A molecular switch regulating transcriptional repression and activation of PPARγ
Shang, Jinsai, Mosure, Sarah A., Zheng, Jie, Brust, Richard, Bass, Jared, Nichols, Ashley, Solt, Laura A., Griffin, Patrick R., Kojetin, Douglas J.
Published in Nature communications (19.02.2020)
Published in Nature communications (19.02.2020)
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Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ
Shang, Jinsai, Brust, Richard, Mosure, Sarah A, Bass, Jared, Munoz-Tello, Paola, Lin, Hua, Hughes, Travis S, Tang, Miru, Ge, Qingfeng, Kamenekca, Theodore M, Kojetin, Douglas J
Published in eLife (21.12.2018)
Published in eLife (21.12.2018)
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A structural mechanism for directing corepressor-selective inverse agonism of PPARγ
Brust, Richard, Shang, Jinsai, Fuhrmann, Jakob, Mosure, Sarah A., Bass, Jared, Cano, Andrew, Heidari, Zahra, Chrisman, Ian M., Nemetchek, Michelle D., Blayo, Anne-Laure, Griffin, Patrick R., Kamenecka, Theodore M., Hughes, Travis S., Kojetin, Douglas J.
Published in Nature communications (08.11.2018)
Published in Nature communications (08.11.2018)
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Journal Article
Photoactivation of the BLUF Protein PixD Probed by the Site-Specific Incorporation of Fluorotyrosine Residues
Gil, Agnieszka A, Laptenok, Sergey P, Iuliano, James N, Lukacs, Andras, Verma, Anil, Hall, Christopher R, Yoon, Grace E, Brust, Richard, Greetham, Gregory M, Towrie, Michael, French, Jarrod B, Meech, Stephen R, Tonge, Peter J
Published in Journal of the American Chemical Society (18.10.2017)
Published in Journal of the American Chemical Society (18.10.2017)
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Journal Article
Proteins in Action: Femtosecond to Millisecond Structural Dynamics of a Photoactive Flavoprotein
Brust, Richard, Lukacs, Andras, Haigney, Allison, Addison, Kiri, Gil, Agnieszka, Towrie, Michael, Clark, Ian P, Greetham, Gregory M, Tonge, Peter J, Meech, Stephen R
Published in Journal of the American Chemical Society (30.10.2013)
Published in Journal of the American Chemical Society (30.10.2013)
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Journal Article
Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1
de Vera, Ian Mitchelle S, Giri, Pankaj K, Munoz-Tello, Paola, Brust, Richard, Fuhrmann, Jakob, Matta-Camacho, Edna, Shang, Jinsai, Campbell, Sean, Wilson, Henry D, Granados, Juan, Gardner, William J, Creamer, Trevor P, Solt, Laura. A, Kojetin, Douglas J
Published in ACS chemical biology (15.07.2016)
Published in ACS chemical biology (15.07.2016)
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Journal Article
Complete Proton Transfer Cycle in GFP and Its T203V and S205V Mutants
Laptenok, Sergey P., Lukacs, Andras, Gil, Agnieszka, Brust, Richard, Sazanovich, Igor V., Greetham, Gregory M., Tonge, Peter J., Meech, Stephen R.
Published in Angewandte Chemie International Edition (03.08.2015)
Published in Angewandte Chemie International Edition (03.08.2015)
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Journal Article
Photoexcitation of the Blue Light Using FAD Photoreceptor AppA Results in Ultrafast Changes to the Protein Matrix
Lukacs, Andras, Haigney, Allison, Brust, Richard, Zhao, Rui-Kun, Stelling, Allison L, Clark, Ian P, Towrie, Michael, Greetham, Gregory M, Meech, Stephen R, Tonge, Peter J
Published in Journal of the American Chemical Society (26.10.2011)
Published in Journal of the American Chemical Society (26.10.2011)
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Journal Article
Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: Effect of the Y21 pKa on the Forward and Reverse Ground-State Reactions
Gil, Agnieszka, Haigney, Allison, Laptenok, Sergey P, Brust, Richard, Lukacs, Andras, Iuliano, James, Jeng, Jessica, Melief, Eduard, Zhao, Rui-Kun, Yoon, EunBin, Clark, Ian, Towrie, Michael, Greetham, Gregory M, Ng, Annabelle, Truglio, James, French, Jarrod, Meech, Stephen R, Tonge, Peter J
Published in Journal of the American Chemical Society (27.01.2016)
Published in Journal of the American Chemical Society (27.01.2016)
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Journal Article
Protein Photochromism Observed by Ultrafast Vibrational Spectroscopy
Lukacs, Andras, Haigney, Allison, Brust, Richard, Addison, Kiri, Towrie, Michael, Greetham, Gregory M, Jones, Garth A, Miyawaki, Atsushi, Tonge, Peter J, Meech, Stephen R
Published in The journal of physical chemistry. B (10.10.2013)
Published in The journal of physical chemistry. B (10.10.2013)
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Journal Article
Excited State Structure and Dynamics of the Neutral and Anionic Flavin Radical Revealed by Ultrafast Transient Mid-IR to Visible Spectroscopy
Lukacs, Andras, Zhao, Rui-Kun, Haigney, Allison, Brust, Richard, Greetham, Gregory M, Towrie, Michael, Tonge, Peter J, Meech, Stephen R
Published in The journal of physical chemistry. B (24.05.2012)
Published in The journal of physical chemistry. B (24.05.2012)
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Journal Article
Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii
Brust, Richard, Haigney, Allison, Lukacs, Andras, Gil, Agnieszka, Hossain, Shahrier, Addison, Kiri, Lai, Cheng-Tsung, Towrie, Michael, Greetham, Gregory M, Clark, Ian P, Illarionov, Boris, Bacher, Adelbert, Kim, Ryu-Ryun, Fischer, Markus, Simmerling, Carlos, Meech, Stephen R, Tonge, Peter J
Published in The journal of physical chemistry letters (02.01.2014)
Published in The journal of physical chemistry letters (02.01.2014)
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Journal Article
Electron transfer quenching in light adapted and mutant forms of the AppA BLUF domain
Laptenok, Sergey P, Lukacs, Andras, Brust, Richard, Haigney, Allison, Gil, Agnieszka, Towrie, Michael, Greetham, Gregory M, Tonge, Peter J, Meech, Stephen R
Published in Faraday discussions (01.01.2015)
Published in Faraday discussions (01.01.2015)
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Journal Article
Vibrational Assignment of the Ultrafast Infrared Spectrum of the Photoactivatable Flavoprotein AppA
Haigney, Allison, Lukacs, Andras, Brust, Richard, Zhao, Rui-Kun, Towrie, Michael, Greetham, Gregory M, Clark, Ian, Illarionov, Boris, Bacher, Adelbert, Kim, Ryu-Ryun, Fischer, Markus, Meech, Stephen R, Tonge, Peter J
Published in The journal of physical chemistry. B (06.09.2012)
Published in The journal of physical chemistry. B (06.09.2012)
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Journal Article
Ultrafast Infrared Spectroscopy of an Isotope-Labeled Photoactivatable Flavoprotein
Haigney, Allison, Lukacs, Andras, Zhao, Rui-Kun, Stelling, Allison L, Brust, Richard, Kim, Ryu-Ryun, Kondo, Minako, Clark, Ian, Towrie, Michael, Greetham, Gregory M, Illarionov, Boris, Bacher, Adelbert, Römisch-Margl, Werner, Fischer, Markus, Meech, Stephen R, Tonge, Peter J
Published in Biochemistry (Easton) (01.03.2011)
Published in Biochemistry (Easton) (01.03.2011)
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A Comparison of Hybridization between Mottled Ducks (Anas fulvigula)and Mallards (A. platyrhynchos) in Florida and South Carolina using Microsatellite DNA Analysis
Williams, Christen L, Brust, Richard C, Fendley, Timothy T, Tiller, Gerald R, Rhodes, Olin E
Published in Conservation genetics (01.05.2005)
Published in Conservation genetics (01.05.2005)
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Journal Article
Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone
Mosure, Sarah A, Shang, Jinsai, Eberhardt, Jerome, Brust, Richard, Zheng, Jie, Griffin, Patrick R, Forli, Stefano, Kojetin, Douglas J
Published in Journal of medicinal chemistry (28.02.2019)
Published in Journal of medicinal chemistry (28.02.2019)
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Journal Article
Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA
de Vera, Ian Mitchelle S., Zheng, Jie, Novick, Scott, Shang, Jinsai, Hughes, Travis S., Brust, Richard, Munoz-Tello, Paola, Gardner, William J., Marciano, David P., Kong, Xiangming, Griffin, Patrick R., Kojetin, Douglas J.
Published in Structure (London) (03.10.2017)
Published in Structure (London) (03.10.2017)
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