Search Results - "BUBENIK Monica" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell-and caspase-based HTS assay. Part 5: Modifications of the 2-and 3-positions

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell-and caspase-based HTS assay. Part 5: Modifications of the 2-and 3-positions

by KEMNITZER, William, SONGCHUN JIANG, GOURDEAU, Henriette, TSENG, Ben, DREWE, John, SUI XIONG CAI, YAN WANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, BUBENIK, Monica, LABRECQUE, Denis, DENIS, Real, LAMOTHE, Serge, ATTARDO, Giorgio
Published in Bioorganic & medicinal chemistry (15.01.2008)

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Journal Article

Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ

Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ

by Bubenik, Monica, Mader, Pavel, Mochirian, Philippe, Vallée, Fréderic, Clark, Jillian, Truchon, Jean-François, Perryman, Alexander L., Pau, Victor, Kurinov, Igor, Zahn, Karl E., Leclaire, Marie-Eve, Papp, Robert, Mathieu, Marie-Claude, Hamel, Martine, Duffy, Nicole M., Godbout, Claude, Casas-Selves, Matias, Falgueyret, Jean-Pierre, Baruah, Prasamit S., Nicolas, Olivier, Stocco, Rino, Poirier, Hugo, Martino, Giovanni, Fortin, Alexanne Bonneau, Roulston, Anne, Chefson, Amandine, Dorich, Stéphane, St-Onge, Miguel, Patel, Purvish, Pellerin, Charles, Ciblat, Stéphane, Pinter, Thomas, Barabé, Francis, El Bakkouri, Majida, Parikh, Paranjay, Gervais, Christian, Sfeir, Agnel, Mamane, Yael, Morris, Stephen J., Black, W. Cameron, Sicheri, Frank, Gallant, Michel
Published in Journal of medicinal chemistry (13.10.2022)

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Journal Article

N-카복스아마이드 화합물 및 인간 중합효소 세타를 저해하기 위한 이의 용도

N-카복스아마이드 화합물 및 인간 중합효소 세타를 저해하기 위한 이의 용도

by PERRYMAN ALEXANDER, MOCHIRIAN PHILIPPE, SURPRENANT SIMON, DIETRICH EVELYNE, BENDAHAN DAVID, GALLANT MICHEL, SOW BOUBACAR, SZYCHOWSKI JANEK, BUBENIK MONICA, LIU BINGCAN
Year of Publication 28.06.2024

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Patent

Synthesis and structural and magnetic properties of mononuclear, dinuclear, and tetranuclear copper(II) complexes of a 17-membered macrocyclic ligand (HM3), capable of forming endogenous phenoxide and pyridazino bridges. X-ray crystal structures of [Cu2(M3)(.mu.2-OMe)(NO3)2], [Cu4(M3)2(.mu.3-OMe)2(.mu.2-Cl)2Cl2], [Cu4(M3)2(.mu.3-OEt)2(.mu.2-N3)2(N3)2](MeOH), [Cu4(M3)2(.mu.3-OMe)2(NCS)4](DMF), and [Cu(M3)(NCS)2]

Synthesis and structural and magnetic properties of mononuclear, dinuclear, and tetranuclear copper(II) complexes of a 17-membered macrocyclic ligand (HM3), capable of forming endogenous phenoxide and pyridazino bridges. X-ray crystal structures of [Cu2(M3)(.mu.2-OMe)(NO3)2], [Cu4(M3)2(.mu.3-OMe)2(.mu.2-Cl)2Cl2], [Cu4(M3)2(.mu.3-OEt)2(.mu.2-N3)2(N3)2](MeOH), [Cu4(M3)2(.mu.3-OMe)2(NCS)4](DMF), and [Cu(M3)(NCS)2]

by Tandon, Santokh. S, Thompson, Laurence K, Bridson, John N, Bubenik, Monica
Published in Inorganic chemistry (01.10.1993)

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Journal Article

Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores

Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores

by Henderson, James A., Bilimoria, Darius, Bubenik, Monica, Cadilhac, Caroline, Cottrell, Kevin M., Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Falardeau, Guy, Giroux, Simon, L’Heureux, Lucille, Liu, Bingcan, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Pereira, Oswy Z., Poisson, Carl, Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Vaillancourt, Louis, Wang, Jian, Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)

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Journal Article

Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency

Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency

by Henderson, James A., Bilimoria, Darius, Bubenik, Monica, Cadilhac, Caroline, Cottrell, Kevin M., Dietrich, Evelyne, Denis, Francois, Ewing, Nigel, Falardeau, Guy, Giroux, Simon, Grey, Ronald, L’Heureux, Lucille, Liu, Bingcan, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Pereira, Oswy Z., Poisson, Carl, Govinda Rao, B., Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Vaillancourt, Louis, Wang, Jian, Yannopoulos, Constantin G., Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)

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Journal Article

Diastereoselective Arbuzov dealkylation of cobalt(III) perfluoroalkyl prochiral phosphonite complexes

Diastereoselective Arbuzov dealkylation of cobalt(III) perfluoroalkyl prochiral phosphonite complexes

by Jablonski, Chet R, Ma, Huaizhu, Chen, Zhao, Hynes, Rosemary C, Bridson, John N, Bubenik, Monica P
Published in Organometallics (01.03.1993)

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Journal Article

A novel RGD antagonist that targets both αvβ3 and α5β1 induces apoptosis of angiogenic endothelial cells on type I collagen

A novel RGD antagonist that targets both αvβ3 and α5β1 induces apoptosis of angiogenic endothelial cells on type I collagen

by Meerovitch, Karen, Bergeron, Frédéric, Leblond, Lorraine, Grouix, Brigitte, Poirier, Cathy, Bubenik, Monica, Chan, Laval, Gourdeau, Henriette, Bowlin, Terry, Attardo, Giorgio
Published in Vascular pharmacology (2003)

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Journal Article

Products of the addition of 1,4-naphthoquinone to an acecyclone

Products of the addition of 1,4-naphthoquinone to an acecyclone

by Bubenik, Monica P., Bridson, John N., Miller, David O., Jean Burnell, D.
Published in Tetrahedron letters (05.03.2007)

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Journal Article

2 IMIDAZOPYRIDAZINES USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY

2 IMIDAZOPYRIDAZINES USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY

by FOURNIER PIERRE ANDRE, FARMER LUC J, LACOSTE JEAN ERIC, LESSARD STEPHANIE, BUBENIK MONICA, STURINO CLAUDIO, LIU BINGCAN, VALLEE FREDERIC, RAMTOHUL YEEMAN, SZYCHOWSKI JANEK, YANNOPOULOS CONSTANTIN, ST ONGE MIGUEL, MARTEL JULIEN, SAYEGH CAMIL ELIE
Year of Publication 27.05.2016

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Patent

Novel nucleotide phosphonate analogues with potent antitumor activity

Novel nucleotide phosphonate analogues with potent antitumor activity

by Bubenik, Monica, Rej, Rabindra, Nguyen-Ba, Nghe, Attardo, Giorgio, Ouellet, France, Chan, Laval
Published in Bioorganic & medicinal chemistry letters (04.11.2002)

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Journal Article

A stereoselective route to bioactive nucleotide phosphonate analogs

A stereoselective route to bioactive nucleotide phosphonate analogs

by Bubenik, Monica, Préville, Patrice, Dugas, Josée, Attardo, Giorgio, Chan, Laval
Published in Tetrahedron letters (03.11.2003)

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Journal Article

Discovery of 4-aryl-4 H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: Modifications of the 2- and 3-positions

Discovery of 4-aryl-4 H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: Modifications of the 2- and 3-positions

by Kemnitzer, William, Jiang, Songchun, Wang, Yan, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Bubenik, Monica, Labrecque, Denis, Denis, Real, Lamothe, Serge, Attardo, Giorgio, Gourdeau, Henriette, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (2008)

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Journal Article

POLO-LIKE KINASE 4 (PLK4) INHIBITORS, PHARMACEUTICAL COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF

POLO-LIKE KINASE 4 (PLK4) INHIBITORS, PHARMACEUTICAL COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF

by SOW, Boubacar, PERRYMAN, Alexander, LIU, Bingcan, VALLÉE, Frédéric, DUPLESSIS, Martin, MOCHIRIAN, Philippe, SURPRENANT, Simon, BUBENIK, Monica, GALLANT, Michel
Year of Publication 03.10.2024

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Patent

Thiophene-based vitronectin receptor antagonists

Thiophene-based vitronectin receptor antagonists

by Bubenik, Monica, Meerovitch, Karen, Bergeron, Frédéric, Attardo, Giorgio, Chan, Laval
Published in Bioorganic & medicinal chemistry letters (10.02.2003)

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Journal Article

N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (THIAZOLYL)])(SUBSTITUTED)CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING HUMAN POLYMERASE THETA

N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (THIAZOLYL)])(SUBSTITUTED)CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING HUMAN POLYMERASE THETA

by PERRYMAN, Alexander, SOW, Boubacar, LIU, Bingcan, MOCHIRIAN, Philippe, SURPRENANT, Simon, BENDAHAN, David, BUBENIK, Monica, SZYCHOWSKI, Janek, DIETRICH, Evelyne, GALLANT, Michel
Year of Publication 07.08.2024

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Patent

POLO-LIKE KINASE 4 (PLK4) INHIBITORS, PHARMACEUTICAL COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF

POLO-LIKE KINASE 4 (PLK4) INHIBITORS, PHARMACEUTICAL COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF

by SOW, Boubacar, LIU, Bingcan, VALLÉE, Frédéric, DUPLESSIS, Martin, MOCHIRIAN, Philippe, SURPRENANT, Simon, BUBENIK, Monica, GALLANT, Michel
Year of Publication 31.08.2023

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Patent

N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (THIAZOLYL)])(SUBSTITUTED)CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING HUMAN POLYMERASE THETA

N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (THIAZOLYL)])(SUBSTITUTED)CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING HUMAN POLYMERASE THETA

by PERRYMAN, Alexander, SOW, Boubacar, LIU, Bingcan, MOCHIRIAN, Philippe, SURPRENANT, Simon, BENDAHAN, David, BUBENIK, Monica, SZYCHOWSKI, Janek, DIETRICH, Evelyne, GALLANT, Michel
Year of Publication 04.04.2024

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Patent

POLO-LIKE KINASE 4 (PLK4) INHIBITORS, PHARMACEUTICAL COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF

POLO-LIKE KINASE 4 (PLK4) INHIBITORS, PHARMACEUTICAL COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF

by SOW, Boubacar, PERRYMAN, Alexander, LIU, Bingcan, VALLÉE, Frédéric, DUPLESSIS, Martin, MOCHIRIAN, Philippe, SURPRENANT, Simon, BUBENIK, Monica, GALLANT, Michel
Year of Publication 21.03.2024

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Patent

1,3,4-THIADIAZOL-2-YL CARBOXAMIDE AND 1,3-THIAZOL-2-YL CARBOXAMIDE COMPOUNDS AND USES THEREOF AS INHIBITORS OF HUMAN POLYMERASE THETA

1,3,4-THIADIAZOL-2-YL CARBOXAMIDE AND 1,3-THIAZOL-2-YL CARBOXAMIDE COMPOUNDS AND USES THEREOF AS INHIBITORS OF HUMAN POLYMERASE THETA

by BLACK, Cameron, PERRYMAN, Alexander, SOW, Boubacar, MORRIS, Stephen, LIU, Bingcan, MOCHIRIAN, Philippe, SURPRENANT, Simon, BENDAHAN, David, BUBENIK, Monica, SZYCHOWSKI, Janek, DIETRICH, Evelyne, GALLANT, Michel
Year of Publication 03.10.2024

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Patent

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