DNA Repair in Prostate Cancer: Biology and Clinical Implications
Mateo, Joaquin, Boysen, Gunther, Barbieri, Christopher E, Bryant, Helen E, Castro, Elena, Nelson, Pete S, Olmos, David, Pritchard, Colin C, Rubin, Mark A, de Bono, Johann S
Published in European urology (01.03.2017)
Published in European urology (01.03.2017)
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Metal Complexes for Two‐Photon Photodynamic Therapy: A Cyclometallated Iridium Complex Induces Two‐Photon Photosensitization of Cancer Cells under Near‐IR Light
McKenzie, Luke K., Sazanovich, Igor V., Baggaley, Elizabeth, Bonneau, Mickaële, Guerchais, Véronique, Williams, J. A. Gareth, Weinstein, Julia A., Bryant, Helen E.
Published in Chemistry : a European journal (05.01.2017)
Published in Chemistry : a European journal (05.01.2017)
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Reduced Expression of miRNA-27a Modulates Cisplatin Resistance in Bladder Cancer by Targeting the Cystine/Glutamate Exchanger SLC7A11
DRAYTON, Ross M, DUDZIEC, Ewa, PETER, Stefan, BERTZ, Simone, HARTMANN, Arndt, BRYANT, Helen E, CATTO, James WF
Published in Clinical cancer research (01.04.2014)
Published in Clinical cancer research (01.04.2014)
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PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts
Piberger, Ann Liza, Bowry, Akhil, Kelly, Richard D. W., Walker, Alexandra K., González-Acosta, Daniel, Bailey, Laura J., Doherty, Aidan J., Méndez, Juan, Morris, Joanna R., Bryant, Helen E., Petermann, Eva
Published in Nature communications (17.11.2020)
Published in Nature communications (17.11.2020)
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PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination
Bryant, Helen E, Petermann, Eva, Schultz, Niklas, Jemth, Ann-Sofie, Loseva, Olga, Issaeva, Natalia, Johansson, Fredrik, Fernandez, Serena, McGlynn, Peter, Helleday, Thomas
Published in The EMBO journal (02.09.2009)
Published in The EMBO journal (02.09.2009)
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Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP) – Function in Genome Maintenance and Relevance of Inhibitors for Anti-cancer Therapy
Harrision, Daniel, Gravells, Polly, Thompson, Ruth, Bryant, Helen E.
Published in Frontiers in molecular biosciences (28.08.2020)
Published in Frontiers in molecular biosciences (28.08.2020)
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Synthesis and Aggregation of a Porphyrin-Cored Hyperbranched Polyglycidol and Its Application as a Macromolecular Photosensitizer for Photodynamic Therapy
Kadhim, Alaa, McKenzie, Luke K, Bryant, Helen E, Twyman, Lance James
Published in Molecular pharmaceutics (04.03.2019)
Published in Molecular pharmaceutics (04.03.2019)
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DNA damage repair in breast cancer and its therapeutic implications
Ali, Reem, Rakha, Emad A., Madhusudan, Srinivasan, Bryant, Helen E.
Published in Pathology (01.02.2017)
Published in Pathology (01.02.2017)
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Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination―Defective Cells
GOTTIPATI, Ponnari, VISCHIONI, Barbara, SCHULTZ, Niklas, SOLOMONS, Joyce, BRYANT, Helen E, DJUREINOVIC, Tatjana, ISSAEVA, Natalia, SLEETH, Kate, SHARMA, Ricky A, HELLEDAY, Thomas
Published in Cancer research (Chicago, Ill.) (01.07.2010)
Published in Cancer research (Chicago, Ill.) (01.07.2010)
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A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations
Saldana-Guerrero, Ingrid M., Montano-Gutierrez, Luis F., Boswell, Katy, Hafemeister, Christoph, Poon, Evon, Shaw, Lisa E., Stavish, Dylan, Lea, Rebecca A., Wernig-Zorc, Sara, Bozsaky, Eva, Fetahu, Irfete S., Zoescher, Peter, Pötschger, Ulrike, Bernkopf, Marie, Wenninger-Weinzierl, Andrea, Sturtzel, Caterina, Souilhol, Celine, Tarelli, Sophia, Shoeb, Mohamed R., Bozatzi, Polyxeni, Rados, Magdalena, Guarini, Maria, Buri, Michelle C., Weninger, Wolfgang, Putz, Eva M., Huang, Miller, Ladenstein, Ruth, Andrews, Peter W., Barbaric, Ivana, Cresswell, George D., Bryant, Helen E., Distel, Martin, Chesler, Louis, Taschner-Mandl, Sabine, Farlik, Matthias, Tsakiridis, Anestis, Halbritter, Florian
Published in Nature communications (03.05.2024)
Published in Nature communications (03.05.2024)
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ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage
Willan, Jessica, Cleasby, Alexa J., Flores-Rodriguez, Neftali, Stefani, Flavia, Rinaldo, Cinzia, Pisciottani, Alessandra, Grant, Emma, Woodman, Philip, Bryant, Helen E., Ciani, Barbara
Published in Oncogenesis (New York, NY) (15.04.2019)
Published in Oncogenesis (New York, NY) (15.04.2019)
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Spontaneous Homologous Recombination Is Induced by Collapsed Replication Forks That Are Caused by Endogenous DNA Single-Strand Breaks
Saleh-Gohari, Nasrollah, Bryant, Helen E, Schultz, Niklas, Parker, Kayan M, Cassel, Tobias N, Helleday, Thomas
Published in Molecular and Cellular Biology (01.08.2005)
Published in Molecular and Cellular Biology (01.08.2005)
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Targeting OGG1 and PARG radiosensitises head and neck cancer cells to high-LET protons through complex DNA damage persistence
Fabbrizi, Maria Rita, Nickson, Catherine M., Hughes, Jonathan R., Robinson, Emily A., Vaidya, Karthik, Rubbi, Carlos P., Kacperek, Andrzej, Bryant, Helen E., Helleday, Thomas, Parsons, Jason L.
Published in Cell death & disease (17.02.2024)
Published in Cell death & disease (17.02.2024)
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Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma
George, Sally L, Lorenzi, Federica, King, David, Hartlieb, Sabine, Campbell, James, Pemberton, Helen, Toprak, Umut H, Barker, Karen, Tall, Jennifer, da Costa, Barbara Martins, van den Boogaard, Marlinde L, Dolman, M Emmy M, Molenaar, Jan J, Bryant, Helen E, Westermann, Frank, Lord, Christopher J, Chesler, Louis
Published in EBioMedicine (01.09.2020)
Published in EBioMedicine (01.09.2020)
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Poly(ADP-ribose) Polymerase (PARP-1) in Homologous Recombination and as a Target for Cancer Therapy
Helleday, Thomas, Bryant, Helen E., Schultz, Niklas
Published in Cell cycle (Georgetown, Tex.) (01.09.2005)
Published in Cell cycle (Georgetown, Tex.) (01.09.2005)
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