Pyrazolyl-Ureas as Interesting Scaffold in Medicinal Chemistry
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Published in Molecules (Basel, Switzerland) (29.07.2020)
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New Hybrid Pyrazole and Imidazopyrazole Antinflammatory Agents Able to Reduce ROS Production in Different Biological Targets
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Published in Molecules (Basel, Switzerland) (18.02.2020)
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Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease
Ricciarelli, Roberta, Brullo, Chiara, Prickaerts, Jos, Arancio, Ottavio, Villa, Carla, Rebosio, Claudia, Calcagno, Elisa, Balbi, Matilde, van Hagen, Britt T J, Argyrousi, Elentina K, Zhang, Hong, Pronzato, Maria Adelaide, Bruno, Olga, Fedele, Ernesto
Published in Scientific reports (12.04.2017)
Published in Scientific reports (12.04.2017)
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The Pyrazolyl-Urea Gege3 Inhibits the Activity of ANXA1 in the Angiogenesis Induced by the Pancreatic Cancer Derived EVs
Belvedere, Raffaella, Morretta, Elva, Novizio, Nunzia, Morello, Silvana, Bruno, Olga, Brullo, Chiara, Petrella, Antonello
Published in Biomolecules (Basel, Switzerland) (24.11.2021)
Published in Biomolecules (Basel, Switzerland) (24.11.2021)
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Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition
Cavalloro, Valeria, Russo, Katia, Vasile, Francesca, Pignataro, Luca, Torretta, Archimede, Donini, Stefano, Semrau, Marta S, Storici, Paola, Rossi, Daniela, Rapetti, Federica, Brullo, Chiara, Parisini, Emilio, Bruno, Olga, Collina, Simona
Published in Molecules (Basel, Switzerland) (19.02.2020)
Published in Molecules (Basel, Switzerland) (19.02.2020)
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Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles
Cichero, Elena, Tonelli, Michele, Novelli, Federica, Tasso, Bruno, Delogu, Ilenia, Loddo, Roberta, Bruno, Olga, Fossa, Paola
Published in Journal of enzyme inhibition and medicinal chemistry (2017)
Published in Journal of enzyme inhibition and medicinal chemistry (2017)
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New Selective Phosphodiesterase 4D Inhibitors Differently Acting on Long, Short, and Supershort Isoforms
Bruno, Olga, Romussi, Alessia, Spallarossa, Andrea, Brullo, Chiara, Schenone, Silvia, Bondavalli, Francesco, Vanthuyne, Nicolas, Roussel, Christian
Published in Journal of medicinal chemistry (12.11.2009)
Published in Journal of medicinal chemistry (12.11.2009)
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Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines
Schenone, Silvia, Brullo, Chiara, Bruno, Olga, Bondavalli, Francesco, Mosti, Luisa, Maga, Giovanni, Crespan, Ernmanuele, Carraro, Fabio, Manetti, Fabrizio, Tintori, Cristina, Botta, Maurizio
Published in European journal of medicinal chemistry (01.12.2008)
Published in European journal of medicinal chemistry (01.12.2008)
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Pyrazole and imidazo[1,2-b]pyrazole Derivatives as New Potential Antituberculosis Agents
Meta, Elda, Brullo, Chiara, Tonelli, Michele, Franzblau, Scott G, Wang, Yuehong, Ma, Rui, Baojie, Wan, Orena, Beatrice S, Pasca, Maria R, Bruno, Olga
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (2019)
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (2019)
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Identification of a Novel Pyrazolo[3,4-d]pyrimidine Able To Inhibit Cell Proliferation of a Human Osteogenic Sarcoma in Vitro and in a Xenograft Model in Mice
Manetti, Fabrizio, Santucci, Annalisa, Locatelli, Giada A, Maga, Giovanni, Spreafico, Adriano, Serchi, Tommaso, Orlandini, Maurizio, Bernardini, Giulia, Caradonna, Nicola P, Spallarossa, Andrea, Brullo, Chiara, Schenone, Silvia, Bruno, Olga, Ranise, Angelo, Bondavalli, Francesco, Hoffmann, Oskar, Bologna, Mauro, Angelucci, Adriano, Botta, Maurizio
Published in Journal of medicinal chemistry (15.11.2007)
Published in Journal of medicinal chemistry (15.11.2007)
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Synthesis, antiplatelet and antithrombotic activities of new 2-substituted benzopyrano[4,3-d]pyrimidin-4-cycloamines and 4-amino/cycloamino-benzopyrano[4,3-d]pyrimidin-5-ones
BRUNO, Olga, BRULLO, Chiara, SCHENONE, Silvia, BONDAVALLI, Francesco, RANISE, Angelo, TOGNOLINI, Massimiliano, IMPICCIATORE, Mariannina, BALLABENI, Vigilio, BAROCELLI, Elisabetta
Published in Bioorganic & medicinal chemistry (2006)
Published in Bioorganic & medicinal chemistry (2006)
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Pyrazolo[3,4-d]pyrimidines as Potent Antiproliferative and Proapoptotic Agents toward A431 and 8701-BC Cells in Culture via Inhibition of c-Src Phosphorylation
Carraro, Fabio, Naldini, Antonella, Pucci, Annalisa, Locatelli, Giada A, Maga, Giovanni, Schenone, Silvia, Bruno, Olga, Ranise, Angelo, Bondavalli, Francesco, Brullo, Chiara, Fossa, Paola, Menozzi, Giulia, Mosti, Luisa, Modugno, Michele, Tintori, Cristina, Manetti, Fabrizio, Botta, Maurizio
Published in Journal of medicinal chemistry (09.03.2006)
Published in Journal of medicinal chemistry (09.03.2006)
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Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line
Schenone, S, Bruno, O, Bondavalli, F, Ranise, A, Mosti, L, Menozzi, G, Fossa, P, Donnini, S, Santoro, A, Ziche, M, Manetti, F, Botta, M
Published in European journal of medicinal chemistry (01.11.2004)
Published in European journal of medicinal chemistry (01.11.2004)
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Synthesis and Biological Evaluation of N-Pyrazolyl-N‘-alkyl/benzyl/phenylureas: a New Class of Potent Inhibitors of Interleukin 8-Induced Neutrophil Chemotaxis
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Published in Journal of medicinal chemistry (26.07.2007)
Published in Journal of medicinal chemistry (26.07.2007)
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Parallel one-pot synthesis and structure–activity relationship study of symmetric formimidoester disulfides as a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors
Cesarini, Sara, Spallarossa, Andrea, Ranise, Angelo, Schenone, Silvia, Bruno, Olga, La Colla, Paolo, Casula, Laura, Collu, Gabriella, Sanna, Giuseppina, Loddo, Roberta
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Relative stereochemistry of a diterpene from Salvia cinnabarina
Bisio, Angela, Pagano, Bruno, Romussi, Alessia, Bruno, Olga, De Tommasi, Nunziatina, Romussi, Giovanni, Mattia, Carlo Andrea
Published in Molecules (Basel, Switzerland) (10.10.2007)
Published in Molecules (Basel, Switzerland) (10.10.2007)
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3-Arylsulphonyl-5-arylamino-1,3,4-thiadiazol-2(3 H)ones as anti-inflammatory and analgesic agents
Schenone, Silvia, Bruno, Olga, Ranise, Angelo, Bondavalli, Francesco, Filippelli, Walter, Falcone, Giuseppe, Giordano, Lucio, Vitelli, Maria Redenta
Published in Bioorganic & medicinal chemistry (01.08.2001)
Published in Bioorganic & medicinal chemistry (01.08.2001)
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Substituted Pyrazolo[3,4-b]pyridines as Potent A1 Adenosine Antagonists: Synthesis, Biological Evaluation, and Development of an A1 Bovine Receptor Model
Tuccinardi, Tiziano, Schenone, Silvia, Bondavalli, Francesco, Brullo, Chiara, Bruno, Olga, Mosti, Luisa, Zizzari, Alessandra Tania, Tintori, Cristina, Manetti, Fabrizio, Ciampi, Osele, Trincavelli, Maria Letizia, Martini, Claudia, Martinelli, Adriano, Botta, Maurizio
Published in ChemMedChem (16.06.2008)
Published in ChemMedChem (16.06.2008)
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Synthesis, functional proteomics and biological evaluation of new 5-pyrazolyl ureas as potential anti-angiogenic compounds
Morretta, Elva, Sidibè, Adama, Spallarossa, Andrea, Petrella, Antonello, Meta, Elda, Bruno, Olga, Monti, Maria Chiara, Brullo, Chiara
Published in European journal of medicinal chemistry (15.12.2021)
Published in European journal of medicinal chemistry (15.12.2021)
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