Arteriolar niches maintain haematopoietic stem cell quiescence
Kunisaki, Yuya, Bruns, Ingmar, Scheiermann, Christoph, Ahmed, Jalal, Pinho, Sandra, Zhang, Dachuan, Mizoguchi, Toshihide, Wei, Qiaozhi, Lucas, Daniel, Ito, Keisuke, Mar, Jessica C, Bergman, Aviv, Frenette, Paul S
Published in Nature (London) (31.10.2013)
Published in Nature (London) (31.10.2013)
Get full text
Journal Article
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration
Lucas, Daniel, Scheiermann, Christoph, Chow, Andrew, Kunisaki, Yuya, Bruns, Ingmar, Barrick, Colleen, Tessarollo, Lino, Frenette, Paul S
Published in Nature medicine (01.06.2013)
Published in Nature medicine (01.06.2013)
Get full text
Journal Article
Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells
Rosenbauer, Frank, Bruns, Ingmar, Steidl, Christian, Wagner, Katharina, Aivado, Manuel, Delwel, Ruud, Passegué, Emmanuelle, Klippel, Steffen, Otu, Hasan H, Valk, Peter J M, Verhaak, Roel G W, Ebralidze, Alexander, Costa, Daniel B, Steidl, Ulrich, Tenen, Daniel G, Gu, Xuesong, Libermann, Towia A, Kobbe, Guido
Published in Nature genetics (01.11.2006)
Published in Nature genetics (01.11.2006)
Get full text
Journal Article
The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway
Singh, Raminder, Cadeddu, Ron-Patrick, Fröbel, Julia, Wilk, Christian Matthias, Bruns, Ingmar, Zerbini, Luiz Fernando, Prenzel, Tanja, Hartwig, Sonja, Brünnert, Daniela, Schroeder, Thomas, Lehr, Stefan, Haas, Rainer, Czibere, Akos
Published in Apoptosis (London) (01.09.2011)
Published in Apoptosis (London) (01.09.2011)
Get full text
Journal Article
Therapy-related myeloid neoplasms following treatment with radioiodine
SCHROEDER, Thomas, KUENDGEN, Andrea, SCHLENK, Richard, CZIBERE, Akos G, BRUNS, Ingmar, FENK, Roland, GATTERMANN, Norbert, HAAS, Rainer, KOBBE, Guido, GERMING, Ulrich, KAYSER, Sabine, KRÖGER, Nicolaus, BRAULKE, Friederike, PLATZBECKER, Uwe, KLÄRNER, Viola, ZOHREN, Fabian, HAASE, Detlef, STADLER, Michael
Published in Haematologica (Roma) (01.02.2012)
Published in Haematologica (Roma) (01.02.2012)
Get full text
Journal Article
Low RPS14 expression is common in myelodysplastic syndromes without 5q- aberration and defines a subgroup of patients with prolonged survival
Czibere, Akos, Bruns, Ingmar, Junge, Barbel, Singh, Raminder, Kobbe, Guido, Haas, Rainer, Germing, Ulrich
Published in Haematologica (Roma) (01.10.2009)
Published in Haematologica (Roma) (01.10.2009)
Get full text
Journal Article
Pegylated granulocyte colony-stimulating factor mobilizes CD34+ cells with different stem and progenitor subsets and distinct functional properties in comparison with unconjugated granulocyte colony-stimulating factor
Bruns, Ingmar, Steidl, Ulrich, Fischer, Johannes C, Czibere, Akos, Kobbe, Guido, Raschke, Sascha, Singh, Raminder, Fenk, Roland, Rosskopf, Michael, Pechtel, Sabrina, von Haeseler, Arndt, Wernet, Peter, Tenen, Daniel G, Haas, Rainer, Kronenwett, Ralf
Published in Haematologica (Roma) (01.03.2008)
Published in Haematologica (Roma) (01.03.2008)
Get full text
Journal Article
PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion
Pinho, Sandra, Lacombe, Julie, Hanoun, Maher, Mizoguchi, Toshihide, Bruns, Ingmar, Kunisaki, Yuya, Frenette, Paul S
Published in The Journal of experimental medicine (01.07.2013)
Published in The Journal of experimental medicine (01.07.2013)
Get full text
Journal Article
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion
Bruns, Ingmar, Lucas, Daniel, Pinho, Sandra, Ahmed, Jalal, Lambert, Michele P, Kunisaki, Yuya, Scheiermann, Christoph, Schiff, Lauren, Poncz, Mortimer, Bergman, Aviv, Frenette, Paul S
Published in Nature medicine (01.11.2014)
Published in Nature medicine (01.11.2014)
Get full text
Journal Article
Prognostic Relevance of Fragile Histidine Triad Protein Expression in Patients with Small Cell Lung Cancer
ROHR, Ulrich-Peter, REHFELD, Nina, OPALKA, Bertram, GABBERT, Helmut E, KRONENWETT, Ralf, HAAS, Rainer, GEDDERT, Helene, PFLUGFELDER, Lucy, BRUNS, Ingmar, NEUKIRCH, Judith, ROHRBECK, Astrid, GROTE, Hans J, STEIDL, Ulrich, FENK, Roland
Published in Clinical cancer research (01.01.2005)
Published in Clinical cancer research (01.01.2005)
Get full text
Journal Article
A phase I/II study of maplirpacept in combination with pegylated liposomal doxorubicin (PLD) in patients with platinum-resistant ovarian cancer (OC): Phase 1 results
Street, Daron G., Kuttschreuter, Luke, Starks, David, Mahdi, Haider, Linn, Carlos, Pavlov, Dmitri, Peguero, Julio Antonio, Chawla, Sant P., Bruns, Ingmar, Waggoner, Steven E.
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
Get full text
Journal Article
Safety and clinical activity of TTI-621 in combination with doxorubicin in patients with unresectable or metastatic high-grade leiomyosarcoma: Results from the low-dose expansion cohort
Movva, Sujana, Druta, Mihaela, Davis, Lara E., Monga, Varun, Milhem, Mohammed M., Bailey, Howard Harry, Chugh, Rashmi, Bruns, Ingmar, Allgood, Victoria E, Chawla, Sant P.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
Get full text
Journal Article
A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation
Atrafi, Florence, Boix, Oliver, Subbiah, Vivek, Diamond, Jennifer R, Chawla, Sant P, Tolcher, Anthony W, LoRusso, Patricia M, Eder, Joseph P, Gutierrez, Martin, Sankhala, Kumar, Rajagopalan, Prabhu, Genvresse, Isabelle, Langer, Simon, Mathijssen, Ron H J, Verweij, Jaap, Bruns, Ingmar, Lolkema, Martijn P
Published in Clinical cancer research (01.12.2021)
Published in Clinical cancer research (01.12.2021)
Get full text
Journal Article
TTI-622-01: A phase 1a/1b dose-escalation and expansion trial of TTI-622 in patients with advanced hematologic malignancies, including diffuse large B-cell lymphoma (DLBCL)
Patel, Krish, Sano, Dahlia, Maris, Michael, Lesokhin, Alexander M., Von Keudell, Gottfried, Doucette, Kimberley, Ramchandren, Radhakrishnan, Pavlov, Dmitri, Uger, Robert A., Molloy, Naomi, Bruns, Ingmar, Scheuber, Anita, Iyer, Swaminathan Padmanabhan
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
Get full text
Journal Article
TTI-622-01: A phase 1a/1b dose-escalation and expansion trial of TTI-622 in patients with advanced hematologic malignancies, including multiple myeloma
Patel, Krish, Orlowski, Robert Z., Doucette, Kimberley, Maris, Michael, Pianko, Matthew James, Ramchandren, Radhakrishnan, Stevens, Don A., Vesole, David H., Uger, Robert A., Scheuber, Anita, Molloy, Naomi, Bruns, Ingmar, Lesokhin, Alexander M.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
Get full text
Journal Article
TTI-621-03: A phase I/II study of TTI-621 in combination with doxorubicin in patients with unresectable or metastatic high-grade leiomyosarcoma (LMS)
Chawla, Sant P., Kelly, Ciara Marie, Gordon, Erlinda Maria, Quon, Doris V., Moradkhani, Ania, Chua-Alcala, Victoria S., Thompson, Theresa M., Scheuber, Anita, Bruns, Ingmar, Allgood, Victoria E., Movva, Sujana
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
Get full text
Journal Article
CD47-Blocker TTI-622 Shows Single-Agent Activity in Patients with Advanced Relapsed or Refractory Lymphoma: Update from the Ongoing First-in-Human Dose Escalation Study
Patel, Krish, Zonder, Jeffrey A., Sano, Dahlia, Maris, Michael, Lesokhin, Alexander, von Keudell, Gottfried, Lai, Catherine, Ramchandren, Rod, Catalano, Tina, Lin, Gloria H.Y., Uger, Bob, Petrova, Penka S., Molloy, Naomi, Bruns, Ingmar, Iyer, Swaminathan P
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
Get full text
Journal Article
Correction: A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation
Atrafi, Florence, Boix, Oliver, Subbiah, Vivek, Diamond, Jennifer R., Chawla, Sant P., Tolcher, Anthony W., LoRusso, Patricia M., Eder, Joseph P., Gutierrez, Martin, Sankhala, Kumar, Rajagopalan, Prabhu, Genvresse, Isabelle, Langer, Simon, Mathijssen, Ron H.J., Verweij, Jaap, Bruns, Ingmar, Lolkema, Martijn P.
Published in Clinical cancer research (01.07.2022)
Published in Clinical cancer research (01.07.2022)
Get full text
Journal Article