ESR1 mutations—a mechanism for acquired endocrine resistance in breast cancer
Jeselsohn, Rinath, Buchwalter, Gilles, De Angelis, Carmine, Brown, Myles, Schiff, Rachel
Published in Nature reviews. Clinical oncology (01.10.2015)
Published in Nature reviews. Clinical oncology (01.10.2015)
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Journal Article
Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations
Jeselsohn, Rinath, Bergholz, Johann S., Pun, Matthew, Cornwell, MacIntosh, Liu, Weihan, Nardone, Agostina, Xiao, Tengfei, Li, Wei, Qiu, Xintao, Buchwalter, Gilles, Feiglin, Ariel, Abell-Hart, Kayley, Fei, Teng, Rao, Prakash, Long, Henry, Kwiatkowski, Nicholas, Zhang, Tinghu, Gray, Nathanael, Melchers, Diane, Houtman, Rene, Liu, X. Shirley, Cohen, Ofir, Wagle, Nikhil, Winer, Eric P., Zhao, Jean, Brown, Myles
Published in Cancer cell (12.02.2018)
Published in Cancer cell (12.02.2018)
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Journal Article
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells
Fanning, Sean W, Jeselsohn, Rinath, Dharmarajan, Venkatasubramanian, Mayne, Christopher G, Karimi, Mostafa, Buchwalter, Gilles, Houtman, René, Toy, Weiyi, Fowler, Colin E, Han, Ross, Lainé, Muriel, Carlson, Kathryn E, Martin, Teresa A, Nowak, Jason, Nwachukwu, Jerome C, Hosfield, David J, Chandarlapaty, Sarat, Tajkhorshid, Emad, Nettles, Kendall W, Griffin, Patrick R, Shen, Yang, Katzenellenbogen, John A, Brown, Myles, Greene, Geoffrey L
Published in eLife (29.11.2018)
Published in eLife (29.11.2018)
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Journal Article
ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor
Mounir, Zineb, Korn, Joshua M, Westerling, Thomas, Lin, Fallon, Kirby, Christina A, Schirle, Markus, McAllister, Gregg, Hoffman, Greg, Ramadan, Nadire, Hartung, Anke, Feng, Yan, Kipp, David Randal, Quinn, Christopher, Fodor, Michelle, Baird, Jason, Schoumacher, Marie, Meyer, Ronald, Deeds, James, Buchwalter, Gilles, Stams, Travis, Keen, Nicholas, Sellers, William R, Brown, Myles, Pagliarini, Raymond A
Published in eLife (16.05.2016)
Published in eLife (16.05.2016)
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Journal Article
Regulation of MCP-1 chemokine transcription by p53
Hacke, Katrin, Rincon-Orozco, Bladimiro, Buchwalter, Gilles, Siehler, Simone Y, Wasylyk, Bohdan, Wiesmüller, Lisa, Rösl, Frank
Published in Molecular cancer (20.04.2010)
Published in Molecular cancer (20.04.2010)
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Journal Article
The Ternary Complex Factor Net Regulates Cell Migration through Inhibition of PAI-1 Expression
Buchwalter, Gilles, Gross, Christian, Wasylyk, Bohdan
Published in Molecular and Cellular Biology (01.12.2005)
Published in Molecular and Cellular Biology (01.12.2005)
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Journal Article
Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response
Jeselsohn, Rinath M, Werner, Lillian, Regan, Meredith M, Fatima, Aquila, Gilmore, Lauren, Collins, Laura C, Beck, Andrew H, Bailey, Shannon T, He, Housheng Hansen, Buchwalter, Gilles, Brown, Myles, Iglehart, J Dirk, Richardson, Andrea, Come, Steven E
Published in PloS one (31.05.2013)
Published in PloS one (31.05.2013)
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Journal Article
Siah-1b Is a Direct Transcriptional Target of p53: Identification of the Functional p53 Responsive Element in the Siah-1b Promoter
Fiucci, Giusy, Beaucourt, Séverine, Duflaut, Dominique, Lespagnol, Alexandra, Stumptner-Cuvelette, Pamela, Géant, Anne, Buchwalter, Gilles, Tuynder, Marcel, Susini, Laurent, Lassalle, Jean-Michel, Wasylyk, Christine, Wasylyk, Bohdan, Oren, Moshe, Amson, Robert, Telerman, Adam, Charpak, Georges
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2004)
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Journal Article
Loss of Net as Repressor Leads to Constitutive Increased c-fos Transcription in Cervical Cancer Cells
van Riggelen, Jan, Buchwalter, Gilles, Soto, Ubaldo, De-Castro Arce, Johanna, Hausen, Harald zur, Wasylyk, Bohdan, Rösl, Frank
Published in The Journal of biological chemistry (04.02.2005)
Published in The Journal of biological chemistry (04.02.2005)
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Journal Article
Emergence of Constitutively Active Estrogen Receptor-α Mutations in Pretreated Advanced Estrogen Receptor-Positive Breast Cancer
JESELSOHN, Rinath, YELENSKY, Roman, ARTEAGA, Carlos L, GILTNANE, Jennifer, BALKO, Justin M, CRONIN, Maureen T, JAROSZ, Mirna, SUN, James, HAWRYLUK, Matthew, LIPSON, Doron, OTTO, Geoff, ROSS, Jeffrey S, BUCHWALTER, Gilles, DVIR, Addie, SOUSSAN-GUTMAN, Lior, WOLF, Ido, RUBINEK, Tamar, GILMORE, Lauren, SCHNITT, Stuart, COME, Steven E, PUSZTAI, Lajos, STEPHENS, Philip, BROWN, Myles, FRAMPTON, Garrett, MILLER, Vincent A, MERIC-BERNSTAM, Funda, GONZALEZ-ANGULO, Ana Maria, FERRER-LOZANO, Jaime, PEREZ-FIDALGO, Jose A, CRISTOFANILLI, Massimo, GOMEZ, Henry
Published in Clinical cancer research (01.04.2014)
Published in Clinical cancer research (01.04.2014)
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Journal Article
Embryonic transcription factor SOX9 drives breast cancer endocrine resistance
Jeselsohn, Rinath, Cornwell, MacIntosh, Pun, Matthew, Buchwalter, Gilles, Nguyen, Mai, Bango, Clyde, Huang, Ying, Kuang, Yanan, Paweletz, Cloud, Fu, Xiaoyong, Nardone, Agostina, De Angelis, Carmine, Detre, Simone, Dodson, Andrew, Mohammed, Hisham, Carroll, Jason S., Bowden, Michaela, Rao, Prakash, Long, Henry W., Li, Fugen, Dowsett, Mitchell, Schiff, Rachel, Brown, Myles
Published in Proceedings of the National Academy of Sciences - PNAS (30.05.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (30.05.2017)
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Journal Article
PDEF Promotes Luminal Differentiation and Acts as a Survival Factor for ER-Positive Breast Cancer Cells
Buchwalter, Gilles, Hickey, Michele M., Cromer, Anne, Selfors, Laura M., Gunawardane, Ruwanthi N., Frishman, Jason, Jeselsohn, Rinath, Lim, Elgene, Chi, David, Fu, Xiaoyong, Schiff, Rachel, Brown, Myles, Brugge, Joan S.
Published in Cancer cell (10.06.2013)
Published in Cancer cell (10.06.2013)
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Journal Article
아프레밀라스트 및 TYK2 억제제를 포함하는 조합 요법
BUCHWALTER GILLES, PLENGE ROBERT, TZENG TE CHEN, ADAMS MARY, CARR TIFFANY, SCHAFER PETER HENRY, BEEBE LISA
Year of Publication 06.01.2022
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Year of Publication 06.01.2022
Patent
아프레밀라스트 및 TYK2 억제제를 포함하는 조합 요법
BUCHWALTER GILLES, PLENGE ROBERT, TZENG TE CHEN, ADAMS MARY, CARR TIFFANY, SCHAFER PETER HENRY, BEEBE LISA
Year of Publication 06.01.2022
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Year of Publication 06.01.2022
Patent
Unraveling the clinicopathological features driving the emergence of ESR1 mutations in metastatic breast cancer
Kuang, Yanan, Siddiqui, Bilal, Hu, Jiani, Pun, Matthew, Cornwell, MacIntosh, Buchwalter, Gilles, Hughes, Melissa E., Wagle, Nikhil, Kirschmeier, Paul, Jänne, Pasi A., Paweletz, Cloud P., Lin, Nancy U., Krop, Ian E., Barry, William T., Winer, Eric P., Brown, Myles, Jeselsohn, Rinath
Published in NPJ breast cancer (02.08.2018)
Published in NPJ breast cancer (02.08.2018)
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Journal Article
Abstract S1-01: TransCONFIRM: The correlative analysis of breast tumors from patients with advanced hormone receptor positive disease identifies a genetic signature associated with decreased benefit from single agent fulvestrant
Jeselsohn, Rinath M, Barry, William T, Zhao, Jin, Buchwalter, Gilles, Guarducci, Cristina, Migliaccio, Ilenia, Biagioni, Chiara, Bonechi, Martina, Laing, Naomi, Rukazenkov, Yuri, Winer, Eric P, Brown, Myles, Di Leo, Angelo, Malorni, Luca
Published in Cancer research (Chicago, Ill.) (01.05.2015)
Published in Cancer research (Chicago, Ill.) (01.05.2015)
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