Discovery and Optimization of a Novel Series of N-Arylamide Oxadiazoles as Potent, Highly Selective and Orally Bioavailable Cannabinoid Receptor 2 (CB2) Agonists
Cheng, Yuan, Albrecht, Brian K, Brown, James, Buchanan, John L, Buckner, William H, DiMauro, Erin F, Emkey, Renee, Fremeau, Robert T, Harmange, Jean-Christophe, Hoffman, Beth J, Huang, Liyue, Huang, Ming, Lee, Josie Han, Lin, Fen-Fen, Martin, Matthew W, Nguyen, Hung Q, Patel, Vinod F, Tomlinson, Susan A, White, Ryan D, Xia, Xiaoyang, Hitchcock, Stephen A
Published in Journal of medicinal chemistry (28.08.2008)
Published in Journal of medicinal chemistry (28.08.2008)
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Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity
DiMauro, Erin F, Newcomb, John, Nunes, Joseph J, Bemis, Jean E, Boucher, Christina, Buchanan, John L, Buckner, William H, Cee, Victor J, Chai, Lilly, Deak, Holly L, Epstein, Linda F, Faust, Ted, Gallant, Paul, Geuns-Meyer, Stephanie D, Gore, Anu, Gu, Yan, Henkle, Brad, Hodous, Brian L, Hsieh, Faye, Huang, Xin, Kim, Joseph L, Lee, Josie H, Martin, Matthew W, Masse, Craig E, McGowan, David C, Metz, Daniela, Mohn, Deanna, Morgenstern, Kurt A, Oliveira-dos-Santos, Antonio, Patel, Vinod F, Powers, David, Rose, Paul E, Schneider, Stephen, Tomlinson, Susan A, Tudor, Yan-Yan, Turci, Susan M, Welcher, Andrew A, White, Ryan D, Zhao, Huilin, Zhu, Li, Zhu, Xiaotian
Published in Journal of medicinal chemistry (21.09.2006)
Published in Journal of medicinal chemistry (21.09.2006)
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Discovery of 4-amino-5,6-biaryl-furo[2,3- d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR
DiMauro, Erin F., Newcomb, John, Nunes, Joseph J., Bemis, Jean E., Boucher, Christina, Buchanan, John L., Buckner, William H., Cheng, Alan, Faust, Theodore, Hsieh, Faye, Huang, Xin, Lee, Josie H., Marshall, Teresa L., Martin, Matthew W., McGowan, David C., Schneider, Stephen, Turci, Susan M., White, Ryan D., Zhu, Xiaotian
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
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Erratum to “Discovery of 4-amino-5,6-biaryl-furo[2,3- d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR” [Bioorg. Med. Chem. Lett. 17 (2007) 2305–2309]
DiMauro, Erin F., Newcomb, John, Nunes, Joseph J., Bemis, Jean E., Boucher, Christina, Buchanan, John L., Buckner, William H., Cheng, Alan, Faust, Theodore, Hsieh, Faye, Huang, Xin, Lee, Josie H., Marshall, Teresa L., Martin, Matthew W., McGowan, David C., Schneider, Stephen, Turci, Susan M., White, Ryan D., Zhu, Xiaotian
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
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ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS
TEMPEST, Paul A, MASSE, Craig E, TOMLINSON, Susan Ann, ALBRECHT, Brian K, PARAS, Nick A, HODOUS, Brian L, WHITE, Ryan, THAMAN, Maya C, MCGOWAN, David C, PETTUS, Liping H, RZASA, Robert M, CHAFFEE, Stuart C, BUCKNER, William H, BUCHANAN, John L, HABGOOD, Gregory J, FALSEY, James Richard, DIMAURO, Erin F, BELLON, Steven, BEMIS, Jean E, CAO, Guo-giang, DEAK, Holly L, LIU, Gang, XU, Shimin, SMITH, Adrian Leonard, HERBERICH, Bradley J, CEE, Victor J, PATEL, Vinod F, ZHANG, Dawei, KIM, Joseph L, MARTIN, Matthew W, SHAM, Kelvin, GRACEFFA, Russell, TASKER, Andrew, REED, Anthony, HARMANGE, Jean-christophe, CHAKRABARTI, Partha P, DEMORIN, Frenel F, GEUNS-MEYER, Stephanie D, OLIVIERI, Philip R
Year of Publication 02.10.2019
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Year of Publication 02.10.2019
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Furanopyrimidines
Buchanan, John Laird, Buckner, William H, Burkitt, Simon A, DiMauro, Erin F, Farthing, Christopher N, Frenkel, Alexander D, Harrison, Martin J, Kayser, Frank, Liu, Jinqian, Lively, Sarah E, Marshall, Teresa L, McGowan, David C, Sharma, Rajiv, Shuttleworth, Stephen J, Zhu, Xiaotian
Year of Publication 17.08.2010
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Year of Publication 17.08.2010
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Furanopyrimidines
BURKITT SIMON A, MARSHALL TERESA L, DIMAURO ERIN F, ZHU XIAOTIAN, FRENKEL ALEXANDER D, LIU JINQIAN, MCGOWAN DAVID C, HARRISON MARTIN J, BUCHANAN JOHN LAIRD, BUCKNER WILLIAM H, FARTHING CHRISTOPHER N, LIVELY SARAH E, KAYSER FRANK, SHARMA RAJIV, SHUTTLEWORTH STEPHEN J
Year of Publication 17.08.2010
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Year of Publication 17.08.2010
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Substituted pyrazolo[3,4-d]pyrimidines as ACK-1 and LCK inhibitors
CARDOZO MARIO G, DIMAURO ERIN F, ZHU XIAOTIAN, WHITE RYAN, HAO XIAOLIN, FU JIASHENG, BUCHANAN JOHN L, MASSE CRAIG E, BUCKNER WILLIAM H, JIAO XIAN YUN, KOPECKY DAVID J, TOMLINSON SUSAN A, KAYSER FRANK
Year of Publication 27.07.2010
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Year of Publication 27.07.2010
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Substituted pyrazolo[3,4-d]pyrimidines as ACK-1 and LCK inhibitors
Buchanan, John L, Buckner, William H, Cardozo, Mario G, DiMauro, Erin F, Fu, Jiasheng, Hao, Xiaolin, Jiao, Xian Yun, Kayser, Frank, Kopecky, David J, Masse, Craig E, Tomlinson, Susan A, White, Ryan, Zhu, Xiaotian
Year of Publication 27.07.2010
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Year of Publication 27.07.2010
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Compounds and methods of use
Potashman, Michele, Kim, Tae-Seong, Bellon, Steven, Booker, Shon, Cheng, Yuan, Kim, Joseph L, Tasker, Andrew, Xi, Ning, Xu, Shimin, Harmange, Jean-Christophe, Borg, George, Weiss, Matthew, Hodous, Brian L, Graceffa, Russell, Buckner, William H, Masse, Craig E, Choquette, Deborah, Martin, Matthew W, Germain, Julie, DiPietro, Lucian V, Chaffee, Stuart C, Nunes, Joseph J, Buchanan, John L, McGowan, David C, Whittington, Douglas A, Habgood, Gregory J, Patel, Vinod F, La, Daniel
Year of Publication 15.05.2012
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Year of Publication 15.05.2012
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Compounds and methods of use
WHITTINGTON DOUGLAS A, KIM TAE-SEONG, BOOKER SHON, NUNES JOSEPH J, MCGOWAN DAVID C, LA DANIEL, XU SHIMIN, WEISS MATTHEW, MASSE CRAIG E, PATEL VINOD F, HARMANGE JEANRISTOPHE, POTASHMAN MICHELE, BORG GEORGE, HABGOOD GREGORY J, XI NING, HODOUS BRIAN L, DIPIETRO LUCIAN V, BUCHANAN JOHN L, TASKER ANDREW, CHOQUETTE DEBORAH, GRACEFFA RUSSELL, BUCKNER WILLIAM H, GERMAIN JULIE, MARTIN MATTHEW W, KIM JOSEPH L, CHENG YUAN, BELLON STEVEN, CHAFFEE STUART C
Year of Publication 15.05.2012
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Year of Publication 15.05.2012
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ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND METHODS OF USE
WHITE, RYAN, CEE, VICTOR J, OLIVIERI, PHILIP R, PATEL, VINOD F, GRACEFFA, RUSSELL, BEMIS, JEAN E, HERBERICH, BRADLEY J, TOMLINSON, SUSAN ANN, HARMANGE, JEANRISTOPHE, LIU, GANG, DEMORIN, FRENEL F, CHAKRABARTI, PARTHA P, MARTIN, MATTHEW W, TEMPEST, PAUL A, ZHANG, DAWEI, XU, SHIMIN, DIMAURO, ERIN F, SHAM, KELVIN, PARAS, NICK A, BELLON, STEVEN, SMITH, ADRIAN LEONARD, REED, ANTHONY, ALBRECHT, BRIAN K, CAO, GUO-QIANG, THAMAN, MAYA C, RZASA, ROBERT M, DEAK, HOLLY L, KIM, JOSEPH L, GEUNS-MEYER, STEPHANIE D, MASSE, CRAIG E, BUCHANAN, JOHN L, HODOUS, BRIAN L, PETTUS, LIPING H, TASKER, ANDREW, FALSEY, JAMES RICHARD, MCGOWAN, DAVID C, CHAFFEE, STUART C, BUCKNER, WILLIAM H, HABGOOD, GREGORY J
Year of Publication 06.12.2011
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Year of Publication 06.12.2011
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PYRAZOLOPYRIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS USEFUL AS KINASE ENZYMES MODULATORS
WHITE, RYAN, DIMAURO, ERIN F, TOMLINSON, SUSAN A, HAO, XIAOLIN, MASSE, CRAIG E, BUCHANAN, JOHN L, FU, JIASHENG, ZHU, XIAOTIAN, JIAO, XIANYUN, KAYSER, FRANK, CARDOZO, MARIO G, BUCKNER, WILLIAM H, KOPECKY, DAVID J
Year of Publication 04.06.2008
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Year of Publication 04.06.2008
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Compounds and methods of use
MATTHEW W. MARTIN, WILLIAM H. BUCKNER, RUSSELL GRACEFFA, YUAN CHENG, MATTHEW WEISS, DEBORAH CHOQUETTE, LUCIAN V. DIPIETRO, MICHELE POTASHMAN, JEANRISTOPHE HARMANGE, GREGORY J. HABGOOD, SHON BOOKER, DAVID C. MCGOWAN, DOUGLAS A. WHITTINGTON, ANDREW TASKER, CRAIG E. MASSE, BRIAN L. HODOUS, TAE-SEONG KIM, VINOD F. PATEL, STUART C. CHAFFEE, SHIMIN XU, JOHN L. BUCHANAN, DANIEL LA, NING XI, JOSEPH J. NUNES, JOSEPH L. KIM, GEORGE BORG, JULIE GERMAIN, STEVEN BELLON
Year of Publication 02.09.2010
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Year of Publication 02.09.2010
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Aryl nitrogen-containing bicyclic compounds and their use as kinase inhibitors
MATTHEW W. MARTIN, WILLIAM H. BUCKNER, ADRIAN LEONARD SMITH, HOLLY L. DEAK, RUSSELL GRACEFFA, PAUL A. TEMPEST, BRIAN K. ALBRECHT, BRADLEY J. HERBERICH, KELVIN SHAM, STEPHANIE D. GEUNS-MEYER, RYAN WHITE, NICK A. PARAS, ERIN F. DIMAURO, MAYA C. THAMAN, JEANRISTOPHE HARMANGE, GREGORY J. HABGOOD, VICTOR J. CEE, JAMES RICHARD FALSEY, DAVID C. MCGOWAN, PHILIP R. OLIVIERI, CRAIG E. MASSE, ANDREW TASKER, BRIAN L. HODOUS, SUSAN ANN TOMLINSON, GUO-QIANG CAO, VINOD F. PATEL, JEAN E. BEMIS, LIPING H. PETTUS, STUART C. CHAFFEE, SHIMIN XU, JOHN L. BUCHANAN, ROBERT M. RZASA, FRENEL F. DEMORIN, GANG LIU, JOSEPH L. KIM, PARTHA P. CHAKRABARTI, DAWEI ZHANG, STEVEN BELLON, ANTHONY REED
Year of Publication 12.08.2010
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Year of Publication 12.08.2010
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FURANOPYRIMIDINES
DIMAURO, ERIN F, FRENKEL, ALEXANDER DAVID, FARTHING, CHRISTOPHER N, HARRISON, MARTIN J, BURKITT, SIMON A, SHUTTLEWORTH, STEPHEN JOSEPH, BUCHANAN, JOHN L, SHARMA, RAJIV, LIU, JINQIAN, ZHU, XIAOTIAN, KAYSER, FRANK, MARSHALL, TERESA L, MCGOWAN, DAVID C, BUCKNER, WILLIAM H, LIVELY, SARAH E
Year of Publication 04.04.2007
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Year of Publication 04.04.2007
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Pyrazolopyridine and pyrazolopyrimidine compounds
CARDOZO MARIO G, DIMAURO ERIN F, ZHU XIAOTIAN, WHITE RYAN, HAO XIAOLIN, FU JIASHENG, BUCHANAN JOHN L, JIAO XIAN Y, MASSE CRAIG E, BUCKNER WILLIAM H, KOPECKY DAVID J, TOMLINSON SUSAN A, KAYSER FRANK
Year of Publication 29.03.2007
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Year of Publication 29.03.2007
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PYRAZOLOPYRIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS USEFUL AS KINASE ENZYMES MODULATORS
WHITE, RYAN, DIMAURO, ERIN F, TOMLINSON, SUSAN A, HAO, XIAOLIN, MASSE, CRAIG E, BUCHANAN, JOHN L, FU, JIASHENG, ZHU, XIAOTIAN, JIAO, XIANYUN, KAYSER, FRANK, CARDOZO, MARIO G, BUCKNER, WILLIAM H, KOPECKY, DAVID J
Year of Publication 01.03.2007
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Year of Publication 01.03.2007
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PYRAZOLOPYRIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS USEFUL AS KINASE ENZYMES MODULATORS
WHITE, RYAN, DIMAURO, ERIN F, TOMLINSON, SUSAN A, HAO, XIAOLIN, MASSE, CRAIG E, BUCHANAN, JOHN L, FU, JIASHENG, ZHU, XIAOTIAN, JIAO, XIANYUN, KAYSER, FRANK, CARDOZO, MARIO G, BUCKNER, WILLIAM H, KOPECKY, DAVID J
Year of Publication 01.03.2007
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Year of Publication 01.03.2007
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