker, Joel E., Budelsky, Alison L., Kleinschek, Melanie A., Kastelein, Robert A., Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Published in Nature (London) (29.04.2010)
Published in Nature (London) (29.04.2010)
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